. . _:b320207270 . _:b320207202 . . . . . _:b320207193 . _:b320207182 . . _:b320207184 . _:b320207212 . _:b320207194 . _:b320207238 . . . _:b320207280 . . _:b320207179 . _:b320207151 . . . _:b320207295 . _:b320207257 . _:b320207186 . _:b320207206 . . _:b320207265 . . _:b320207217 . . _:b320207277 . . . . . _:b320207204 . _:b320207228 . . . _:b320207220 . . _:b320207188 . _:b320207240 . . _:b320207147 . _:b320207288 . . _:b320207158 . . . _:b320207219 . . . . . . _:b320207208 . . . . . . _:b1373002 . _:b320207149 "4"^^ . _:b320207148 "4"^^ . _:b320207287 . _:b320207151 "4"^^ . _:b320207150 "4"^^ . . . . _:b320207147 "5"^^ . _:b320207145 "6"^^ . . _:b320207146 "5"^^ . _:b320207157 "3"^^ . . _:b320207156 "3"^^ . . _:b320207159 "3"^^ . _:b320207177 . _:b320207158 "3"^^ . . _:b320207153 "4"^^ . _:b320207203 . . _:b320207152 "4"^^ . . _:b320207155 "3"^^ . _:b320207154 "3"^^ . _:b320207165 "3"^^ . _:b1373003 "300011 00) according to detailed protocols (Pinkel et al, >>1998<<) with some modifications (Alers et al, 1999)." . _:b320207164 "3"^^ . _:b320207213 . _:b320207167 "3"^^ . . _:b320207166 "3"^^ . . . _:b320207161 "3"^^ . . . _:b320207160 "3"^^ . _:b320207218 . . _:b320207167 . _:b320207163 "3"^^ . _:b320207235 . . _:b320207162 "3"^^ . _:b320207173 "3"^^ . . _:b320207172 "3"^^ . _:b320207175 "3"^^ . . _:b320207174 "3"^^ . _:b320207239 . . _:b320207169 "3"^^ . . _:b320207168 "3"^^ . _:b320207230 . _:b320207171 "3"^^ . . . _:b320207170 "3"^^ . _:b320207227 . _:b320207181 "3"^^ . _:b320207180 "3"^^ . _:b320207273 . _:b320207251 . . _:b320207183 "2"^^ . _:b320207169 . _:b320207182 "3"^^ . . _:b320207177 "3"^^ . _:b320207242 . _:b320207176 "3"^^ . . _:b320207179 "3"^^ . _:b320207178 "3"^^ . _:b320207236 . _:b320207189 "2"^^ . . _:b320207188 "2"^^ . _:b320207234 . _:b320207195 . _:b320207191 "2"^^ . _:b320207190 "2"^^ . _:b320207185 "2"^^ . _:b320207184 "2"^^ . _:b320207272 . _:b320207187 "2"^^ . _:b320207186 "2"^^ . . _:b320207197 "2"^^ . _:b320207149 . _:b320207196 "2"^^ . _:b320207183 . . _:b320207199 "2"^^ . _:b320207198 "2"^^ . . _:b320207193 "2"^^ . _:b320207250 . _:b320207192 "2"^^ . . _:b320207196 . . . _:b320207195 "2"^^ . _:b1373004 . _:b320207194 "2"^^ . _:b320207205 "2"^^ . _:b320207204 "2"^^ . _:b320207207 "2"^^ . . _:b320207154 . _:b1373001 . _:b320207146 . _:b320207206 "2"^^ . _:b1373001 . _:b320207201 "2"^^ . _:b1373002 . _:b320207200 "2"^^ . _:b1373003 . _:b320207149 . _:b320207203 "2"^^ . _:b320207254 . "10.1038%2Fsj.bjc.6602889" . _:b320207197 . _:b320207148 . _:b320207202 "2"^^ . _:b320207151 . . _:b320207213 "2"^^ . _:b320207286 . _:b320207150 . _:b320207212 "2"^^ . _:b320207245 . _:b320207150 . _:b320207233 . _:b320207145 . _:b320207215 "2"^^ . _:b320207166 . . _:b1373004 "300011 00) according to detailed protocols (Pinkel et al, 1998) with some modifications (Alers et al, >>1999<<). All clones (three replicates for each probe) were spotted in randomised fashion across 48 subarrays, each containing 270 spots and hybridised for 48\u201372\u2009h at 37\u00B0C on an orbital shaker (300\u2009rpm) in a humidified chamber with 2\u2009\u03BCg" . _:b320207214 "2"^^ . _:b320207147 . _:b320207223 . _:b320207209 "2"^^ . _:b320207266 . _:b320207146 . _:b320207201 . _:b320207208 "2"^^ . _:b320207174 . _:b320207157 . _:b320207211 "2"^^ . _:b320207160 . _:b320207161 . _:b320207156 . _:b320207162 . _:b320207210 "2"^^ . _:b320207163 . _:b320207164 . _:b320207165 . _:b320207159 . _:b320207166 . _:b320207221 "2"^^ . _:b320207167 . _:b320207152 . _:b320207153 . _:b320207158 . _:b320207154 . _:b320207220 "2"^^ . _:b320207285 . _:b320207155 . _:b320207156 . _:b320207157 . _:b320207153 . _:b320207158 . _:b320207223 "2"^^ . _:b320207189 . _:b320207159 . _:b320207145 . _:b320207152 . _:b320207146 . _:b320207222 "2"^^ . _:b320207147 . _:b320207148 . _:b320207149 . _:b320207155 . _:b320207150 . _:b320207217 "2"^^ . _:b320207151 . _:b320207154 . _:b320207281 . _:b320207216 "2"^^ . _:b320207211 . _:b320207165 . _:b320207219 "2"^^ . _:b320207225 . _:b320207164 . _:b320207218 "2"^^ . _:b320207271 . _:b320207167 . _:b320207229 "2"^^ . _:b320207166 . _:b320207228 "2"^^ . _:b320207241 . _:b320207237 . _:b320207161 . _:b320207231 "2"^^ . _:b320207176 . _:b320207160 . _:b320207230 "2"^^ . . _:b320207163 . _:b320207225 "2"^^ . _:b320207258 . . . _:b320207162 . _:b320207224 "2"^^ . _:b320207172 . _:b320207244 . _:b320207283 . . . _:b320207173 . _:b320207227 "2"^^ . _:b320207224 . _:b320207225 . _:b320207231 . _:b320207226 . . _:b320207172 . _:b320207227 . _:b320207226 "2"^^ . _:b320207228 . _:b320207229 . . _:b320207230 . _:b320207175 . _:b320207231 . _:b320207237 "2"^^ . _:b320207216 . . _:b320207246 . _:b320207217 . _:b320207218 . _:b320207174 . _:b320207219 . _:b320207236 "2"^^ . _:b320207220 . _:b320207221 . _:b320207290 . _:b320207222 . _:b320207169 . _:b320207223 . _:b320207239 "2"^^ . _:b320207208 . _:b320207209 . . _:b320207210 . _:b320207168 . _:b320207211 . _:b320207238 "2"^^ . _:b320207212 . _:b320207213 . _:b320207214 . _:b320207171 . _:b320207215 . _:b320207233 "2"^^ . _:b320207200 . _:b320207201 . . _:b320207202 . _:b320207170 . _:b320207203 . _:b320207232 "2"^^ . _:b320207268 . _:b320207207 . _:b320207204 . _:b320207205 . _:b320207206 . _:b320207181 . _:b320207157 . _:b320207207 . _:b320207235 "2"^^ . _:b320207192 . _:b320207193 . _:b320207194 . _:b320207180 . _:b320207195 . _:b320207255 . _:b320207234 "2"^^ . _:b320207196 . _:b320207197 . . _:b320207198 . _:b320207183 . _:b320207199 . _:b320207245 "2"^^ . _:b320207184 . . _:b320207185 . _:b320207186 . _:b320207182 . _:b320207187 . _:b320207244 "2"^^ . _:b320207188 . _:b320207189 . _:b320207190 . _:b320207177 . . _:b320207191 . _:b320207247 "2"^^ . _:b320207176 . _:b320207177 . _:b320207178 . _:b320207176 . _:b320207179 . _:b320207246 "2"^^ . _:b320207180 . _:b320207181 . _:b320207182 . _:b320207179 . _:b320207183 . _:b320207241 "2"^^ . _:b320207168 . _:b320207169 . . _:b320207170 . _:b320207178 . _:b320207171 . _:b320207240 "2"^^ . _:b320207172 . _:b320207173 . _:b320207174 . _:b320207189 . _:b320207175 . _:b320207243 "2"^^ . _:b320207263 . _:b320207288 . _:b320207289 . _:b320207290 . _:b320207188 . _:b320207291 . _:b320207242 "2"^^ . _:b320207292 . _:b320207293 . . _:b320207294 . _:b320207191 . _:b320207295 . _:b320207253 "2"^^ . _:b320207280 . _:b1373004 . _:b320207281 . _:b320207282 . _:b320207190 . _:b320207283 . _:b320207252 "2"^^ . _:b320207284 . _:b320207285 . _:b320207286 . _:b320207185 . _:b320207185 . _:b320207287 . _:b320207255 "2"^^ . _:b320207272 . _:b320207273 . _:b320207274 . . _:b320207184 . _:b320207275 . _:b320207254 "2"^^ . _:b320207276 . _:b320207277 . _:b320207278 . _:b320207187 . _:b320207279 . _:b320207249 "2"^^ . _:b320207264 . _:b320207265 . _:b320207266 . _:b320207186 . _:b320207267 . _:b320207248 "2"^^ . _:b320207268 . _:b320207198 . _:b320207269 . _:b320207270 . _:b320207197 . . _:b320207271 . _:b320207251 "2"^^ . _:b320207256 . _:b320207257 . _:b320207258 . _:b320207256 . _:b320207196 . _:b320207259 . _:b320207250 "2"^^ . _:b320207260 . _:b320207261 . _:b320207262 . _:b320207199 . _:b320207263 . _:b320207261 "2"^^ . _:b320207248 . . _:b320207249 . . _:b320207278 . _:b320207198 . _:b320207250 . _:b320207251 . _:b320207260 "2"^^ . _:b320207191 . _:b320207252 . _:b320207253 . _:b320207254 . _:b320207193 . _:b320207255 . _:b320207263 "2"^^ . _:b320207240 . . _:b320207241 . _:b320207242 . _:b320207192 . _:b320207243 . _:b320207262 "2"^^ . _:b320207244 . _:b320207245 . _:b320207246 . _:b320207195 . _:b320207247 . _:b320207257 "2"^^ . _:b320207232 . _:b320207233 . _:b1373003 . _:b320207234 . _:b320207194 . _:b320207235 . _:b320207256 "2"^^ . _:b320207236 . _:b320207237 . _:b320207238 . _:b320207205 . _:b320207239 . _:b320207259 "2"^^ . . _:b320207294 . _:b320207204 . _:b320207258 "2"^^ . . _:b320207207 . . . _:b320207269 "2"^^ . _:b320207206 . . . _:b320207268 "2"^^ . _:b320207201 . _:b320207271 "2"^^ . _:b320207274 . _:b320207200 . _:b320207270 "2"^^ . _:b320207203 . _:b320207265 "2"^^ . . _:b320207202 . _:b320207264 "2"^^ . . . _:b320207213 . _:b320207267 "2"^^ . _:b320207212 . _:b320207266 "2"^^ . _:b320207215 . _:b320207277 "2"^^ . _:b320207214 . . _:b320207276 "2"^^ . . _:b320207209 . _:b320207279 "2"^^ . _:b320207208 . _:b320207243 . _:b320207278 "2"^^ . _:b320207211 . _:b320207273 "2"^^ . _:b320207210 . _:b320207272 "2"^^ . . _:b320207159 . _:b320207221 . _:b320207200 . _:b320207275 "2"^^ . _:b320207248 . _:b320207220 . _:b320207274 "2"^^ . _:b320207223 . _:b320207285 "2"^^ . _:b320207222 . _:b320207284 "2"^^ . _:b320207217 . _:b320207287 "2"^^ . . _:b320207216 . _:b320207286 "2"^^ . _:b320207219 . _:b320207281 "2"^^ . _:b320207170 . _:b320207218 . _:b320207280 "2"^^ . _:b320207229 . _:b320207283 "2"^^ . _:b320207224 . _:b320207261 . _:b1373001 _:b1373002 . _:b320207228 . _:b1373001 _:b1373003 . _:b320207282 "2"^^ . _:b1373001 _:b1373004 . _:b320207231 . _:b320207293 "2"^^ . _:b320207230 . _:b320207292 "2"^^ . . _:b320207225 . _:b320207295 "2"^^ . _:b320207224 . _:b320207294 "2"^^ . . _:b320207227 . . _:b320207289 "2"^^ . _:b320207175 . _:b320207226 . _:b320207216 . _:b320207288 "2"^^ . . _:b320207237 . . _:b320207291 "2"^^ . _:b320207236 . _:b320207290 "2"^^ . _:b320207190 . _:b320207239 . . _:b320207276 . . _:b320207238 . . _:b320207233 . . _:b320207155 . _:b320207289 . _:b320207232 . _:b320207178 . _:b320207235 . _:b320207249 . _:b320207291 . _:b320207234 . _:b320207245 . . _:b320207244 . . . _:b320207247 . _:b320207168 . _:b320207232 . . _:b320207246 . . _:b320207241 . . _:b320207165 . _:b320207210 . _:b320207240 . . _:b320207243 . _:b320207242 . _:b320207187 . _:b320207253 . _:b320207180 . _:b320207162 . _:b320207252 . . . _:b320207255 . _:b320207254 . _:b320207173 . _:b320207252 . _:b320207249 . _:b320207221 . _:b320207248 . _:b320207229 . . _:b320207251 . _:b320207164 . _:b320207250 . . _:b320207261 . . _:b320207222 . _:b320207260 . _:b320207263 . _:b320207262 . _:b320207161 . _:b320207257 . . _:b320207284 . _:b320207256 . _:b320207259 . _:b320207247 . _:b320207258 . _:b320207269 . _:b320207160 . _:b320207268 . . . _:b320207271 . _:b320207270 . . _:b320207265 . . _:b320207199 . _:b320207264 . _:b320207267 . _:b320207209 . _:b320207266 . _:b320207156 . _:b320207277 . . _:b320207276 . _:b320207279 . _:b320207278 . _:b320207273 . _:b320207205 . _:b320207272 . _:b320207275 . _:b320207274 . . _:b320207214 . _:b320207264 . _:b320207285 . . _:b320207284 . _:b320207287 . _:b320207253 . _:b320207148 . _:b320207286 . _:b320207281 . . _:b320207262 . _:b320207275 . _:b320207280 . _:b320207283 . _:b320207267 . _:b320207282 . _:b320207293 . "PMC0" . _:b320207163 . _:b320207292 . . _:b320207295 . _:b320207181 . _:b320207153 . _:b320207294 . . . . _:b320207215 . _:b320207289 . . _:b320207259 . _:b320207288 . . . _:b320207291 . _:b1373002 "All labelling reactions were performed with the Cy3 and Cy5 conjugates from the Universal Linkage System (ULS, Kreatech Biotechnology, Amsterdam the Netherlands) (Raap et al, >>2004<<) Labelling efficiency for ULS-Cy3 and ULS-Cy5 were calculated from A260 (DNA), A280 (protein), A550 (Cy3) and A649 (Cy5) after removal of unbound ULS, on a NanoDrop\u00AEND-1000 spectrophotometer (NanoDrop Technologies, Wilmington, DE, USA)." . . _:b320207290 . _:b320207226 . _:b1373001 "materials and methods" . . . . . . . _:b320207279 . _:b320207269 . . . . . . . _:b320207171 . _:b320207293 . _:b320207292 . . _:b320207260 . _:b320207282 . _:b320207152 . . . . . _:b320207145 . . _:b320207192 . .