HTML Microdata document

This HTML5 document contains 3431 embedded RDF statements represented using HTML+Microdata notation.

The embedded RDF content will be recognized by any processor of HTML5 Microdata.

Namespace Prefixes

Prefix	IRI
xsdh	http://www.w3.org/2001/XMLSchema#
n7	http://pubannotation.org/docs/sourcedb/PMC/sourceid/
n10	http://dx.doi.org/
n8	http://purl.org/spar/doco/
n3	http://purl.jp/bio/10/colil/id/
dc	http://purl.org/dc/elements/1.1/
n11	http://togows.dbcls.jp/entry/pubmed/
n9	http://www.ncbi.nlm.nih.gov/pmc/articles/
n2	http://purl.jp/bio/10/colil/ontology/201303#
rdfs	http://www.w3.org/2000/01/rdf-schema#
bibo	http://purl.org/ontology/bibo/
rdf	http://www.w3.org/1999/02/22-rdf-syntax-ns#

Statements

Subject Item: n3:15240568
rdf:type: n2:CitationPaper n2:RelevantPaper n2:ReferencePaper
rdfs:seeAlso: n7:0 n9:0 n10:10.1083%2Fjcb.200311021 n11:15240568
bibo:cites: n3:11514554 n3:9119111 n3:10545105 n3:10753864 n3:11729123 n3:7990924 n3:2905686 n3:9774680 n3:9171829 n3:9827568 n3:8001137 n3:12408869 n3:12408868 n3:7677172 n3:9396760 n3:11294915 n3:9065401 n3:9065402 n3:12842915 n3:11733373 n3:12559945 n3:10490837 n3:11872843 n3:8787755 n3:4440633 n3:7704017 n3:10934025 n3:9308964 n3:9614107 n3:9727977 n3:12691661 n3:8640233 n3:8090754 n3:9697701 n3:7935448 n3:14698613 n3:11101852 n3:11517178 n3:11335109 n3:12713737 n3:9121483 n3:14517545 n3:11934263 n3:11040183 n3:11807034 n3:9858536 n3:9921649 n3:2100251 n3:10320524 n3:11381089 n3:10777565 n3:12970140 n3:9914172 n3:12514105 n3:11371614 n3:12414734 n3:12095419 n3:10729834 n3:12655639 n3:11799060 n3:14522876 n3:10201372 n3:12865297 n3:12455632 n3:14625550 n3:10862751 n3:9724758 n3:9311916 n3:9036867 n3:9926923 n3:10319868 n3:12878728 n3:12947088
n2:cocitationWith: n3:12093753 n3:18371393 n3:18794899 n3:18794900 n3:29499500 n3:11553815 n3:12037668 n3:15131783 n3:10597251 n3:28187288 n3:19272386 n3:23352663 n3:25220842 n3:18794802 n3:21892181 n3:18794798 n3:10545105 n3:23870119 n3:9990071 n3:15034581 n3:20301211 n3:19736321 n3:23446353 n3:12145803 n3:21600206 n3:21861142 n3:19549527 n3:22766303 n3:22239017 n3:15590741 n3:15198980 n3:10921899 n3:19228882 n3:11819864 n3:15361487 n3:16085486 n3:25603931 n3:22682243 n3:19808100 n3:11756228 n3:24821987 n3:26040697 n3:2188735 n3:24220295 n3:15520178 n3:23306204 n3:24058167 n3:7990924 n3:19619488 n3:19619491 n3:11306549 n3:29706964 n3:20085740 n3:11306497 n3:22761195 n3:9774680 n3:25732745 n3:27471255 n3:21205878 n3:9233789 n3:20103652 n3:25527186 n3:23877564 n3:24308963 n3:12154040 n3:22044670 n3:7666392 n3:19124014 n3:9843981 n3:11792709 n3:20871603 n3:22617420 n3:22617424 n3:27105493 n3:20937839 n3:17234760 n3:17545618 n3:27339979 n3:19589945 n3:17474097 n3:23736260 n3:12612914 n3:22388892 n3:19543319 n3:21321311 n3:21090969 n3:30811997 n3:30927915 n3:16809766 n3:26030748 n3:19924227 n3:17532558 n3:20599897 n3:18593557 n3:10608876 n3:22586121 n3:8001137 n3:20098461 n3:22488688 n3:25278615 n3:12408869 n3:12408868 n3:24480852 n3:8655584 n3:11809809 n3:11809808 n3:29204504 n3:23426182 n3:21532856 n3:13663040 n3:11691783 n3:18628392 n3:16464855 n3:15221008 n3:19933147 n3:18062147 n3:9396760 n3:11507052 n3:26109046 n3:17698607 n3:20565988 n3:15961883 n3:31382142 n3:17030556 n3:19234110 n3:19243219 n3:20122401 n3:10392709 n3:20018966 n3:16481354 n3:18268006 n3:23449223 n3:11564888 n3:17007831 n3:18519685 n3:22246670 n3:16107730 n3:19092804 n3:23660500 n3:1651563 n3:1651562 n3:9065401 n3:9065402 n3:24906622 n3:26276632 n3:16107537 n3:12842915 n3:29110754 n3:15342386 n3:18557758 n3:9749964 n3:17030180 n3:19655378 n3:23774734 n3:16504081 n3:17702866 n3:7937951 n3:20670162 n3:17081971 n3:11689955 n3:17785439 n3:567022 n3:20051105 n3:10192393 n3:22527717 n3:28358093 n3:9212098 n3:29509914 n3:26036262 n3:21113154 n3:17724330 n3:23040474 n3:22177117 n3:28059064 n3:21113151 n3:10898789 n3:11051546 n3:28345602 n3:15473860 n3:21983963 n3:21978911 n3:15473857 n3:11872843 n3:19029987 n3:10802651 n3:17117926 n3:15001769 n3:16510874 n3:11389839 n3:30239619 n3:14668450 n3:27043282 n3:17934449 n3:24550486 n3:19379690 n3:19047045 n3:4440632 n3:4440635 n3:16083717 n3:26980019 n3:10733525 n3:8787755 n3:12183361 n3:24909886 n3:18353764 n3:9916792 n3:21995959 n3:21999944 n3:12194848 n3:10391247 n3:12629218 n3:22138822 n3:22722868 n3:19822006 n3:23142137 n3:28988015 n3:9393971 n3:23201164 n3:22438566 n3:10934025 n3:18483247 n3:10514384 n3:26863187 n3:11432765 n3:15017003 n3:10037800 n3:19487818 n3:17320548 n3:24089213 n3:21300888 n3:15959515 n3:15959516 n3:24888586 n3:21225631 n3:11955436 n3:26170137 n3:18798982 n3:22190634 n3:22692129 n3:19786015 n3:28279198 n3:15502862 n3:14653469 n3:22810696 n3:17202265 n3:21351269 n3:27571710 n3:18339840 n3:16619050 n3:17868096 n3:26013289 n3:7523487 n3:17615082 n3:23592398 n3:9727977 n3:18325490 n3:11979277 n3:13353477 n3:18296708 n3:29144463 n3:19165146 n3:9295317 n3:11004485 n3:17139285 n3:21376230 n3:18274550 n3:11226292 n3:19487454 n3:17468756 n3:10027409 n3:31057614 n3:23840480 n3:20364088 n3:19403103 n3:20049725 n3:19261089 n3:22166544 n3:25260709 n3:24209998 n3:15829953 n3:8640233 n3:24952462 n3:23273993 n3:11431689 n3:21419747 n3:23382206 n3:19879217 n3:18055444 n3:14749129 n3:27248473 n3:15652704 n3:15778706 n3:22075725 n3:22615920 n3:26457759 n3:17110329 n3:21915337 n3:9697701 n3:15056615 n3:19019766 n3:15542433 n3:16056258 n3:16230531 n3:30207593 n3:22209504 n3:16397499 n3:23835194 n3:10615124 n3:11057903 n3:11595728 n3:19015024 n3:23727861 n3:10521349 n3:17563382 n3:26095047 n3:22770212 n3:18626943 n3:15000148 n3:24332836 n3:12189386 n3:12239569 n3:27079975 n3:19509063 n3:20975679 n3:10751185 n3:23349860 n3:24511467 n3:28273069 n3:8692869 n3:20569694 n3:9407037 n3:22855427 n3:18373705 n3:24157873 n3:9707445 n3:19322650 n3:16554309 n3:8861899 n3:24532713 n3:17267606 n3:24232249 n3:29121666 n3:24825347 n3:17681174 n3:17681175 n3:24060864 n3:18432252 n3:19269367 n3:17237808 n3:1350108 n3:23032722 n3:15372092 n3:22703285 n3:22674330 n3:18414679 n3:30270040 n3:26855967 n3:17237784 n3:27117411 n3:10489374 n3:20513432 n3:9869596 n3:25685828 n3:27429045 n3:11040183 n3:9428790 n3:23989955 n3:16538672 n3:11807034 n3:18400942 n3:15790842 n3:26526724 n3:27413168 n3:18445819 n3:17570220 n3:21383077 n3:15956967 n3:23812904 n3:17625949 n3:17897439 n3:24548059 n3:30118745 n3:24413398 n3:28118628 n3:22895187 n3:11846609 n3:17881565 n3:1459863 n3:23258168 n3:9858536 n3:12051735 n3:13372265 n3:8592733 n3:22271799 n3:24326621 n3:22331131 n3:22844349 n3:22385965 n3:7958926 n3:21727895 n3:23153532 n3:21927002 n3:21217637 n3:20110496 n3:12619811 n3:15716339 n3:16647036 n3:24904831 n3:17377531 n3:17143293 n3:22706340 n3:2100251 n3:18418383 n3:19450592 n3:11752446 n3:29108672 n3:27617575 n3:28802143 n3:28575679 n3:10555149 n3:22385677 n3:18087279 n3:10330456 n3:28482069 n3:21238454 n3:1695712 n3:12839979 n3:19648928 n3:19450512 n3:23398152 n3:9823339 n3:21393571 n3:23635786 n3:20418870 n3:10777564 n3:26645562 n3:19701202 n3:18385740 n3:29587675 n3:14695885 n3:30625324 n3:30259138 n3:1458460 n3:11900252 n3:23290134 n3:15314234 n3:10579974 n3:8259518 n3:19631281 n3:7909785 n3:17290008 n3:21237710 n3:25348713 n3:23478383 n3:22922422 n3:15378062 n3:16258171 n3:30268439 n3:18351289 n3:19059247 n3:22930834 n3:28347989 n3:17245340 n3:30429586 n3:19563763 n3:8552090 n3:11371614 n3:24981363 n3:19273910 n3:15378020 n3:12414734 n3:9646500 n3:18333897 n3:33632315 n3:24191021 n3:11739954 n3:21374063 n3:24247718 n3:28493289 n3:25099011 n3:20651055 n3:22072985 n3:9734398 n3:15096597 n3:18537122 n3:18451032 n3:27880941 n3:15077158 n3:15133499 n3:15998806 n3:24976009 n3:12015971 n3:16954380 n3:17142326 n3:15665104 n3:11201432 n3:27771362 n3:15102707 n3:11326276 n3:11857796 n3:19336570 n3:20417836 n3:22644962 n3:22190486 n3:16199517 n3:1996784 n3:16909111 n3:15289330 n3:14522876 n3:27569216 n3:20488987 n3:23307615 n3:12420222 n3:18536716 n3:21693646 n3:15979579 n3:10201372 n3:27066525 n3:19676123 n3:11429295 n3:21527727 n3:12865297 n3:6297757 n3:23362343 n3:20080688 n3:22393260 n3:21070761 n3:15084848 n3:25865482 n3:19567251 n3:29155957 n3:20887898 n3:12943221 n3:19324043 n3:15132997 n3:16395311 n3:12015290 n3:20383121 n3:15781631 n3:15592505 n3:10883398 n3:32714922 n3:24086078 n3:15469841 n3:10903171 n3:10485468 n3:9311916 n3:21688022 n3:28984791 n3:12094235 n3:19686689 n3:18808327 n3:10769246 n3:8781995 n3:24302456 n3:26009899 n3:18283316 n3:22361729 n3:25308311 n3:21297661 n3:7588051 n3:19681821 n3:15282745 n3:21831298 n3:25007816 n3:20185687 n3:19329995 n3:19130170 n3:15818483 n3:16109882 n3:20395444 n3:22575959 n3:21512138
n2:hasRelevantBibliographicResourceOf: _:vb291653596 _:vb291653597 _:vb291653598 _:vb291653599 _:vb291653592 _:vb291653593 _:vb291653594 _:vb291653595 _:vb291653588 _:vb291653589 _:vb291653590 _:vb291653591 _:vb291653584 _:vb291653585 _:vb291653586 _:vb291653587 _:vb291653580 _:vb291653581 _:vb291653582 _:vb291653583 _:vb291653576 _:vb291653577 _:vb291653578 _:vb291653579 _:vb291653572 _:vb291653573 _:vb291653574 _:vb291653575 _:vb291653568 _:vb291653569 _:vb291653570 _:vb291653571 _:vb291653628 _:vb291653629 _:vb291653630 _:vb291653631 _:vb291653624 _:vb291653625 _:vb291653626 _:vb291653627 _:vb291653620 _:vb291653621 _:vb291653622 _:vb291653623 _:vb291653616 _:vb291653617 _:vb291653618 _:vb291653619 _:vb291653612 _:vb291653613 _:vb291653614 _:vb291653615 _:vb291653608 _:vb291653609 _:vb291653610 _:vb291653611 _:vb291653604 _:vb291653605 _:vb291653606 _:vb291653607 _:vb291653600 _:vb291653601 _:vb291653602 _:vb291653603 _:vb291653532 _:vb291653533 _:vb291653534 _:vb291653535 _:vb291653528 _:vb291653529 _:vb291653530 _:vb291653531 _:vb291653524 _:vb291653525 _:vb291653526 _:vb291653527 _:vb291653520 _:vb291653521 _:vb291653522 _:vb291653523 _:vb291653516 _:vb291653517 _:vb291653518 _:vb291653519 _:vb291653512 _:vb291653513 _:vb291653514 _:vb291653515 _:vb291653508 _:vb291653509 _:vb291653510 _:vb291653511 _:vb291653504 _:vb291653505 _:vb291653506 _:vb291653507 _:vb291653564 _:vb291653565 _:vb291653566 _:vb291653567 _:vb291653560 _:vb291653561 _:vb291653562 _:vb291653563 _:vb291653556 _:vb291653557 _:vb291653558 _:vb291653559 _:vb291653552 _:vb291653553 _:vb291653554 _:vb291653555 _:vb291653548 _:vb291653549 _:vb291653550 _:vb291653551 _:vb291653544 _:vb291653545 _:vb291653546 _:vb291653547 _:vb291653540 _:vb291653541 _:vb291653542 _:vb291653543 _:vb291653536 _:vb291653537 _:vb291653538 _:vb291653539 _:vb291653468 _:vb291653469 _:vb291653470 _:vb291653471 _:vb291653464 _:vb291653465 _:vb291653466 _:vb291653467 _:vb291653460 _:vb291653461 _:vb291653462 _:vb291653463 _:vb291653456 _:vb291653457 _:vb291653458 _:vb291653459 _:vb291653452 _:vb291653453 _:vb291653454 _:vb291653455 _:vb291653448 _:vb291653449 _:vb291653450 _:vb291653451 _:vb291653444 _:vb291653445 _:vb291653446 _:vb291653447 _:vb291653440 _:vb291653441 _:vb291653442 _:vb291653443 _:vb291653500 _:vb291653501 _:vb291653502 _:vb291653503 _:vb291653496 _:vb291653497 _:vb291653498 _:vb291653499 _:vb291653492 _:vb291653493 _:vb291653494 _:vb291653495 _:vb291653488 _:vb291653489 _:vb291653490 _:vb291653491 _:vb291653484 _:vb291653485 _:vb291653486 _:vb291653487 _:vb291653480 _:vb291653481 _:vb291653482 _:vb291653483 _:vb291653476 _:vb291653477 _:vb291653478 _:vb291653479 _:vb291653472 _:vb291653473 _:vb291653474 _:vb291653475 _:vb291653404 _:vb291653405 _:vb291653406 _:vb291653407 _:vb291653400 _:vb291653401 _:vb291653402 _:vb291653403 _:vb291653396 _:vb291653397 _:vb291653398 _:vb291653399 _:vb291653392 _:vb291653393 _:vb291653394 _:vb291653395 _:vb291653388 _:vb291653389 _:vb291653390 _:vb291653391 _:vb291653384 _:vb291653385 _:vb291653386 _:vb291653387 _:vb291653380 _:vb291653381 _:vb291653382 _:vb291653383 _:vb291653376 _:vb291653377 _:vb291653378 _:vb291653379 _:vb291653436 _:vb291653437 _:vb291653438 _:vb291653439 _:vb291653432 _:vb291653433 _:vb291653434 _:vb291653435 _:vb291653428 _:vb291653429 _:vb291653430 _:vb291653431 _:vb291653424 _:vb291653425 _:vb291653426 _:vb291653427 _:vb291653420 _:vb291653421 _:vb291653422 _:vb291653423 _:vb291653416 _:vb291653417 _:vb291653418 _:vb291653419 _:vb291653412 _:vb291653413 _:vb291653414 _:vb291653415 _:vb291653408 _:vb291653409 _:vb291653410 _:vb291653411 _:vb291653340 _:vb291653341 _:vb291653342 _:vb291653343 _:vb291653336 _:vb291653337 _:vb291653338 _:vb291653339 _:vb291653332 _:vb291653333 _:vb291653334 _:vb291653335 _:vb291653328 _:vb291653329 _:vb291653330 _:vb291653331 _:vb291653324 _:vb291653325 _:vb291653326 _:vb291653327 _:vb291653320 _:vb291653321 _:vb291653322 _:vb291653323 _:vb291653316 _:vb291653317 _:vb291653318 _:vb291653319 _:vb291653312 _:vb291653313 _:vb291653314 _:vb291653315 _:vb291653372 _:vb291653373 _:vb291653374 _:vb291653375 _:vb291653368 _:vb291653369 _:vb291653370 _:vb291653371 _:vb291653364 _:vb291653365 _:vb291653366 _:vb291653367 _:vb291653360 _:vb291653361 _:vb291653362 _:vb291653363 _:vb291653356 _:vb291653357 _:vb291653358 _:vb291653359 _:vb291653352 _:vb291653353 _:vb291653354 _:vb291653355 _:vb291653348 _:vb291653349 _:vb291653350 _:vb291653351 _:vb291653344 _:vb291653345 _:vb291653346 _:vb291653347 _:vb291653276 _:vb291653277 _:vb291653278 _:vb291653279 _:vb291653272 _:vb291653273 _:vb291653274 _:vb291653275 _:vb291653268 _:vb291653269 _:vb291653270 _:vb291653271 _:vb291653264 _:vb291653265 _:vb291653266 _:vb291653267 _:vb291653260 _:vb291653261 _:vb291653262 _:vb291653263 _:vb291653256 _:vb291653257 _:vb291653258 _:vb291653259 _:vb291653252 _:vb291653253 _:vb291653254 _:vb291653255 _:vb291653248 _:vb291653249 _:vb291653250 _:vb291653251 _:vb291653308 _:vb291653309 _:vb291653310 _:vb291653311 _:vb291653304 _:vb291653305 _:vb291653306 _:vb291653307 _:vb291653300 _:vb291653301 _:vb291653302 _:vb291653303 _:vb291653296 _:vb291653297 _:vb291653298 _:vb291653299 _:vb291653292 _:vb291653293 _:vb291653294 _:vb291653295 _:vb291653288 _:vb291653289 _:vb291653290 _:vb291653291 _:vb291653284 _:vb291653285 _:vb291653286 _:vb291653287 _:vb291653280 _:vb291653281 _:vb291653282 _:vb291653283 _:vb291653212 _:vb291653213 _:vb291653214 _:vb291653215 _:vb291653208 _:vb291653209 _:vb291653210 _:vb291653211 _:vb291653204 _:vb291653205 _:vb291653206 _:vb291653207 _:vb291653200 _:vb291653201 _:vb291653202 _:vb291653203 _:vb291653196 _:vb291653197 _:vb291653198 _:vb291653199 _:vb291653192 _:vb291653193 _:vb291653194 _:vb291653195 _:vb291653188 _:vb291653189 _:vb291653190 _:vb291653191 _:vb291653184 _:vb291653185 _:vb291653186 _:vb291653187 _:vb291653244 _:vb291653245 _:vb291653246 _:vb291653247 _:vb291653240 _:vb291653241 _:vb291653242 _:vb291653243 _:vb291653236 _:vb291653237 _:vb291653238 _:vb291653239 _:vb291653232 _:vb291653233 _:vb291653234 _:vb291653235 _:vb291653228 _:vb291653229 _:vb291653230 _:vb291653231 _:vb291653224 _:vb291653225 _:vb291653226 _:vb291653227 _:vb291653220 _:vb291653221 _:vb291653222 _:vb291653223 _:vb291653216 _:vb291653217 _:vb291653218 _:vb291653219 _:vb291653180 _:vb291653181 _:vb291653182 _:vb291653183 _:vb291653176 _:vb291653177 _:vb291653178 _:vb291653179 _:vb291653172 _:vb291653173 _:vb291653174 _:vb291653175 _:vb291653168 _:vb291653169 _:vb291653170 _:vb291653171 _:vb291653164 _:vb291653165 _:vb291653166 _:vb291653167 _:vb291653160 _:vb291653161 _:vb291653162 _:vb291653163 _:vb291653156 _:vb291653157 _:vb291653158 _:vb291653159 _:vb291653152 _:vb291653153 _:vb291653154 _:vb291653155 _:vb291653724 _:vb291653720 _:vb291653721 _:vb291653722 _:vb291653723 _:vb291653716 _:vb291653717 _:vb291653718 _:vb291653719 _:vb291653712 _:vb291653713 _:vb291653714 _:vb291653715 _:vb291653708 _:vb291653709 _:vb291653710 _:vb291653711 _:vb291653704 _:vb291653705 _:vb291653706 _:vb291653707 _:vb291653700 _:vb291653701 _:vb291653702 _:vb291653703 _:vb291653696 _:vb291653697 _:vb291653698 _:vb291653699 _:vb291653660 _:vb291653661 _:vb291653662 _:vb291653663 _:vb291653656 _:vb291653657 _:vb291653658 _:vb291653659 _:vb291653652 _:vb291653653 _:vb291653654 _:vb291653655 _:vb291653648 _:vb291653649 _:vb291653650 _:vb291653651 _:vb291653644 _:vb291653645 _:vb291653646 _:vb291653647 _:vb291653640 _:vb291653641 _:vb291653642 _:vb291653643 _:vb291653636 _:vb291653637 _:vb291653638 _:vb291653639 _:vb291653632 _:vb291653633 _:vb291653634 _:vb291653635 _:vb291653692 _:vb291653693 _:vb291653694 _:vb291653695 _:vb291653688 _:vb291653689 _:vb291653690 _:vb291653691 _:vb291653684 _:vb291653685 _:vb291653686 _:vb291653687 _:vb291653680 _:vb291653681 _:vb291653682 _:vb291653683 _:vb291653676 _:vb291653677 _:vb291653678 _:vb291653679 _:vb291653672 _:vb291653673 _:vb291653674 _:vb291653675 _:vb291653668 _:vb291653669 _:vb291653670 _:vb291653671 _:vb291653664 _:vb291653665 _:vb291653666 _:vb291653667
n2:pmcid: PMC0
bibo:doi: 10.1083%2Fjcb.200311021
n8:contains: _:vb780298 _:vb780346 _:vb780336 _:vb780370

Subject Item: _:vb780298
rdf:type: n8:Section
dc:title: introduction
n8:contains: _:vb780300 _:vb780301 _:vb780302 _:vb780303 _:vb780299 _:vb780316 _:vb780317 _:vb780318 _:vb780319 _:vb780312 _:vb780313 _:vb780314 _:vb780315 _:vb780308 _:vb780309 _:vb780310 _:vb780311 _:vb780304 _:vb780305 _:vb780306 _:vb780307 _:vb780332 _:vb780333 _:vb780334 _:vb780335 _:vb780328 _:vb780329 _:vb780330 _:vb780331 _:vb780324 _:vb780325 _:vb780326 _:vb780327 _:vb780320 _:vb780321 _:vb780322 _:vb780323

Subject Item: _:vb780299
rdf:type: n2:Context
rdf:value: In the small intestine, a fourth cell type, the Paneth cells, migrates downward and settles at the bottom of the crypts as terminally differentiated cells (Potten and Moeffler, >>1990<<; Stappenbeck et al., 1998).
n2:mentions: n3:2100251

Subject Item: _:vb780300
rdf:type: n2:Context
rdf:value: In the small intestine, a fourth cell type, the Paneth cells, migrates downward and settles at the bottom of the crypts as terminally differentiated cells (Potten and Moeffler, 1990; Stappenbeck et al., >>1998<<).
n2:mentions: n3:9914172

Subject Item: _:vb780301
rdf:type: n2:Context
rdf:value: Interaction with β-catenin activates the TCF/LEF transcription factors, resulting in transcription of target genes (Brantjes et al., >>2002<<). In the intestine, the Wnt signaling pathway has been implicated in the regulation of the proliferation/differentiation balance (van de Wetering et al., 2002). Consistent with this, no proliferation can be detected, and all epithelial
n2:mentions: n3:11934263

Subject Item: _:vb780302
rdf:type: n2:Context
rdf:value: In the intestine, the Wnt signaling pathway has been implicated in the regulation of the proliferation/differentiation balance (van de Wetering et al., >>2002<<). Consistent with this, no proliferation can be detected, and all epithelial cells appear differentiated, in the intestine of mice null for TCF4, the main Wnt pathway transcription factor in the intestinal epithelium (Korinek et al.,
n2:mentions: n3:12408868

Subject Item: _:vb780303
rdf:type: n2:Context
rdf:value: Consistent with this, no proliferation can be detected, and all epithelial cells appear differentiated, in the intestine of mice null for TCF4, the main Wnt pathway transcription factor in the intestinal epithelium (Korinek et al., >>1998<<). The Wnt pathway also regulates the expression of the Eph/Ephrin surface molecules, responsible for the ordered positioning of epithelial cells along the crypt-villus axis (Batlle et al., 2002).
n2:mentions: n3:9697701

Subject Item: _:vb780304
rdf:type: n2:Context
rdf:value: The Wnt pathway also regulates the expression of the Eph/Ephrin surface molecules, responsible for the ordered positioning of epithelial cells along the crypt-villus axis (Batlle et al., >>2002<<). In addition, Wnt signals control the differentiation of the secretory cell lineage of the epithelium, because overexpression of the Wnt-pathway inhibitor Dickkopf1 blocks differentiation of the Paneth, goblet, and enteroendocrine cell
n2:mentions: n3:12408869

Subject Item: _:vb780305
rdf:type: n2:Context
rdf:value: control the differentiation of the secretory cell lineage of the epithelium, because overexpression of the Wnt-pathway inhibitor Dickkopf1 blocks differentiation of the Paneth, goblet, and enteroendocrine cell types (Pinto et al., >>2003<<). Finally, mutations in components of the Wnt pathway, including the tumor suppressor APC and the multifunctional β-catenin protein, are found in the vast majority of colon cancers (Morin et al., 1997).
n2:mentions: n3:12865297

Subject Item: _:vb780306
rdf:type: n2:Context
rdf:value: Finally, mutations in components of the Wnt pathway, including the tumor suppressor APC and the multifunctional β-catenin protein, are found in the vast majority of colon cancers (Morin et al., >>1997<<). Such mutations result in stabilization of β-catenin, which then continuously interacts with TCF4, leading to constitutive activation of target genes (Korinek et al., 1997). Moreover, targeted mutations of APC or β-catenin are sufficient
n2:mentions: n3:9065402

Subject Item: _:vb780307
rdf:type: n2:Context
rdf:value: Such mutations result in stabilization of β-catenin, which then continuously interacts with TCF4, leading to constitutive activation of target genes (Korinek et al., >>1997<<). Moreover, targeted mutations of APC or β-catenin are sufficient to initiate tumorigenesis in the mouse (Fodde et al., 1994; Shibata et al., 1997; Harada et al., 1999), highlighting the importance of the Wnt pathway in the development of
n2:mentions: n3:9065401

Subject Item: _:vb780308
rdf:type: n2:Context
rdf:value: Moreover, targeted mutations of APC or β-catenin are sufficient to initiate tumorigenesis in the mouse (Fodde et al., >>1994<<; Shibata et al., 1997; Harada et al., 1999), highlighting the importance of the Wnt pathway in the development of cancer.
n2:mentions: n3:8090754

Subject Item: _:vb780309
rdf:type: n2:Context
rdf:value: Moreover, targeted mutations of APC or β-catenin are sufficient to initiate tumorigenesis in the mouse (Fodde et al., 1994; Shibata et al., >>1997<<; Harada et al., 1999), highlighting the importance of the Wnt pathway in the development of cancer.
n2:mentions: n3:9311916

Subject Item: _:vb780310
rdf:type: n2:Context
rdf:value: Moreover, targeted mutations of APC or β-catenin are sufficient to initiate tumorigenesis in the mouse (Fodde et al., 1994; Shibata et al., 1997; Harada et al., >>1999<<), highlighting the importance of the Wnt pathway in the development of cancer.
n2:mentions: n3:10545105

Subject Item: _:vb780311
rdf:type: n2:Context
rdf:value: Similarly to TCFs, SOX proteins have been widely implicated in the establishment of cell multipotency (Avilion et al., >>2003<<; Kim et al., 2003), cell commitment (Mori-Akiyama et al., 2003; Stolt et al., 2003), and differentiation (Kamachi et al., 2000; Stolt et al., 2002).
n2:mentions: n3:12514105

Subject Item: _:vb780312
rdf:type: n2:Context
rdf:value: Similarly to TCFs, SOX proteins have been widely implicated in the establishment of cell multipotency (Avilion et al., 2003; Kim et al., >>2003<<), cell commitment (Mori-Akiyama et al., 2003; Stolt et al., 2003), and differentiation (Kamachi et al., 2000; Stolt et al., 2002).
n2:mentions: n3:12691661

Subject Item: _:vb780313
rdf:type: n2:Context
rdf:value: Similarly to TCFs, SOX proteins have been widely implicated in the establishment of cell multipotency (Avilion et al., 2003; Kim et al., 2003), cell commitment (Mori-Akiyama et al., >>2003<<; Stolt et al., 2003), and differentiation (Kamachi et al., 2000; Stolt et al., 2002).
n2:mentions: n3:12878728

Subject Item: _:vb780314
rdf:type: n2:Context
rdf:value: Similarly to TCFs, SOX proteins have been widely implicated in the establishment of cell multipotency (Avilion et al., 2003; Kim et al., 2003), cell commitment (Mori-Akiyama et al., 2003; Stolt et al., >>2003<<), and differentiation (Kamachi et al., 2000; Stolt et al., 2002).
n2:mentions: n3:12842915

Subject Item: _:vb780315
rdf:type: n2:Context
rdf:value: TCFs, SOX proteins have been widely implicated in the establishment of cell multipotency (Avilion et al., 2003; Kim et al., 2003), cell commitment (Mori-Akiyama et al., 2003; Stolt et al., 2003), and differentiation (Kamachi et al., >>2000<<; Stolt et al., 2002). Here, we screened the intestine epithelium for expressed SOX genes to investigate the possibility of a functional link with the related Tcf factors.
n2:mentions: n3:10729834

Subject Item: _:vb780316
rdf:type: n2:Context
rdf:value: have been widely implicated in the establishment of cell multipotency (Avilion et al., 2003; Kim et al., 2003), cell commitment (Mori-Akiyama et al., 2003; Stolt et al., 2003), and differentiation (Kamachi et al., 2000; Stolt et al., >>2002<<). Here, we screened the intestine epithelium for expressed SOX genes to investigate the possibility of a functional link with the related Tcf factors.
n2:mentions: n3:11799060

Subject Item: _:vb780317
rdf:type: n2:Context
rdf:value: SOX9 function is best known for its essential roles in chondrogenesis (Foster et al., >>1994<<; Wagner et al., 1994; Wright et al., 1995; Bi et al., 1999, 2001) and the development of the male gonad (Foster et al., 1994; Wagner et al., 1994; Kent et al., 1996; Südbeck et al., 1996).
n2:mentions: n3:7990924

Subject Item: _:vb780318
rdf:type: n2:Context
rdf:value: SOX9 function is best known for its essential roles in chondrogenesis (Foster et al., 1994; Wagner et al., >>1994<<; Wright et al., 1995; Bi et al., 1999, 2001) and the development of the male gonad (Foster et al., 1994; Wagner et al., 1994; Kent et al., 1996; Südbeck et al., 1996).
n2:mentions: n3:8001137

Subject Item: _:vb780319
rdf:type: n2:Context
rdf:value: SOX9 function is best known for its essential roles in chondrogenesis (Foster et al., 1994; Wagner et al., 1994; Wright et al., >>1995<<; Bi et al., 1999, 2001) and the development of the male gonad (Foster et al., 1994; Wagner et al., 1994; Kent et al., 1996; Südbeck et al., 1996).
n2:mentions: n3:7704017

Subject Item: _:vb780320
rdf:type: n2:Context
rdf:value: SOX9 function is best known for its essential roles in chondrogenesis (Foster et al., 1994; Wagner et al., 1994; Wright et al., 1995; Bi et al., >>1999<<, 2001) and the development of the male gonad (Foster et al., 1994; Wagner et al., 1994; Kent et al., 1996; Südbeck et al., 1996).
n2:mentions: n3:10319868

Subject Item: _:vb780321
rdf:type: n2:Context
rdf:value: SOX9 function is best known for its essential roles in chondrogenesis (Foster et al., 1994; Wagner et al., 1994; Wright et al., 1995; Bi et al., 1999, >>2001<<) and the development of the male gonad (Foster et al., 1994; Wagner et al., 1994; Kent et al., 1996; Südbeck et al., 1996).
n2:mentions: n3:11371614

Subject Item: _:vb780322
rdf:type: n2:Context
rdf:value: SOX9 function is best known for its essential roles in chondrogenesis (Foster et al., 1994; Wagner et al., 1994; Wright et al., 1995; Bi et al., 1999, 2001) and the development of the male gonad (Foster et al., >>1994<<; Wagner et al., 1994; Kent et al., 1996; Südbeck et al., 1996). SOX9 is also involved in the development of the neural crest (Spokony et al., 2002) and of the spinal cord glial cells (Stolt et al., 2003).
n2:mentions: n3:7990924

Subject Item: _:vb780323
rdf:type: n2:Context
rdf:value: SOX9 function is best known for its essential roles in chondrogenesis (Foster et al., 1994; Wagner et al., 1994; Wright et al., 1995; Bi et al., 1999, 2001) and the development of the male gonad (Foster et al., 1994; Wagner et al., >>1994<<; Kent et al., 1996; Südbeck et al., 1996). SOX9 is also involved in the development of the neural crest (Spokony et al., 2002) and of the spinal cord glial cells (Stolt et al., 2003).
n2:mentions: n3:8001137

Subject Item: _:vb780324
rdf:type: n2:Context
rdf:value: best known for its essential roles in chondrogenesis (Foster et al., 1994; Wagner et al., 1994; Wright et al., 1995; Bi et al., 1999, 2001) and the development of the male gonad (Foster et al., 1994; Wagner et al., 1994; Kent et al., >>1996<<; Südbeck et al., 1996). SOX9 is also involved in the development of the neural crest (Spokony et al., 2002) and of the spinal cord glial cells (Stolt et al., 2003).
n2:mentions: n3:8787755

Subject Item: _:vb780325
rdf:type: n2:Context
rdf:value: roles in chondrogenesis (Foster et al., 1994; Wagner et al., 1994; Wright et al., 1995; Bi et al., 1999, 2001) and the development of the male gonad (Foster et al., 1994; Wagner et al., 1994; Kent et al., 1996; Südbeck et al., >>1996<<). SOX9 is also involved in the development of the neural crest (Spokony et al., 2002) and of the spinal cord glial cells (Stolt et al., 2003).
n2:mentions: n3:8640233

Subject Item: _:vb780326
rdf:type: n2:Context
rdf:value: SOX9 is also involved in the development of the neural crest (Spokony et al., >>2002<<) and of the spinal cord glial cells (Stolt et al., 2003).
n2:mentions: n3:11807034

Subject Item: _:vb780327
rdf:type: n2:Context
rdf:value: SOX9 is also involved in the development of the neural crest (Spokony et al., 2002) and of the spinal cord glial cells (Stolt et al., >>2003<<). Strikingly, SOX9 controls the transcription of target genes which are specific for each process: in chondrogenesis, it regulates the cartilage specific genes Col2a1 (Bell et al., 1997; Lefebvre et al., 1997; Bi et al., 1999), Col11a2
n2:mentions: n3:12842915

Subject Item: _:vb780328
rdf:type: n2:Context
rdf:value: Strikingly, SOX9 controls the transcription of target genes which are specific for each process: in chondrogenesis, it regulates the cartilage specific genes Col2a1 (Bell et al., >>1997<<; Lefebvre et al., 1997; Bi et al., 1999), Col11a2 (Bridgewater et al., 1998), Aggrecan (Sekiya et al., 2000), and campomelic dysplasia (CD)–RAP (Xie et al., 1999).
n2:mentions: n3:9171829

Subject Item: _:vb780329
rdf:type: n2:Context
rdf:value: Strikingly, SOX9 controls the transcription of target genes which are specific for each process: in chondrogenesis, it regulates the cartilage specific genes Col2a1 (Bell et al., 1997; Lefebvre et al., >>1997<<; Bi et al., 1999), Col11a2 (Bridgewater et al., 1998), Aggrecan (Sekiya et al., 2000), and campomelic dysplasia (CD)–RAP (Xie et al., 1999).
n2:mentions: n3:9121483

Subject Item: _:vb780330
rdf:type: n2:Context
rdf:value: Strikingly, SOX9 controls the transcription of target genes which are specific for each process: in chondrogenesis, it regulates the cartilage specific genes Col2a1 (Bell et al., 1997; Lefebvre et al., 1997; Bi et al., >>1999<<), Col11a2 (Bridgewater et al., 1998), Aggrecan (Sekiya et al., 2000), and campomelic dysplasia (CD)–RAP (Xie et al., 1999).
n2:mentions: n3:10319868

Subject Item: _:vb780331
rdf:type: n2:Context
rdf:value: the transcription of target genes which are specific for each process: in chondrogenesis, it regulates the cartilage specific genes Col2a1 (Bell et al., 1997; Lefebvre et al., 1997; Bi et al., 1999), Col11a2 (Bridgewater et al., >>1998<<), Aggrecan (Sekiya et al., 2000), and campomelic dysplasia (CD)–RAP (Xie et al., 1999).
n2:mentions: n3:9614107

Subject Item: _:vb780332
rdf:type: n2:Context
rdf:value: genes which are specific for each process: in chondrogenesis, it regulates the cartilage specific genes Col2a1 (Bell et al., 1997; Lefebvre et al., 1997; Bi et al., 1999), Col11a2 (Bridgewater et al., 1998), Aggrecan (Sekiya et al., >>2000<<), and campomelic dysplasia (CD)–RAP (Xie et al., 1999). During male gonad development, it controls the expression of the anti-Müllerrian hormone gene (de Santa Barbara et al., 1998).
n2:mentions: n3:10753864

Subject Item: _:vb780333
rdf:type: n2:Context
rdf:value: it regulates the cartilage specific genes Col2a1 (Bell et al., 1997; Lefebvre et al., 1997; Bi et al., 1999), Col11a2 (Bridgewater et al., 1998), Aggrecan (Sekiya et al., 2000), and campomelic dysplasia (CD)–RAP (Xie et al., >>1999<<). During male gonad development, it controls the expression of the anti-Müllerrian hormone gene (de Santa Barbara et al., 1998).
n2:mentions: n3:10320524

Subject Item: _:vb780334
rdf:type: n2:Context
rdf:value: During male gonad development, it controls the expression of the anti-Müllerrian hormone gene (de Santa Barbara et al., >>1998<<). In the neural crest, the expression of the transcription factor Slug depends on SOX9 (Spokony et al., 2002), whereas SOX9 target genes remain to be identified in the spinal cord.
n2:mentions: n3:9774680

Subject Item: _:vb780335
rdf:type: n2:Context
rdf:value: In the neural crest, the expression of the transcription factor Slug depends on SOX9 (Spokony et al., >>2002<<), whereas SOX9 target genes remain to be identified in the spinal cord.
n2:mentions: n3:11807034

Subject Item: _:vb780336
rdf:type: n8:Section
dc:title: materials and methods
n8:contains: _:vb780340 _:vb780341 _:vb780342 _:vb780343 _:vb780337 _:vb780338 _:vb780339 _:vb780344 _:vb780345

Subject Item: _:vb780337
rdf:type: n2:Context
rdf:value: NH2-terminally flagged wild-type and COOH-terminally truncated SOX9-pcDNA expression constructs have been described previously (Südbeck et al., >>1996<<; de Santa Barbara et al., 1998). The antisense SOX9 expression construct was generated by cloning the BamHI–EcoRI fragment containing the SOX9 ORF from SOX9-pcDNA into the same restriction sites of pIRESneo (CLONTECH Laboratories, Inc.
n2:mentions: n3:8640233

Subject Item: _:vb780338
rdf:type: n2:Context
rdf:value: NH2-terminally flagged wild-type and COOH-terminally truncated SOX9-pcDNA expression constructs have been described previously (Südbeck et al., 1996; de Santa Barbara et al., >>1998<<). The antisense SOX9 expression construct was generated by cloning the BamHI–EcoRI fragment containing the SOX9 ORF from SOX9-pcDNA into the same restriction sites of pIRESneo (CLONTECH Laboratories, Inc.
n2:mentions: n3:9774680

Subject Item: _:vb780339
rdf:type: n2:Context
rdf:value: NH2-truncated TCF4 (ΔN-TCF4 dominant negative) has been described previously (van de Wetering et al., >>2002<<) and was provided by B.
n2:mentions: n3:12408868

Subject Item: _:vb780340
rdf:type: n2:Context
rdf:value: The SOX9-VP16 (Kamachi et al., >>1999<<) was provided by H. Kondoh (Institute for Molecular and Cellular Biology, Osaka University, Osaka, Japan), and the MUC-2-luciferase reporter (Yamamoto et al., 2003) was a gift from Y.
n2:mentions: n3:9858536

Subject Item: _:vb780341
rdf:type: n2:Context
rdf:value: Kondoh (Institute for Molecular and Cellular Biology, Osaka University, Osaka, Japan), and the MUC-2-luciferase reporter (Yamamoto et al., >>2003<<) was a gift from Y.
n2:mentions: n3:12559945

Subject Item: _:vb780342
rdf:type: n2:Context
rdf:value: The CDX-2 promoter reporter constructs were published previously (Lorentz et al., >>1999<<).
n2:mentions: n3:9926923

Subject Item: _:vb780343
rdf:type: n2:Context
rdf:value: Stably transfected LS174T cell lines with inducible ΔNTCF4 have been described previously (van de Wetering et al., >>2002<<). HT29-16E human colorectal carcinoma cells were given by C. Laboisse (INSERM U539, Nantes, France). The T-RexTM system (Invitrogen) was used for the generation of stable SOX9-inducible HT29-16E cells. In brief, tetracycline-inducible
n2:mentions: n3:12408868

Subject Item: _:vb780344
rdf:type: n2:Context
rdf:value: The TCF4 K.O. mouse has been described previously (Korinek et al., >>1998<<). For immunofluorescence experiments, nuclei were stained with Hoechst (H33258; Sigma-Aldrich).
n2:mentions: n3:9697701

Subject Item: _:vb780345
rdf:type: n2:Context
rdf:value: The SOX9 antibody has been described previously (de Santa Barbara et al., >>1998<<). The MUC2 antibody (1:1,000) was provided by I. van Seuningen (INSERM U560, Lille, France).
n2:mentions: n3:9774680

Subject Item: _:vb780346
rdf:type: n8:Section
dc:title: results
n8:contains: _:vb780348 _:vb780349 _:vb780350 _:vb780351 _:vb780347 _:vb780364 _:vb780365 _:vb780366 _:vb780367 _:vb780360 _:vb780361 _:vb780362 _:vb780363 _:vb780356 _:vb780357 _:vb780358 _:vb780359 _:vb780352 _:vb780353 _:vb780354 _:vb780355 _:vb780368 _:vb780369

Subject Item: _:vb780347
rdf:type: n2:Context
rdf:value: RT-PCR was performed with mouse neonate intestine, using degenerate oligonucleotide primers (Cremazy et al., >>1998<<). The amplified products were cloned and sequenced, leading to the identification of SOX3, SOX4, SOX5, SOX7, SOX9, and SOX18.
n2:mentions: n3:9827568

Subject Item: _:vb780348
rdf:type: n2:Context
rdf:value: As the subcellular localization of SOX9 is regulated in some structures, such as the gonad (Smith and Koopman, >>2004<<), we tested whether the intestinal epithelium cytoplasmic staining was specific, using Western blot analysis of nuclear and cytoplasmic subcellular fractions of mouse intestine epithelial cells and of human cultured HT29-16E cells.
n2:mentions: n3:14698613

Subject Item: _:vb780349
rdf:type: n2:Context
rdf:value: The SOX9 expression pattern strikingly matches the domain of the epithelial cells stimulated by Wnt molecules, where nuclear β-catenin can interact with TCF4 to activate transcription (van de Wetering et al., >>2002<<). Although the Wnt pathway controls multiple aspects of intestine epithelium physiology, little is known about downstream transcription factors.
n2:mentions: n3:12408868

Subject Item: _:vb780350
rdf:type: n2:Context
rdf:value: We first tested SOX9 expression in human colon cancer–derived cell lines containing activating mutations of components of the Wnt pathway, which result in constitutive expression of β-catenin/TCF4 target genes (Korinek et al., >>1997<<). In all the colon cancer cell lines we tested (DLD-1, LS174T, SW480, TC-7, and HT29), SOX9 mRNA (not depicted) and protein were strongly expressed (Fig.
n2:mentions: n3:9065401

Subject Item: _:vb780351
rdf:type: n2:Context
rdf:value: Such cells can be identified because they contain cytoplasmic and nuclear β-catenin (Korinek et al., >>1997<<). When we stained serial sections for β-catenin, it was clear that the same structures that strongly expressed SOX9 also contain cytoplasmic and nuclear β-catenin (Fig. 2, c and d). This result again correlates SOX9 expression with
n2:mentions: n3:9065401

Subject Item: _:vb780352
rdf:type: n2:Context
rdf:value: NH2-terminally deleted mutant lacks the β-catenin-interaction domain and has been shown to interfere with the activity of the endogenous, constitutively active, β-catenin–TCF4 complex present in these cells (van de Wetering et al., >>2002<<). Cells were transfected with either the ΔNTCF4 or a mock GFP expression construct and the endogenous SOX9 protein expression was monitored by immunofluorescence.
n2:mentions: n3:12408868

Subject Item: _:vb780353
rdf:type: n2:Context
rdf:value: proteins, we overexpressed the cytoplasmic domain of E-cadherin (cyt-E-cadherin), which has been reported to sequester signaling-competent β-catenin, thus abrogating the β-catenin–TCF4 transcriptional activity (Gottardi et al., >>2001<<; Simcha et al., 2001).
n2:mentions: n3:11381089

Subject Item: _:vb780354
rdf:type: n2:Context
rdf:value: the cytoplasmic domain of E-cadherin (cyt-E-cadherin), which has been reported to sequester signaling-competent β-catenin, thus abrogating the β-catenin–TCF4 transcriptional activity (Gottardi et al., 2001; Simcha et al., >>2001<<). As expected, overexpression of a GFP–cyt-E-cadherin construct in LS174T cells resulted in a strong decrease of nuclear β-catenin staining, which then colocalized with the GFP–cyt-E-cadherin fusion in a perinuclear pattern (Fig.
n2:mentions: n3:11294915

Subject Item: _:vb780355
rdf:type: n2:Context
rdf:value: We found that this regulation of SOX9 occurs at the RNA level using LS174T human colon carcinoma cells stably transfected with an inducible ΔNTCF4 construct (van de Wetering et al., >>2002<<). As noted above, LS174T cells express high levels of endogenous SOX9 mRNA and protein.
n2:mentions: n3:12408868

Subject Item: _:vb780356
rdf:type: n2:Context
rdf:value: The Wnt–β-catenin–TCF4 pathway is necessary for the maintenance of a functional crypt-villus axis in the mouse intestinal epithelium (Pinto et al., >>2003<<). The gene knockout of its transcriptional effector, TCF4, leads to the loss of the proliferative compartment of the epithelium.
n2:mentions: n3:12865297

Subject Item: _:vb780357
rdf:type: n2:Context
rdf:value: As a consequence, TCF4 null mice die perinatally (Korinek et al., >>1998<<). As the Wnt signaling pathway is essential for SOX9 expression in cultured cells, we expected that SOX9 expression would be disrupted in the intestinal epithelium of TCF4 null mice.
n2:mentions: n3:9697701

Subject Item: _:vb780358
rdf:type: n2:Context
rdf:value: We then screened by RT-PCR a panel of previously reported Wnt–β-catenin–TCF4-regulated genes (van de Wetering et al., >>2002<<). This led to the identification of both SOX9-dependent and SOX9-independent Wnt target genes (Fig. 5), indicating branching of the Wnt response, which might explain how the Wnt pathway can exert a wide spectrum of cellular effects.
n2:mentions: n3:12408868

Subject Item: _:vb780359
rdf:type: n2:Context
rdf:value: CDX1/-2 genes, both homologues of the Drosophila homeobox Caudal gene (Duprey et al., >>1988<<; Suh et al., 1994), exemplified such branching.
n2:mentions: n3:2905686

Subject Item: _:vb780360
rdf:type: n2:Context
rdf:value: CDX1/-2 genes, both homologues of the Drosophila homeobox Caudal gene (Duprey et al., 1988; Suh et al., >>1994<<), exemplified such branching.
n2:mentions: n3:7935448

Subject Item: _:vb780361
rdf:type: n2:Context
rdf:value: In the intestinal epithelium, the CDX1 transcription factor is mostly expressed in the crypts whereas CDX2 is mostly active on the villi (Subramanian et al., >>1998<<; Silberg et al., 2000).
n2:mentions: n3:9921649

Subject Item: _:vb780362
rdf:type: n2:Context
rdf:value: In the intestinal epithelium, the CDX1 transcription factor is mostly expressed in the crypts whereas CDX2 is mostly active on the villi (Subramanian et al., 1998; Silberg et al., >>2000<<). Both genes are thought to be important for the antero-posterior patterning of the intestinal epithelium and in defining patterns of proliferation and differentiation along the crypt-villus axis (Silberg et al., 2000). CDX1/-2 are,
n2:mentions: n3:11040183

Subject Item: _:vb780363
rdf:type: n2:Context
rdf:value: Both genes are thought to be important for the antero-posterior patterning of the intestinal epithelium and in defining patterns of proliferation and differentiation along the crypt-villus axis (Silberg et al., >>2000<<). CDX1/-2 are, respectively, positively and negatively regulated by the Wnt pathway. Indeed, coculture experiments, as well as loss of CDX1 expression in the gut of TCF4-deficient mice, led to the conclusion that CDX1 is a target of the
n2:mentions: n3:11040183

Subject Item: _:vb780364
rdf:type: n2:Context
rdf:value: Indeed, coculture experiments, as well as loss of CDX1 expression in the gut of TCF4-deficient mice, led to the conclusion that CDX1 is a target of the Wnt–β-catenin–TCF4 pathway (Lickert et al., >>2000<<; Ikeya and Takada, 2001).
n2:mentions: n3:10934025

Subject Item: _:vb780365
rdf:type: n2:Context
rdf:value: Indeed, coculture experiments, as well as loss of CDX1 expression in the gut of TCF4-deficient mice, led to the conclusion that CDX1 is a target of the Wnt–β-catenin–TCF4 pathway (Lickert et al., 2000; Ikeya and Takada, >>2001<<). On the other hand, APC up-regulates CDX2 (da Costa et al., 1999), although the signaling pathway downstream of APC has not yet been elucidated. In our experiment, CDX1 expression was not altered by gain/loss of SOX9 function in LS174T
n2:mentions: n3:11335109

Subject Item: _:vb780366
rdf:type: n2:Context
rdf:value: On the other hand, APC up-regulates CDX2 (da Costa et al., >>1999<<), although the signaling pathway downstream of APC has not yet been elucidated.
n2:mentions: n3:10490837

Subject Item: _:vb780367
rdf:type: n2:Context
rdf:value: We conclude that SOX9 is involved in the regulation of CDX2 but not CDX1, which is consistent with previous reports showing that CDX1 is a direct transcriptional target of the β-catenin–TCF4 complex (Lickert et al., >>2000<<). c-Myc has also been described as a direct β-catenin–TCF4 target (He et al., 1998), but its expression level is not altered neither by SOX9 gain/loss of function (Fig. 5). Several SOX9-dependent genes are down-regulated in cells
n2:mentions: n3:10934025

Subject Item: _:vb780368
rdf:type: n2:Context
rdf:value: c-Myc has also been described as a direct β-catenin–TCF4 target (He et al., >>1998<<), but its expression level is not altered neither by SOX9 gain/loss of function (Fig.
n2:mentions: n3:9727977

Subject Item: _:vb780369
rdf:type: n2:Context
rdf:value: In addition to CDX2 and its target gene MUC2 (Yamamoto et al., >>2003<<; Figs. 5 and 6 a), there was slight but reproducible SOX9-dependent down-regulation of genes encoding the differentiation markers Fabp-i and Galectin-4 (not depicted).
n2:mentions: n3:12559945

Subject Item: _:vb780370
rdf:type: n8:Section
dc:title: discussion
n8:contains: _:vb780416 _:vb780417 _:vb780418 _:vb780419 _:vb780396 _:vb780397 _:vb780398 _:vb780399 _:vb780392 _:vb780393 _:vb780394 _:vb780395 _:vb780388 _:vb780389 _:vb780390 _:vb780391 _:vb780384 _:vb780385 _:vb780386 _:vb780387 _:vb780412 _:vb780413 _:vb780414 _:vb780415 _:vb780408 _:vb780409 _:vb780410 _:vb780411 _:vb780404 _:vb780405 _:vb780406 _:vb780407 _:vb780400 _:vb780401 _:vb780402 _:vb780403 _:vb780380 _:vb780381 _:vb780382 _:vb780383 _:vb780376 _:vb780377 _:vb780378 _:vb780379 _:vb780372 _:vb780373 _:vb780374 _:vb780375 _:vb780371

Subject Item: _:vb780371
rdf:type: n2:Context
rdf:value: SOX9 was first described as the gene responsible, when heterozygously mutated, for the skeletal malformation syndrome, CD, which is sometimes associated with XY sex reversal (Foster et al., >>1994<<; Wagner et al., 1994). Of note, no intestinal epithelium defect has been reported to date in CD patients, indicating that SOX9 haploinsufficiency may not be critical in this tissue.
n2:mentions: n3:7990924

Subject Item: _:vb780372
rdf:type: n2:Context
rdf:value: SOX9 was first described as the gene responsible, when heterozygously mutated, for the skeletal malformation syndrome, CD, which is sometimes associated with XY sex reversal (Foster et al., 1994; Wagner et al., >>1994<<). Of note, no intestinal epithelium defect has been reported to date in CD patients, indicating that SOX9 haploinsufficiency may not be critical in this tissue.
n2:mentions: n3:8001137

Subject Item: _:vb780373
rdf:type: n2:Context
rdf:value: More recently, SOX9 was found to be essential for the development of the neural crests and the central nervous system (Xie et al., >>1999<<; Spokony et al., 2002; Mori-Akiyama et al., 2003).
n2:mentions: n3:10320524

Subject Item: _:vb780374
rdf:type: n2:Context
rdf:value: More recently, SOX9 was found to be essential for the development of the neural crests and the central nervous system (Xie et al., 1999; Spokony et al., >>2002<<; Mori-Akiyama et al., 2003).
n2:mentions: n3:11807034

Subject Item: _:vb780375
rdf:type: n2:Context
rdf:value: More recently, SOX9 was found to be essential for the development of the neural crests and the central nervous system (Xie et al., 1999; Spokony et al., 2002; Mori-Akiyama et al., >>2003<<). Here, we report that SOX9 is also expressed in the intestinal epithelium. In this highly organized structure, the SOX9 protein is only expressed in the lower third of the crypts of Lieberkühn, in both the small intestine and colon.
n2:mentions: n3:12878728

Subject Item: _:vb780376
rdf:type: n2:Context
rdf:value: Paneth cells, which occupy the bottom of the small intestine crypts, beneath the cells constituting the proliferative compartment, are postmitotic, fully differentiated cells (Cheng, >>1974<<). Thus, SOX9 is expressed in proliferative cells, which probably include the stem cells, as well as in the terminally differentiated Paneth cells. This suggests that SOX9 expression is not restricted either to a single cell type or to the
n2:mentions: n3:4440633

Subject Item: _:vb780377
rdf:type: n2:Context
rdf:value: Rather, it corresponds to a location, the bottom of the crypt, which is also considered to be the cellular “niche” of the epithelium, where cells contain nuclear β-catenin in response to Wnt signaling (Batlle et al., >>2002<<; van de Wetering et al., 2002).
n2:mentions: n3:12408869

Subject Item: _:vb780378
rdf:type: n2:Context
rdf:value: to a location, the bottom of the crypt, which is also considered to be the cellular “niche” of the epithelium, where cells contain nuclear β-catenin in response to Wnt signaling (Batlle et al., 2002; van de Wetering et al., >>2002<<).
n2:mentions: n3:12408868

Subject Item: _:vb780379
rdf:type: n2:Context
rdf:value: This fragment did not contain a canonical TCF binding sequence (ATCAAAGG), but contained several noncanonical TCF binding sites, such as described, for instance, in the Siamois (Brannon et al., >>1997<<) and Cyclin D1 (Tetsu and McCormick, 1999) promoters.
n2:mentions: n3:9308964

Subject Item: _:vb780380
rdf:type: n2:Context
rdf:value: fragment did not contain a canonical TCF binding sequence (ATCAAAGG), but contained several noncanonical TCF binding sites, such as described, for instance, in the Siamois (Brannon et al., 1997) and Cyclin D1 (Tetsu and McCormick, >>1999<<) promoters. However, the basal luciferase activity driven by this 2.6-kb SOX9 promoter fragment in LS174T colon carcinoma cells was not modulated by cotransfected ΔNTCF4 (unpublished data).
n2:mentions: n3:10201372

Subject Item: _:vb780381
rdf:type: n2:Context
rdf:value: Indeed, although this promoter has been poorly characterized, scattered regulatory enhancer elements have been detected up to 1 megabase upstream of the human SOX9 transcriptional unit (Wunderle et al., >>1998<<; Bishop et al., 2000).
n2:mentions: n3:9724758

Subject Item: _:vb780382
rdf:type: n2:Context
rdf:value: Indeed, although this promoter has been poorly characterized, scattered regulatory enhancer elements have been detected up to 1 megabase upstream of the human SOX9 transcriptional unit (Wunderle et al., 1998; Bishop et al., >>2000<<). We performed in silico screening of the genomic region situated from 200 kb upstream to 100 kb downstream of the SOX9 transcriptional unit for putative canonical TCF binding sites. Although several putative sites were identified, the
n2:mentions: n3:11101852

Subject Item: _:vb780383
rdf:type: n2:Context
rdf:value: In an alternative model, the Wnt regulation of SOX9 might involve one or several intermediate transcription factors, such as CDX-1 or c-MYC, which have already been described as direct Wnt targets (He et al., >>1998<<; Lickert et al., 2000) and are not regulated by SOX9 in our RT-PCR experiment.
n2:mentions: n3:9727977

Subject Item: _:vb780384
rdf:type: n2:Context
rdf:value: In an alternative model, the Wnt regulation of SOX9 might involve one or several intermediate transcription factors, such as CDX-1 or c-MYC, which have already been described as direct Wnt targets (He et al., 1998; Lickert et al., >>2000<<) and are not regulated by SOX9 in our RT-PCR experiment.
n2:mentions: n3:10934025

Subject Item: _:vb780385
rdf:type: n2:Context
rdf:value: A study of the transcriptional response of NCCIT human embryonal carcinoma cells to the Wnt-3a signal identified SOX9 as one of the genes which was up-regulated upon Wnt-3a signaling (Willert et al., >>2002<<). Such Wnt-regulation of SOX9 thus might also exist in additional structures where SOX9 expression has been reported.
n2:mentions: n3:12095419

Subject Item: _:vb780386
rdf:type: n2:Context
rdf:value: For instance, in chondrogenesis, Wnt-4 signals through the β-catenin–TCF-LEF pathway to accelerate chondrogenesis (Hartmann and Tabin, >>2000<<), a process in which SOX9 function is essential (Bi et al., 1999; Akiyama et al., 2002).
n2:mentions: n3:10862751

Subject Item: _:vb780387
rdf:type: n2:Context
rdf:value: For instance, in chondrogenesis, Wnt-4 signals through the β-catenin–TCF-LEF pathway to accelerate chondrogenesis (Hartmann and Tabin, 2000), a process in which SOX9 function is essential (Bi et al., >>1999<<; Akiyama et al., 2002).
n2:mentions: n3:10319868

Subject Item: _:vb780388
rdf:type: n2:Context
rdf:value: For instance, in chondrogenesis, Wnt-4 signals through the β-catenin–TCF-LEF pathway to accelerate chondrogenesis (Hartmann and Tabin, 2000), a process in which SOX9 function is essential (Bi et al., 1999; Akiyama et al., >>2002<<). Moreover, in the developing mouse limb buds, the expression patterns of SOX9 and of the Wnt-antagonist Dickkopf are mutually exclusive (Grotewold and Ruther, 2002). Wnt signals are also involved in the development of the neural crests
n2:mentions: n3:12414734

Subject Item: _:vb780389
rdf:type: n2:Context
rdf:value: Moreover, in the developing mouse limb buds, the expression patterns of SOX9 and of the Wnt-antagonist Dickkopf are mutually exclusive (Grotewold and Ruther, >>2002<<). Wnt signals are also involved in the development of the neural crests (Yanfeng et al., 2003), where SOX9 has also recently been found to be required (Spokony et al., 2002; Cheung and Briscoe, 2003; Mori-Akiyama et al., 2003). It will be
n2:mentions: n3:12455632

Subject Item: _:vb780390
rdf:type: n2:Context
rdf:value: Wnt signals are also involved in the development of the neural crests (Yanfeng et al., >>2003<<), where SOX9 has also recently been found to be required (Spokony et al., 2002; Cheung and Briscoe, 2003; Mori-Akiyama et al., 2003).
n2:mentions: n3:12655639

Subject Item: _:vb780391
rdf:type: n2:Context
rdf:value: Wnt signals are also involved in the development of the neural crests (Yanfeng et al., 2003), where SOX9 has also recently been found to be required (Spokony et al., >>2002<<; Cheung and Briscoe, 2003; Mori-Akiyama et al., 2003).
n2:mentions: n3:11807034

Subject Item: _:vb780392
rdf:type: n2:Context
rdf:value: Wnt signals are also involved in the development of the neural crests (Yanfeng et al., 2003), where SOX9 has also recently been found to be required (Spokony et al., 2002; Cheung and Briscoe, >>2003<<; Mori-Akiyama et al., 2003).
n2:mentions: n3:14522876

Subject Item: _:vb780393
rdf:type: n2:Context
rdf:value: Wnt signals are also involved in the development of the neural crests (Yanfeng et al., 2003), where SOX9 has also recently been found to be required (Spokony et al., 2002; Cheung and Briscoe, 2003; Mori-Akiyama et al., >>2003<<). It will be interesting to determine whether Wnt signals are involved in the regulation of SOX9 in such structures.
n2:mentions: n3:12878728

Subject Item: _:vb780394
rdf:type: n2:Context
rdf:value: For instance, SOX9 represses the expression of the CDX2 transcription factor, known to be mostly active in villus cells (Silberg et al., >>2000<<; Rings et al., 2001) and to promote cell differentiation by activating transcription of genes encoding typical differentiation markers, including MUC2, sucrase-isomaltase, and lactase (Lorentz et al., 1997; Yamamoto et al., 2003).
n2:mentions: n3:11040183

Subject Item: _:vb780395
rdf:type: n2:Context
rdf:value: For instance, SOX9 represses the expression of the CDX2 transcription factor, known to be mostly active in villus cells (Silberg et al., 2000; Rings et al., >>2001<<) and to promote cell differentiation by activating transcription of genes encoding typical differentiation markers, including MUC2, sucrase-isomaltase, and lactase (Lorentz et al., 1997; Yamamoto et al., 2003).
n2:mentions: n3:11729123

Subject Item: _:vb780396
rdf:type: n2:Context
rdf:value: cells (Silberg et al., 2000; Rings et al., 2001) and to promote cell differentiation by activating transcription of genes encoding typical differentiation markers, including MUC2, sucrase-isomaltase, and lactase (Lorentz et al., >>1997<<; Yamamoto et al., 2003).
n2:mentions: n3:9396760

Subject Item: _:vb780397
rdf:type: n2:Context
rdf:value: al., 2000; Rings et al., 2001) and to promote cell differentiation by activating transcription of genes encoding typical differentiation markers, including MUC2, sucrase-isomaltase, and lactase (Lorentz et al., 1997; Yamamoto et al., >>2003<<). To date, SOX9 has generally been described as a transcriptional activator (Südbeck et al., 1996; Bell et al., 1997; Lefebvre et al., 1997; Ng et al., 1997; de Santa Barbara et al., 1998; Liu et al., 2000; Sekiya et al., 2000; Liu et al.
n2:mentions: n3:12559945

Subject Item: _:vb780398
rdf:type: n2:Context
rdf:value: To date, SOX9 has generally been described as a transcriptional activator (Südbeck et al., >>1996<<; Bell et al., 1997; Lefebvre et al., 1997; Ng et al., 1997; de Santa Barbara et al., 1998; Liu et al., 2000; Sekiya et al., 2000; Liu et al., 2001; Panda et al., 2001), although it was recently found to mediate a dual transcriptional
n2:mentions: n3:8640233

Subject Item: _:vb780399
rdf:type: n2:Context
rdf:value: To date, SOX9 has generally been described as a transcriptional activator (Südbeck et al., 1996; Bell et al., >>1997<<; Lefebvre et al., 1997; Ng et al., 1997; de Santa Barbara et al., 1998; Liu et al., 2000; Sekiya et al., 2000; Liu et al., 2001; Panda et al., 2001), although it was recently found to mediate a dual transcriptional effect on the COL2A1
n2:mentions: n3:9171829

Subject Item: _:vb780400
rdf:type: n2:Context
rdf:value: To date, SOX9 has generally been described as a transcriptional activator (Südbeck et al., 1996; Bell et al., 1997; Lefebvre et al., >>1997<<; Ng et al., 1997; de Santa Barbara et al., 1998; Liu et al., 2000; Sekiya et al., 2000; Liu et al., 2001; Panda et al., 2001), although it was recently found to mediate a dual transcriptional effect on the COL2A1 gene, depending on the
n2:mentions: n3:9121483

Subject Item: _:vb780401
rdf:type: n2:Context
rdf:value: To date, SOX9 has generally been described as a transcriptional activator (Südbeck et al., 1996; Bell et al., 1997; Lefebvre et al., 1997; Ng et al., >>1997<<; de Santa Barbara et al., 1998; Liu et al., 2000; Sekiya et al., 2000; Liu et al., 2001; Panda et al., 2001), although it was recently found to mediate a dual transcriptional effect on the COL2A1 gene, depending on the promoter elements
n2:mentions: n3:9119111

Subject Item: _:vb780402
rdf:type: n2:Context
rdf:value: To date, SOX9 has generally been described as a transcriptional activator (Südbeck et al., 1996; Bell et al., 1997; Lefebvre et al., 1997; Ng et al., 1997; de Santa Barbara et al., >>1998<<; Liu et al., 2000; Sekiya et al., 2000; Liu et al., 2001; Panda et al., 2001), although it was recently found to mediate a dual transcriptional effect on the COL2A1 gene, depending on the promoter elements involved (Kypriotou et al.,
n2:mentions: n3:9774680

Subject Item: _:vb780403
rdf:type: n2:Context
rdf:value: To date, SOX9 has generally been described as a transcriptional activator (Südbeck et al., 1996; Bell et al., 1997; Lefebvre et al., 1997; Ng et al., 1997; de Santa Barbara et al., 1998; Liu et al., >>2000<<; Sekiya et al., 2000; Liu et al., 2001; Panda et al., 2001), although it was recently found to mediate a dual transcriptional effect on the COL2A1 gene, depending on the promoter elements involved (Kypriotou et al., 2003).
n2:mentions: n3:10777565

Subject Item: _:vb780404
rdf:type: n2:Context
rdf:value: To date, SOX9 has generally been described as a transcriptional activator (Südbeck et al., 1996; Bell et al., 1997; Lefebvre et al., 1997; Ng et al., 1997; de Santa Barbara et al., 1998; Liu et al., 2000; Sekiya et al., >>2000<<; Liu et al., 2001; Panda et al., 2001), although it was recently found to mediate a dual transcriptional effect on the COL2A1 gene, depending on the promoter elements involved (Kypriotou et al., 2003).
n2:mentions: n3:10753864

Subject Item: _:vb780405
rdf:type: n2:Context
rdf:value: date, SOX9 has generally been described as a transcriptional activator (Südbeck et al., 1996; Bell et al., 1997; Lefebvre et al., 1997; Ng et al., 1997; de Santa Barbara et al., 1998; Liu et al., 2000; Sekiya et al., 2000; Liu et al., >>2001<<; Panda et al., 2001), although it was recently found to mediate a dual transcriptional effect on the COL2A1 gene, depending on the promoter elements involved (Kypriotou et al., 2003).
n2:mentions: n3:11517178

Subject Item: _:vb780406
rdf:type: n2:Context
rdf:value: been described as a transcriptional activator (Südbeck et al., 1996; Bell et al., 1997; Lefebvre et al., 1997; Ng et al., 1997; de Santa Barbara et al., 1998; Liu et al., 2000; Sekiya et al., 2000; Liu et al., 2001; Panda et al., >>2001<<), although it was recently found to mediate a dual transcriptional effect on the COL2A1 gene, depending on the promoter elements involved (Kypriotou et al., 2003).
n2:mentions: n3:11514554

Subject Item: _:vb780407
rdf:type: n2:Context
rdf:value: Liu et al., 2000; Sekiya et al., 2000; Liu et al., 2001; Panda et al., 2001), although it was recently found to mediate a dual transcriptional effect on the COL2A1 gene, depending on the promoter elements involved (Kypriotou et al., >>2003<<). Interestingly, recent studies in the central nervous system showed that SOX1, SOX2, and SOX3 act as repressors of postmitotic neuronal markers.
n2:mentions: n3:12713737

Subject Item: _:vb780408
rdf:type: n2:Context
rdf:value: In this case, SOX1–3 inhibit neurogenesis by activating transcription and, conversely, repression of their as yet unknown target genes facilitates neuronal differentiation (Bylund et al., >>2003<<). Here, we show that a forced activator version of SOX9 (SOX9-VP16) mimics the properties of wild-type SOX9, which suggests an analogous situation, where the intermediate activation of a repressor transcription factor mediates the
n2:mentions: n3:14517545

Subject Item: _:vb780409
rdf:type: n2:Context
rdf:value: Because one reported role of the Wnt pathway is the maintenance of an undifferentiated cell phenotype (van de Wetering et al., >>2002<<), our results suggest that SOX9 might be involved in mediating part of this function.
n2:mentions: n3:12408868

Subject Item: _:vb780410
rdf:type: n2:Context
rdf:value: Furthermore, SOX10, closely related to SOX9, is involved in the maintenance of neural crest stem cells multipotency and inhibition of neural differentiation (Kim et al., >>2003<<), SOX2 maintains precursor cells of the mouse blastocyst in a multipotent state (Avilion et al., 2003), and SOX1–3 counteract the activity of proneural proteins to keep neural cells undifferentiated (Bylund et al., 2003).
n2:mentions: n3:12691661

Subject Item: _:vb780411
rdf:type: n2:Context
rdf:value: SOX9, is involved in the maintenance of neural crest stem cells multipotency and inhibition of neural differentiation (Kim et al., 2003), SOX2 maintains precursor cells of the mouse blastocyst in a multipotent state (Avilion et al., >>2003<<), and SOX1–3 counteract the activity of proneural proteins to keep neural cells undifferentiated (Bylund et al., 2003).
n2:mentions: n3:12514105

Subject Item: _:vb780412
rdf:type: n2:Context
rdf:value: (Kim et al., 2003), SOX2 maintains precursor cells of the mouse blastocyst in a multipotent state (Avilion et al., 2003), and SOX1–3 counteract the activity of proneural proteins to keep neural cells undifferentiated (Bylund et al., >>2003<<). Thus, contribution to the maintenance of cells in an undifferentiated state might be a property shared by several SOX transcription factors, and our finding that SOX9 is regulated by the Wnt pathway, which is also known to inhibit
n2:mentions: n3:14517545

Subject Item: _:vb780413
rdf:type: n2:Context
rdf:value: We found that SOX9 negatively regulates the CDX2 tumor suppressor gene, which is frequently very weakly expressed in colon cancers (Ee et al., >>1995<<; Mallo et al., 1997), especially in poorly differentiated lesions (Hinoi et al., 2001).
n2:mentions: n3:7677172

Subject Item: _:vb780414
rdf:type: n2:Context
rdf:value: We found that SOX9 negatively regulates the CDX2 tumor suppressor gene, which is frequently very weakly expressed in colon cancers (Ee et al., 1995; Mallo et al., >>1997<<), especially in poorly differentiated lesions (Hinoi et al., 2001).
n2:mentions: n3:9036867

Subject Item: _:vb780415
rdf:type: n2:Context
rdf:value: We found that SOX9 negatively regulates the CDX2 tumor suppressor gene, which is frequently very weakly expressed in colon cancers (Ee et al., 1995; Mallo et al., 1997), especially in poorly differentiated lesions (Hinoi et al., >>2001<<). Mice heterozygous for the CDX2 gene are hypersensitive to sporadic, chemically induced, colon carcinogenesis (Bonhomme et al., 2003), and this was confirmed in a mouse model of familial adenomatous polyposis (Aoki et al., 2003).
n2:mentions: n3:11733373

Subject Item: _:vb780416
rdf:type: n2:Context
rdf:value: Mice heterozygous for the CDX2 gene are hypersensitive to sporadic, chemically induced, colon carcinogenesis (Bonhomme et al., >>2003<<), and this was confirmed in a mouse model of familial adenomatous polyposis (Aoki et al., 2003).
n2:mentions: n3:12970140

Subject Item: _:vb780417
rdf:type: n2:Context
rdf:value: Mice heterozygous for the CDX2 gene are hypersensitive to sporadic, chemically induced, colon carcinogenesis (Bonhomme et al., 2003), and this was confirmed in a mouse model of familial adenomatous polyposis (Aoki et al., >>2003<<). MUC2 deficiency also leads to spontaneous intestinal tumors (Velcich et al., 2002). Conversely, restoration of CDX2 expression in human colon carcinoma cells suppressed proliferation and soft agar growth (Hinoi et al., 2003). Here, we
n2:mentions: n3:14625550

Subject Item: _:vb780418
rdf:type: n2:Context
rdf:value: MUC2 deficiency also leads to spontaneous intestinal tumors (Velcich et al., >>2002<<). Conversely, restoration of CDX2 expression in human colon carcinoma cells suppressed proliferation and soft agar growth (Hinoi et al., 2003). Here, we find that overexpressing a dominant-negative version of SOX9 results in increased
n2:mentions: n3:11872843

Subject Item: _:vb780419
rdf:type: n2:Context
rdf:value: Conversely, restoration of CDX2 expression in human colon carcinoma cells suppressed proliferation and soft agar growth (Hinoi et al., >>2003<<). Here, we find that overexpressing a dominant-negative version of SOX9 results in increased CDX2 expression in cultured colon carcinoma cells. This suggests that strong SOX9 expression in tumors which contain a constitutive activation of
n2:mentions: n3:12947088

Subject Item: _:vb291653152
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 28
n2:hasRelevantPaperId: n3:17698607

Subject Item: _:vb291653153
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 20
n2:hasRelevantPaperId: n3:17934449

Subject Item: _:vb291653154
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 14
n2:hasRelevantPaperId: n3:19019766

Subject Item: _:vb291653155
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 13
n2:hasRelevantPaperId: n3:19228882

Subject Item: _:vb291653156
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 12
n2:hasRelevantPaperId: n3:17681175

Subject Item: _:vb291653157
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 12
n2:hasRelevantPaperId: n3:16085486

Subject Item: _:vb291653158
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 11
n2:hasRelevantPaperId: n3:21113151

Subject Item: _:vb291653159
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 11
n2:hasRelevantPaperId: n3:19329995

Subject Item: _:vb291653160
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 11
n2:hasRelevantPaperId: n3:9697701

Subject Item: _:vb291653161
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 11
n2:hasRelevantPaperId: n3:22246670

Subject Item: _:vb291653162
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 10
n2:hasRelevantPaperId: n3:9065402

Subject Item: _:vb291653163
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 10
n2:hasRelevantPaperId: n3:21113154

Subject Item: _:vb291653164
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 10
n2:hasRelevantPaperId: n3:15781631

Subject Item: _:vb291653165
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 10
n2:hasRelevantPaperId: n3:12865297

Subject Item: _:vb291653166
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 10
n2:hasRelevantPaperId: n3:12408868

Subject Item: _:vb291653167
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 9
n2:hasRelevantPaperId: n3:12408869

Subject Item: _:vb291653168
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 9
n2:hasRelevantPaperId: n3:17267606

Subject Item: _:vb291653169
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 9
n2:hasRelevantPaperId: n3:17785439

Subject Item: _:vb291653170
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 9
n2:hasRelevantPaperId: n3:9727977

Subject Item: _:vb291653171
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 9
n2:hasRelevantPaperId: n3:22810696

Subject Item: _:vb291653172
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 9
n2:hasRelevantPaperId: n3:15132997

Subject Item: _:vb291653173
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 9
n2:hasRelevantPaperId: n3:19269367

Subject Item: _:vb291653174
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 8
n2:hasRelevantPaperId: n3:9065401

Subject Item: _:vb291653175
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 8
n2:hasRelevantPaperId: n3:19092804

Subject Item: _:vb291653176
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 8
n2:hasRelevantPaperId: n3:15778706

Subject Item: _:vb291653177
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 8
n2:hasRelevantPaperId: n3:19047045

Subject Item: _:vb291653178
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 8
n2:hasRelevantPaperId: n3:22682243

Subject Item: _:vb291653179
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 7
n2:hasRelevantPaperId: n3:26095047

Subject Item: _:vb291653180
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 7
n2:hasRelevantPaperId: n3:7990924

Subject Item: _:vb291653181
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 7
n2:hasRelevantPaperId: n3:11739954

Subject Item: _:vb291653182
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 7
n2:hasRelevantPaperId: n3:18339840

Subject Item: _:vb291653183
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 7
n2:hasRelevantPaperId: n3:15282745

Subject Item: _:vb291653184
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 7
n2:hasRelevantPaperId: n3:23201164

Subject Item: _:vb291653185
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 7
n2:hasRelevantPaperId: n3:15077158

Subject Item: _:vb291653186
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 6
n2:hasRelevantPaperId: n3:15959515

Subject Item: _:vb291653187
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 6
n2:hasRelevantPaperId: n3:22922422

Subject Item: _:vb291653188
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 6
n2:hasRelevantPaperId: n3:27043282

Subject Item: _:vb291653189
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 6
n2:hasRelevantPaperId: n3:17625949

Subject Item: _:vb291653190
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 6
n2:hasRelevantPaperId: n3:8001137

Subject Item: _:vb291653191
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 6
n2:hasRelevantPaperId: n3:17081971

Subject Item: _:vb291653192
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 6
n2:hasRelevantPaperId: n3:20018966

Subject Item: _:vb291653193
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 6
n2:hasRelevantPaperId: n3:20103652

Subject Item: _:vb291653194
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 6
n2:hasRelevantPaperId: n3:19619488

Subject Item: _:vb291653195
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 6
n2:hasRelevantPaperId: n3:15017003

Subject Item: _:vb291653196
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 5
n2:hasRelevantPaperId: n3:18432252

Subject Item: _:vb291653197
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 5
n2:hasRelevantPaperId: n3:16199517

Subject Item: _:vb291653198
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 5
n2:hasRelevantPaperId: n3:21090969

Subject Item: _:vb291653199
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 5
n2:hasRelevantPaperId: n3:27429045

Subject Item: _:vb291653200
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 5
n2:hasRelevantPaperId: n3:16083717

Subject Item: _:vb291653201
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 5
n2:hasRelevantPaperId: n3:25865482

Subject Item: _:vb291653202
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 5
n2:hasRelevantPaperId: n3:27569216

Subject Item: _:vb291653203
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 5
n2:hasRelevantPaperId: n3:22385965

Subject Item: _:vb291653204
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 5
n2:hasRelevantPaperId: n3:11846609

Subject Item: _:vb291653205
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 5
n2:hasRelevantPaperId: n3:21512138

Subject Item: _:vb291653206
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 5
n2:hasRelevantPaperId: n3:18519685

Subject Item: _:vb291653207
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 5
n2:hasRelevantPaperId: n3:11809809

Subject Item: _:vb291653208
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 5
n2:hasRelevantPaperId: n3:25685828

Subject Item: _:vb291653209
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 5
n2:hasRelevantPaperId: n3:20185687

Subject Item: _:vb291653210
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 5
n2:hasRelevantPaperId: n3:18808327

Subject Item: _:vb291653211
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 5
n2:hasRelevantPaperId: n3:20871603

Subject Item: _:vb291653212
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 5
n2:hasRelevantPaperId: n3:21238454

Subject Item: _:vb291653213
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 5
n2:hasRelevantPaperId: n3:17234760

Subject Item: _:vb291653214
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 5
n2:hasRelevantPaperId: n3:15378062

Subject Item: _:vb291653215
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 5
n2:hasRelevantPaperId: n3:26170137

Subject Item: _:vb291653216
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 5
n2:hasRelevantPaperId: n3:21861142

Subject Item: _:vb291653217
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 4
n2:hasRelevantPaperId: n3:17377531

Subject Item: _:vb291653218
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 4
n2:hasRelevantPaperId: n3:26040697

Subject Item: _:vb291653219
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 4
n2:hasRelevantPaperId: n3:19549527

Subject Item: _:vb291653220
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 4
n2:hasRelevantPaperId: n3:11040183

Subject Item: _:vb291653221
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 4
n2:hasRelevantPaperId: n3:28575679

Subject Item: _:vb291653222
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 4
n2:hasRelevantPaperId: n3:17320548

Subject Item: _:vb291653223
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 4
n2:hasRelevantPaperId: n3:18794802

Subject Item: _:vb291653224
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 4
n2:hasRelevantPaperId: n3:22190634

Subject Item: _:vb291653225
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 4
n2:hasRelevantPaperId: n3:15959516

Subject Item: _:vb291653226
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 4
n2:hasRelevantPaperId: n3:23290134

Subject Item: _:vb291653227
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 4
n2:hasRelevantPaperId: n3:15829953

Subject Item: _:vb291653228
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 4
n2:hasRelevantPaperId: n3:18087279

Subject Item: _:vb291653229
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 4
n2:hasRelevantPaperId: n3:27248473

Subject Item: _:vb291653230
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 4
n2:hasRelevantPaperId: n3:2100251

Subject Item: _:vb291653231
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 4
n2:hasRelevantPaperId: n3:23306204

Subject Item: _:vb291653232
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 4
n2:hasRelevantPaperId: n3:24532713

Subject Item: _:vb291653233
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 4
n2:hasRelevantPaperId: n3:16109882

Subject Item: _:vb291653234
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 4
n2:hasRelevantPaperId: n3:28988015

Subject Item: _:vb291653235
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 4
n2:hasRelevantPaperId: n3:9916792

Subject Item: _:vb291653236
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 4
n2:hasRelevantPaperId: n3:11807034

Subject Item: _:vb291653237
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 4
n2:hasRelevantPaperId: n3:23660500

Subject Item: _:vb291653238
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 4
n2:hasRelevantPaperId: n3:18798982

Subject Item: _:vb291653239
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 4
n2:hasRelevantPaperId: n3:30207593

Subject Item: _:vb291653240
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 4
n2:hasRelevantPaperId: n3:18626943

Subject Item: _:vb291653241
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 4
n2:hasRelevantPaperId: n3:12842915

Subject Item: _:vb291653242
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 4
n2:hasRelevantPaperId: n3:17570220

Subject Item: _:vb291653243
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 4
n2:hasRelevantPaperId: n3:9311916

Subject Item: _:vb291653244
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 4
n2:hasRelevantPaperId: n3:15342386

Subject Item: _:vb291653245
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 4
n2:hasRelevantPaperId: n3:20651055

Subject Item: _:vb291653246
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 4
n2:hasRelevantPaperId: n3:21727895

Subject Item: _:vb291653247
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 4
n2:hasRelevantPaperId: n3:7937951

Subject Item: _:vb291653248
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 4
n2:hasRelevantPaperId: n3:22361729

Subject Item: _:vb291653249
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 4
n2:hasRelevantPaperId: n3:18557758

Subject Item: _:vb291653250
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 4
n2:hasRelevantPaperId: n3:22393260

Subject Item: _:vb291653251
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 4
n2:hasRelevantPaperId: n3:23273993

Subject Item: _:vb291653252
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 4
n2:hasRelevantPaperId: n3:18325490

Subject Item: _:vb291653253
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 4
n2:hasRelevantPaperId: n3:11057903

Subject Item: _:vb291653254
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 4
n2:hasRelevantPaperId: n3:23426182

Subject Item: _:vb291653255
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 4
n2:hasRelevantPaperId: n3:26036262

Subject Item: _:vb291653256
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 4
n2:hasRelevantPaperId: n3:26980019

Subject Item: _:vb291653257
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 4
n2:hasRelevantPaperId: n3:18593557

Subject Item: _:vb291653258
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 4
n2:hasRelevantPaperId: n3:19543319

Subject Item: _:vb291653259
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 4
n2:hasRelevantPaperId: n3:10921899

Subject Item: _:vb291653260
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 3
n2:hasRelevantPaperId: n3:16510874

Subject Item: _:vb291653261
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 3
n2:hasRelevantPaperId: n3:29144463

Subject Item: _:vb291653262
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 3
n2:hasRelevantPaperId: n3:19567251

Subject Item: _:vb291653263
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 3
n2:hasRelevantPaperId: n3:2188735

Subject Item: _:vb291653264
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 3
n2:hasRelevantPaperId: n3:12051735

Subject Item: _:vb291653265
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 3
n2:hasRelevantPaperId: n3:23989955

Subject Item: _:vb291653266
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 3
n2:hasRelevantPaperId: n3:19879217

Subject Item: _:vb291653267
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 3
n2:hasRelevantPaperId: n3:22586121

Subject Item: _:vb291653268
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 3
n2:hasRelevantPaperId: n3:23870119

Subject Item: _:vb291653269
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 3
n2:hasRelevantPaperId: n3:24906622

Subject Item: _:vb291653270
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 3
n2:hasRelevantPaperId: n3:25220842

Subject Item: _:vb291653271
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 3
n2:hasRelevantPaperId: n3:19324043

Subject Item: _:vb291653272
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 3
n2:hasRelevantPaperId: n3:12629218

Subject Item: _:vb291653273
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 3
n2:hasRelevantPaperId: n3:26009899

Subject Item: _:vb291653274
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 3
n2:hasRelevantPaperId: n3:22385677

Subject Item: _:vb291653275
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 3
n2:hasRelevantPaperId: n3:28347989

Subject Item: _:vb291653276
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 3
n2:hasRelevantPaperId: n3:19631281

Subject Item: _:vb291653277
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 3
n2:hasRelevantPaperId: n3:20417836

Subject Item: _:vb291653278
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 3
n2:hasRelevantPaperId: n3:24308963

Subject Item: _:vb291653279
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 3
n2:hasRelevantPaperId: n3:1651562

Subject Item: _:vb291653280
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 3
n2:hasRelevantPaperId: n3:21321311

Subject Item: _:vb291653281
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 3
n2:hasRelevantPaperId: n3:16230531

Subject Item: _:vb291653282
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 3
n2:hasRelevantPaperId: n3:18333897

Subject Item: _:vb291653283
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 3
n2:hasRelevantPaperId: n3:1458460

Subject Item: _:vb291653284
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 3
n2:hasRelevantPaperId: n3:10027409

Subject Item: _:vb291653285
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 3
n2:hasRelevantPaperId: n3:15590741

Subject Item: _:vb291653286
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 3
n2:hasRelevantPaperId: n3:1350108

Subject Item: _:vb291653287
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 3
n2:hasRelevantPaperId: n3:29499500

Subject Item: _:vb291653288
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 3
n2:hasRelevantPaperId: n3:18794900

Subject Item: _:vb291653289
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 3
n2:hasRelevantPaperId: n3:20418870

Subject Item: _:vb291653290
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 3
n2:hasRelevantPaperId: n3:22895187

Subject Item: _:vb291653291
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 3
n2:hasRelevantPaperId: n3:23258168

Subject Item: _:vb291653292
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 3
n2:hasRelevantPaperId: n3:9233789

Subject Item: _:vb291653293
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 3
n2:hasRelevantPaperId: n3:22388892

Subject Item: _:vb291653294
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 3
n2:hasRelevantPaperId: n3:12839979

Subject Item: _:vb291653295
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 3
n2:hasRelevantPaperId: n3:21376230

Subject Item: _:vb291653296
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 3
n2:hasRelevantPaperId: n3:16464855

Subject Item: _:vb291653297
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 3
n2:hasRelevantPaperId: n3:15034581

Subject Item: _:vb291653298
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 3
n2:hasRelevantPaperId: n3:18062147

Subject Item: _:vb291653299
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 3
n2:hasRelevantPaperId: n3:11326276

Subject Item: _:vb291653300
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 3
n2:hasRelevantPaperId: n3:24086078

Subject Item: _:vb291653301
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 3
n2:hasRelevantPaperId: n3:17702866

Subject Item: _:vb291653302
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 3
n2:hasRelevantPaperId: n3:17881565

Subject Item: _:vb291653303
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 3
n2:hasRelevantPaperId: n3:4440635

Subject Item: _:vb291653304
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 3
n2:hasRelevantPaperId: n3:21297661

Subject Item: _:vb291653305
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 3
n2:hasRelevantPaperId: n3:15096597

Subject Item: _:vb291653306
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 3
n2:hasRelevantPaperId: n3:24550486

Subject Item: _:vb291653307
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 3
n2:hasRelevantPaperId: n3:10545105

Subject Item: _:vb291653308
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 3
n2:hasRelevantPaperId: n3:22488688

Subject Item: _:vb291653309
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 3
n2:hasRelevantPaperId: n3:20599897

Subject Item: _:vb291653310
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 3
n2:hasRelevantPaperId: n3:11857796

Subject Item: _:vb291653311
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 3
n2:hasRelevantPaperId: n3:23592398

Subject Item: _:vb291653312
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 3
n2:hasRelevantPaperId: n3:15473857

Subject Item: _:vb291653313
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 3
n2:hasRelevantPaperId: n3:16809766

Subject Item: _:vb291653314
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 3
n2:hasRelevantPaperId: n3:18628392

Subject Item: _:vb291653315
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 3
n2:hasRelevantPaperId: n3:19786015

Subject Item: _:vb291653316
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 3
n2:hasRelevantPaperId: n3:8640233

Subject Item: _:vb291653317
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 3
n2:hasRelevantPaperId: n3:21383077

Subject Item: _:vb291653318
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 3
n2:hasRelevantPaperId: n3:23727861

Subject Item: _:vb291653319
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 3
n2:hasRelevantPaperId: n3:20569694

Subject Item: _:vb291653320
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 3
n2:hasRelevantPaperId: n3:21237710

Subject Item: _:vb291653321
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 3
n2:hasRelevantPaperId: n3:24480852

Subject Item: _:vb291653322
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 3
n2:hasRelevantPaperId: n3:24089213

Subject Item: _:vb291653323
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 3
n2:hasRelevantPaperId: n3:15473860

Subject Item: _:vb291653324
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 3
n2:hasRelevantPaperId: n3:15979579

Subject Item: _:vb291653325
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 3
n2:hasRelevantPaperId: n3:30429586

Subject Item: _:vb291653326
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 3
n2:hasRelevantPaperId: n3:10392709

Subject Item: _:vb291653327
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 3
n2:hasRelevantPaperId: n3:10514384

Subject Item: _:vb291653328
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 3
n2:hasRelevantPaperId: n3:15289330

Subject Item: _:vb291653329
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 3
n2:hasRelevantPaperId: n3:18400942

Subject Item: _:vb291653330
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 3
n2:hasRelevantPaperId: n3:8552090

Subject Item: _:vb291653331
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 3
n2:hasRelevantPaperId: n3:12015290

Subject Item: _:vb291653332
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 3
n2:hasRelevantPaperId: n3:16619050

Subject Item: _:vb291653333
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 3
n2:hasRelevantPaperId: n3:14522876

Subject Item: _:vb291653334
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 3
n2:hasRelevantPaperId: n3:21915337

Subject Item: _:vb291653335
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 3
n2:hasRelevantPaperId: n3:23635786

Subject Item: _:vb291653336
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 3
n2:hasRelevantPaperId: n3:15378020

Subject Item: _:vb291653337
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 3
n2:hasRelevantPaperId: n3:24904831

Subject Item: _:vb291653338
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 3
n2:hasRelevantPaperId: n3:21419747

Subject Item: _:vb291653339
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 3
n2:hasRelevantPaperId: n3:24191021

Subject Item: _:vb291653340
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 3
n2:hasRelevantPaperId: n3:27880941

Subject Item: _:vb291653341
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 3
n2:hasRelevantPaperId: n3:10489374

Subject Item: _:vb291653342
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 3
n2:hasRelevantPaperId: n3:21978911

Subject Item: _:vb291653343
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 3
n2:hasRelevantPaperId: n3:11872843

Subject Item: _:vb291653344
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 3
n2:hasRelevantPaperId: n3:18371393

Subject Item: _:vb291653345
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 3
n2:hasRelevantPaperId: n3:18537122

Subject Item: _:vb291653346
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 3
n2:hasRelevantPaperId: n3:21205878

Subject Item: _:vb291653347
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 3
n2:hasRelevantPaperId: n3:10201372

Subject Item: _:vb291653348
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 3
n2:hasRelevantPaperId: n3:15198980

Subject Item: _:vb291653349
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 3
n2:hasRelevantPaperId: n3:9990071

Subject Item: _:vb291653350
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 3
n2:hasRelevantPaperId: n3:11955436

Subject Item: _:vb291653351
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 3
n2:hasRelevantPaperId: n3:24058167

Subject Item: _:vb291653352
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:24976009

Subject Item: _:vb291653353
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:15956967

Subject Item: _:vb291653354
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:17290008

Subject Item: _:vb291653355
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:17474097

Subject Item: _:vb291653356
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:28118628

Subject Item: _:vb291653357
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:19059247

Subject Item: _:vb291653358
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:19272386

Subject Item: _:vb291653359
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:30625324

Subject Item: _:vb291653360
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:19487818

Subject Item: _:vb291653361
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:19655378

Subject Item: _:vb291653362
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:8787755

Subject Item: _:vb291653363
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:10597251

Subject Item: _:vb291653364
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:22438566

Subject Item: _:vb291653365
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:11752446

Subject Item: _:vb291653366
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:12619811

Subject Item: _:vb291653367
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:23398152

Subject Item: _:vb291653368
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:27771362

Subject Item: _:vb291653369
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:17897439

Subject Item: _:vb291653370
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:29204504

Subject Item: _:vb291653371
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:30259138

Subject Item: _:vb291653372
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:19509063

Subject Item: _:vb291653373
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:22166544

Subject Item: _:vb291653374
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:22766303

Subject Item: _:vb291653375
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:23736260

Subject Item: _:vb291653376
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:15716339

Subject Item: _:vb291653377
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:27079975

Subject Item: _:vb291653378
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:27413168

Subject Item: _:vb291653379
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:17545618

Subject Item: _:vb291653380
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:28345602

Subject Item: _:vb291653381
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:18794798

Subject Item: _:vb291653382
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:19822006

Subject Item: _:vb291653383
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:20122401

Subject Item: _:vb291653384
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:21351269

Subject Item: _:vb291653385
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:10802651

Subject Item: _:vb291653386
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:10934025

Subject Item: _:vb291653387
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:11306497

Subject Item: _:vb291653388
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:22190486

Subject Item: _:vb291653389
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:24060864

Subject Item: _:vb291653390
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:24302456

Subject Item: _:vb291653391
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:15314234

Subject Item: _:vb291653392
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:15652704

Subject Item: _:vb291653393
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:24821987

Subject Item: _:vb291653394
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:24981363

Subject Item: _:vb291653395
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:16258171

Subject Item: _:vb291653396
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:26526724

Subject Item: _:vb291653397
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:17202265

Subject Item: _:vb291653398
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:19273910

Subject Item: _:vb291653399
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:20301211

Subject Item: _:vb291653400
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:10733525

Subject Item: _:vb291653401
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:12943221

Subject Item: _:vb291653402
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:23835194

Subject Item: _:vb291653403
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:17142326

Subject Item: _:vb291653404
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:18296708

Subject Item: _:vb291653405
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:18373705

Subject Item: _:vb291653406
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:19015024

Subject Item: _:vb291653407
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:30268439

Subject Item: _:vb291653408
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:19234110

Subject Item: _:vb291653409
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:19589945

Subject Item: _:vb291653410
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:20080688

Subject Item: _:vb291653411
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:20383121

Subject Item: _:vb291653412
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:9212098

Subject Item: _:vb291653413
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:20937839

Subject Item: _:vb291653414
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:10521349

Subject Item: _:vb291653415
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:11689955

Subject Item: _:vb291653416
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:13353477

Subject Item: _:vb291653417
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:15520178

Subject Item: _:vb291653418
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:24909886

Subject Item: _:vb291653419
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:19029987

Subject Item: _:vb291653420
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:20975679

Subject Item: _:vb291653421
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:21527727

Subject Item: _:vb291653422
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:11306549

Subject Item: _:vb291653423
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:11553815

Subject Item: _:vb291653424
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:12093753

Subject Item: _:vb291653425
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:12189386

Subject Item: _:vb291653426
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:23362343

Subject Item: _:vb291653427
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:24825347

Subject Item: _:vb291653428
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:25260709

Subject Item: _:vb291653429
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:16538672

Subject Item: _:vb291653430
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:17030180

Subject Item: _:vb291653431
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:26855967

Subject Item: _:vb291653432
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:18351289

Subject Item: _:vb291653433
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:21983963

Subject Item: _:vb291653434
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:11201432

Subject Item: _:vb291653435
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:11756228

Subject Item: _:vb291653436
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:22674330

Subject Item: _:vb291653437
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:15000148

Subject Item: _:vb291653438
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:24332836

Subject Item: _:vb291653439
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:15998806

Subject Item: _:vb291653440
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:16107537

Subject Item: _:vb291653441
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:26013289

Subject Item: _:vb291653442
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:26457759

Subject Item: _:vb291653443
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:17724330

Subject Item: _:vb291653444
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:28187288

Subject Item: _:vb291653445
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:30270040

Subject Item: _:vb291653446
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:19379690

Subject Item: _:vb291653447
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:21393571

Subject Item: _:vb291653448
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:21600206

Subject Item: _:vb291653449
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:10769246

Subject Item: _:vb291653450
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:21831298

Subject Item: _:vb291653451
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:10883398

Subject Item: _:vb291653452
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:21999944

Subject Item: _:vb291653453
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:11691783

Subject Item: _:vb291653454
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:11792709

Subject Item: _:vb291653455
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:22692129

Subject Item: _:vb291653456
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:23040474

Subject Item: _:vb291653457
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:23349860

Subject Item: _:vb291653458
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:13372265

Subject Item: _:vb291653459
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:14749129

Subject Item: _:vb291653460
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:23877564

Subject Item: _:vb291653461
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:17563382

Subject Item: _:vb291653462
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:27617575

Subject Item: _:vb291653463
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:28059064

Subject Item: _:vb291653464
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:18414679

Subject Item: _:vb291653465
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:18794899

Subject Item: _:vb291653466
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:19130170

Subject Item: _:vb291653467
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:9295317

Subject Item: _:vb291653468
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:12094235

Subject Item: _:vb291653469
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:15961883

Subject Item: _:vb291653470
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:17030556

Subject Item: _:vb291653471
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:28279198

Subject Item: _:vb291653472
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:18445819

Subject Item: _:vb291653473
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:29155957

Subject Item: _:vb291653474
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:1651563

Subject Item: _:vb291653475
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:4440632

Subject Item: _:vb291653476
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:7666392

Subject Item: _:vb291653477
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:20887898

Subject Item: _:vb291653478
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:21374063

Subject Item: _:vb291653479
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:11595728

Subject Item: _:vb291653480
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:15361487

Subject Item: _:vb291653481
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:16107730

Subject Item: _:vb291653482
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:16395311

Subject Item: _:vb291653483
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:17143293

Subject Item: _:vb291653484
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:17237784

Subject Item: _:vb291653485
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:27571710

Subject Item: _:vb291653486
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:28984791

Subject Item: _:vb291653487
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:30118745

Subject Item: _:vb291653488
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:20085740

Subject Item: _:vb291653489
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:9393971

Subject Item: _:vb291653490
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:21217637

Subject Item: _:vb291653491
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:22770212

Subject Item: _:vb291653492
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:12239569

Subject Item: _:vb291653493
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:24157873

Subject Item: _:vb291653494
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:17681174

Subject Item: _:vb291653495
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:28358093

Subject Item: _:vb291653496
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:18418383

Subject Item: _:vb291653497
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:8592733

Subject Item: _:vb291653498
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:20513432

Subject Item: _:vb291653499
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:22044670

Subject Item: _:vb291653500
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:12194848

Subject Item: _:vb291653501
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:16647036

Subject Item: _:vb291653502
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:26863187

Subject Item: _:vb291653503
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:18353764

Subject Item: _:vb291653504
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:18451032

Subject Item: _:vb291653505
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:30927915

Subject Item: _:vb291653506
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:23840480

Subject Item: _:vb291653507
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:15084848

Subject Item: _:vb291653508
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:24220295

Subject Item: _:vb291653509
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:24888586

Subject Item: _:vb291653510
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:25308311

Subject Item: _:vb291653511
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:16954380

Subject Item: _:vb291653512
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:17237808

Subject Item: _:vb291653513
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:18385740

Subject Item: _:vb291653514
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:8655584

Subject Item: _:vb291653515
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:9774680

Subject Item: _:vb291653516
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:21225631

Subject Item: _:vb291653517
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:10898789

Subject Item: _:vb291653518
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:23142137

Subject Item: _:vb291653519
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:23352663

Subject Item: _:vb291653520
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:13663040

Subject Item: _:vb291653521
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:24952462

Subject Item: _:vb291653522
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:25099011

Subject Item: _:vb291653523
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:27105493

Subject Item: _:vb291653524
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:18055444

Subject Item: _:vb291653525
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:29108672

Subject Item: _:vb291653526
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:30811997

Subject Item: _:vb291653527
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:19450512

Subject Item: _:vb291653528
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:1459863

Subject Item: _:vb291653529
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:19924227

Subject Item: _:vb291653530
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:10037800

Subject Item: _:vb291653531
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:10579974

Subject Item: _:vb291653532
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:22644962

Subject Item: _:vb291653533
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:15469841

Subject Item: _:vb291653534
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:15665104

Subject Item: _:vb291653535
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:16554309

Subject Item: _:vb291653536
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:26109046

Subject Item: _:vb291653537
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:18268006

Subject Item: _:vb291653538
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:29587675

Subject Item: _:vb291653539
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:1695712

Subject Item: _:vb291653540
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:21070761

Subject Item: _:vb291653541
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:9858536

Subject Item: _:vb291653542
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:10608876

Subject Item: _:vb291653543
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:21892181

Subject Item: _:vb291653544
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:11371614

Subject Item: _:vb291653545
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:11900252

Subject Item: _:vb291653546
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:12145803

Subject Item: _:vb291653547
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:12414734

Subject Item: _:vb291653548
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:23307615

Subject Item: _:vb291653549
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:15001769

Subject Item: _:vb291653550
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:24548059

Subject Item: _:vb291653551
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:15592505

Subject Item: _:vb291653552
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:19403103

Subject Item: _:vb291653553
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:19701202

Subject Item: _:vb291653554
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:20098461

Subject Item: _:vb291653555
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:20565988

Subject Item: _:vb291653556
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:9396760

Subject Item: _:vb291653557
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:10777564

Subject Item: _:vb291653558
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:10903171

Subject Item: _:vb291653559
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:22177117

Subject Item: _:vb291653560
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:11809808

Subject Item: _:vb291653561
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:29110754

Subject Item: _:vb291653562
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:567022

Subject Item: _:vb291653563
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:19450592

Subject Item: _:vb291653564
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:19736321

Subject Item: _:vb291653565
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:11564888

Subject Item: _:vb291653566
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:22722868

Subject Item: _:vb291653567
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:12037668

Subject Item: _:vb291653568
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:25007816

Subject Item: _:vb291653569
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:30239619

Subject Item: _:vb291653570
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:10192393

Subject Item: _:vb291653571
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:10751185

Subject Item: _:vb291653572
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:11226292

Subject Item: _:vb291653573
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:22239017

Subject Item: _:vb291653574
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:22844349

Subject Item: _:vb291653575
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:22930834

Subject Item: _:vb291653576
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:14653469

Subject Item: _:vb291653577
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:15502862

Subject Item: _:vb291653578
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:15790842

Subject Item: _:vb291653579
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:16397499

Subject Item: _:vb291653580
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:17245340

Subject Item: _:vb291653581
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:18483247

Subject Item: _:vb291653582
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:20395444

Subject Item: _:vb291653583
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:20488987

Subject Item: _:vb291653584
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:25348713

Subject Item: _:vb291653585
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:17007831

Subject Item: _:vb291653586
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:27117411

Subject Item: _:vb291653587
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:29509914

Subject Item: _:vb291653588
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:29706964

Subject Item: _:vb291653589
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:19261089

Subject Item: _:vb291653590
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:19648928

Subject Item: _:vb291653591
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:6297757

Subject Item: _:vb291653592
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:9823339

Subject Item: _:vb291653593
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:21532856

Subject Item: _:vb291653594
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:11051546

Subject Item: _:vb291653595
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:12612914

Subject Item: _:vb291653596
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:23382206

Subject Item: _:vb291653597
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:25278615

Subject Item: _:vb291653598
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:27339979

Subject Item: _:vb291653599
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:18274550

Subject Item: _:vb291653600
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:7523487

Subject Item: _:vb291653601
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:9734398

Subject Item: _:vb291653602
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:9869596

Subject Item: _:vb291653603
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:21300888

Subject Item: _:vb291653604
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:10391247

Subject Item: _:vb291653605
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:10615124

Subject Item: _:vb291653606
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:21688022

Subject Item: _:vb291653607
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:22761195

Subject Item: _:vb291653608
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:12154040

Subject Item: _:vb291653609
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:15102707

Subject Item: _:vb291653610
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:24232249

Subject Item: _:vb291653611
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:26030748

Subject Item: _:vb291653612
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:27066525

Subject Item: _:vb291653613
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:19124014

Subject Item: _:vb291653614
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:19243219

Subject Item: _:vb291653615
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:11819864

Subject Item: _:vb291653616
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:22615920

Subject Item: _:vb291653617
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:22703285

Subject Item: _:vb291653618
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:15221008

Subject Item: _:vb291653619
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:15542433

Subject Item: _:vb291653620
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:16056258

Subject Item: _:vb291653621
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:16504081

Subject Item: _:vb291653622
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:26645562

Subject Item: _:vb291653623
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:17110329

Subject Item: _:vb291653624
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:17468756

Subject Item: _:vb291653625
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:27471255

Subject Item: _:vb291653626
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:28273069

Subject Item: _:vb291653627
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:19336570

Subject Item: _:vb291653628
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:19563763

Subject Item: _:vb291653629
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:33632315

Subject Item: _:vb291653630
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:20049725

Subject Item: _:vb291653631
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:8259518

Subject Item: _:vb291653632
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:22209504

Subject Item: _:vb291653633
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:22527717

Subject Item: _:vb291653634
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:23478383

Subject Item: _:vb291653635
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:23812904

Subject Item: _:vb291653636
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:24209998

Subject Item: _:vb291653637
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:24511467

Subject Item: _:vb291653638
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:26276632

Subject Item: _:vb291653639
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:17615082

Subject Item: _:vb291653640
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:19676123

Subject Item: _:vb291653641
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:7958926

Subject Item: _:vb291653642
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:8861899

Subject Item: _:vb291653643
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:9749964

Subject Item: _:vb291653644
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:11004485

Subject Item: _:vb291653645
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:21995959

Subject Item: _:vb291653646
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:22855427

Subject Item: _:vb291653647
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:23032722

Subject Item: _:vb291653648
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:12420222

Subject Item: _:vb291653649
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:15372092

Subject Item: _:vb291653650
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:17532558

Subject Item: _:vb291653651
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:1996784

Subject Item: _:vb291653652
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:19619491

Subject Item: _:vb291653653
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:19808100

Subject Item: _:vb291653654
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:9407037

Subject Item: _:vb291653655
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:10330456

Subject Item: _:vb291653656
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:11429295

Subject Item: _:vb291653657
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:22271799

Subject Item: _:vb291653658
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:22617420

Subject Item: _:vb291653659
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:22706340

Subject Item: _:vb291653660
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:12183361

Subject Item: _:vb291653661
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:23153532

Subject Item: _:vb291653662
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:23446353

Subject Item: _:vb291653663
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:14695885

Subject Item: _:vb291653664
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:15131783

Subject Item: _:vb291653665
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:25732745

Subject Item: _:vb291653666
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:20051105

Subject Item: _:vb291653667
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:10485468

Subject Item: _:vb291653668
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:22072985

Subject Item: _:vb291653669
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:22138822

Subject Item: _:vb291653670
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:22331131

Subject Item: _:vb291653671
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:24413398

Subject Item: _:vb291653672
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:25527186

Subject Item: _:vb291653673
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:17139285

Subject Item: _:vb291653674
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:18283316

Subject Item: _:vb291653675
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:18536716

Subject Item: _:vb291653676
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:19681821

Subject Item: _:vb291653677
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:20364088

Subject Item: _:vb291653678
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:22575959

Subject Item: _:vb291653679
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:14668450

Subject Item: _:vb291653680
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:16481354

Subject Item: _:vb291653681
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:28482069

Subject Item: _:vb291653682
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:28802143

Subject Item: _:vb291653683
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:31057614

Subject Item: _:vb291653684
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:31382142

Subject Item: _:vb291653685
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:10555149

Subject Item: _:vb291653686
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:11431689

Subject Item: _:vb291653687
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:25603931

Subject Item: _:vb291653688
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:16909111

Subject Item: _:vb291653689
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:17117926

Subject Item: _:vb291653690
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:17868096

Subject Item: _:vb291653691
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:29121666

Subject Item: _:vb291653692
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:19165146

Subject Item: _:vb291653693
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:19487454

Subject Item: _:vb291653694
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:32714922

Subject Item: _:vb291653695
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:19933147

Subject Item: _:vb291653696
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:7909785

Subject Item: _:vb291653697
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:8781995

Subject Item: _:vb291653698
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:9707445

Subject Item: _:vb291653699
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:9843981

Subject Item: _:vb291653700
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:22075725

Subject Item: _:vb291653701
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:11979277

Subject Item: _:vb291653702
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:24326621

Subject Item: _:vb291653703
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:19686689

Subject Item: _:vb291653704
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:21693646

Subject Item: _:vb291653705
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:21927002

Subject Item: _:vb291653706
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:11389839

Subject Item: _:vb291653707
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:11507052

Subject Item: _:vb291653708
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:24247718

Subject Item: _:vb291653709
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:15818483

Subject Item: _:vb291653710
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:28493289

Subject Item: _:vb291653711
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:19322650

Subject Item: _:vb291653712
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:7588051

Subject Item: _:vb291653713
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:20110496

Subject Item: _:vb291653714
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:8692869

Subject Item: _:vb291653715
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:20670162

Subject Item: _:vb291653716
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:9428790

Subject Item: _:vb291653717
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:9646500

Subject Item: _:vb291653718
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:11432765

Subject Item: _:vb291653719
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:22617424

Subject Item: _:vb291653720
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:12015971

Subject Item: _:vb291653721
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:23449223

Subject Item: _:vb291653722
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:23774734

Subject Item: _:vb291653723
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:15056615

Subject Item: _:vb291653724
rdf:type: n2:RelevantBibliographicResource
n2:RelevantScore: 2
n2:hasRelevantPaperId: n3:15133499