_:b415170027 . _:b415170347 . _:b415170026 . . _:b415170037 . _:b415170036 . . _:b415169801 . . _:b415170039 . _:b415170709 . _:b415170038 . _:b415170033 . _:b415170891 . _:b415170032 . _:b415170373 . _:b415170035 . _:b415170329 . _:b415170034 . _:b415169862 . _:b415170045 . _:b415170116 . . _:b415170044 . _:b415170047 . . _:b415170089 . _:b415170165 . _:b415170046 . . _:b415170279 . _:b415170041 . _:b415170040 . . _:b415170043 . _:b415169956 . _:b415170042 . _:b415169921 . . . . _:b415170501 . . . _:b415169973 . . . . . . _:b415170667 . . _:b415170016 . _:b415170139 . _:b415170606 . _:b415170468 . . _:b415169749 . _:b415170444 . . _:b6141892 "36 We used gene-set expression analysis>>37<< to assess whether the signatures that define ES cell identity are active and related to SOX2 expression level in lung SCC tumors." . _:b415170119 . _:b415170818 . . . . . . . . . . _:b415170734 . _:b415170391 . . . _:b415170145 . . . _:b415170790 . _:b415170754 . . . . _:b415170005 . . . _:b415169720 . . _:b415170200 . _:b415170218 . . . _:b415170186 . _:b415169992 . _:b415169880 . _:b415170766 . . . . _:b415169903 . . . _:b415170597 . _:b415170875 . _:b415170596 . . _:b415170372 . _:b415170791 . . . _:b415170411 . . . . _:b415169811 . _:b415169979 . . _:b415170810 . _:b415170651 . _:b6141893 . _:b415170228 . . _:b415170399 . _:b415170035 . . . _:b415169695 . . . _:b6141888 . _:b415170540 . _:b415170868 . _:b415170374 . _:b415169933 . _:b415169786 . _:b415170041 . . _:b415170863 . . _:b415169737 . . _:b415170110 . _:b415169797 . . _:b415170639 . _:b415170475 . _:b415170887 . _:b415170783 . _:b415169953 . . _:b415169864 . . . _:b415170603 . . _:b415170109 . _:b415169889 . . _:b415170449 . . . . _:b415170296 . _:b415170161 . _:b415169708 . _:b415170138 . . _:b415170590 . _:b415170198 . . _:b415169679 . _:b415170793 . _:b415169678 . _:b415170295 . _:b415170844 . _:b415170377 . . _:b415170641 . . . _:b415169685 . _:b415170055 . _:b415169684 . . _:b415169687 . _:b415169796 . _:b415169686 . _:b415169681 . _:b415170588 . _:b415169680 . _:b415169683 . . . _:b415170082 . _:b415169682 . _:b415169803 . _:b415169693 . . _:b415169692 . . _:b415169695 . _:b6141891 "the analysis. To identify genes linked to SOX2, we identified the 10 lung SCCs with the highest and 10 lowest SOX2 expressions. To identify correlated genes, differential expression was calculated using the same package in Bioconductor.>>36<< We used gene-set expression analysis37 to assess whether the signatures that define ES cell identity are active and related to SOX2 expression level in lung SCC tumors." . _:b415170264 . _:b415169694 . _:b415170463 . . _:b415169689 . _:b415170402 . _:b415169688 . _:b415170249 . _:b415169691 . _:b415169690 . . . . . _:b415170191 . . _:b415169701 . _:b415169700 . _:b415169703 . _:b415169694 . _:b415169702 . _:b415169697 . . _:b415169696 . _:b415170051 . _:b415169699 . _:b415169698 . _:b415169838 . _:b415170751 . . _:b415169709 . _:b415169708 . _:b415169920 . . _:b415169711 . _:b415169710 . _:b415170511 . _:b415170506 . _:b415169705 . . _:b6141890 "33 We applied RMA and quantile normalization34 and the matchprobes package in the Bioconductor framework>>35<< to create one single data set." . _:b415170327 . _:b415169704 . _:b415169707 . . _:b415169706 . _:b415169717 . _:b415170551 . _:b415169857 . . . _:b415169716 . . _:b415169719 . _:b415170141 . _:b415169863 . _:b415169718 . . _:b415169713 . _:b415169712 . . _:b415169715 . _:b415170762 . . _:b415170841 . _:b415169714 . . _:b415169795 . _:b415169725 . _:b415169724 . . _:b415170093 . _:b415169727 . _:b415170336 . _:b415169726 . _:b415169721 . _:b415169720 . . _:b415169723 . _:b415169722 . _:b415169733 . . _:b415170669 . _:b415169732 . _:b415170504 . _:b415169735 . _:b415170382 . _:b415169734 . . _:b415170861 . _:b415170404 . . _:b415169729 . _:b415169728 . _:b415169731 . . _:b415169730 . _:b415170283 . _:b415169741 . . . _:b415170029 . _:b415169740 . . _:b415169743 . _:b415170077 . _:b415169742 . . _:b415169737 . . _:b415170006 . _:b415169736 . _:b415169846 . _:b415170879 . _:b415169739 . _:b415169898 . _:b415169738 . _:b415170243 . _:b415169749 . _:b415169748 . . _:b415169751 . . _:b415169750 . _:b415169745 . . _:b415170660 . . _:b415169744 . _:b415169747 . . _:b415169746 . . _:b415169983 . _:b415169757 . _:b415170239 . _:b415169756 . _:b415169759 . _:b415169758 . _:b415170383 . _:b415169753 . . _:b415169752 . . _:b415170636 . _:b415169755 . _:b415169754 . _:b415170189 . _:b415169765 . . _:b415169764 . _:b415169767 . _:b415170288 . _:b415169766 . _:b6141888 "From existing raw expression files expression data were generated using a gene-centric CDF file.>>33<< We applied RMA and quantile normalization34 and the matchprobes package in the Bioconductor framework35 to create one single data set." . _:b415169761 . _:b415169760 . _:b415169763 . . . . _:b415169762 . _:b415169773 . _:b415170688 . _:b415169772 . _:b415169775 . _:b415169818 . _:b415169774 . _:b415170122 . _:b415170720 . _:b415169769 . _:b415169989 . _:b415169768 . _:b415169771 . _:b415170297 . _:b415169770 . _:b415169781 . _:b415169934 . _:b415169780 . _:b415169783 . . _:b415169782 . _:b415169777 . _:b415169776 . . . _:b415169779 . . _:b415169778 . _:b415170733 . _:b415170349 . _:b415169789 . _:b415170369 . _:b415169788 . . _:b415169791 . _:b415169995 . _:b415170476 . _:b415169790 . _:b415170874 . _:b415169785 . _:b415170384 . _:b415169784 . _:b415170565 . _:b415169787 . _:b415170549 . _:b415169786 . _:b415170542 . . _:b415169835 . . . _:b6141882 "1 Data were analyzed using GISTIC.1,>>9<< Copy number estimates were obtained using a tangent normalization, in which tumor signal intensities are divided by signal intensities from the linear combination of normal samples that are most similar to the tumor (manuscript describing" . . _:b415170265 . . _:b415170689 . . _:b415170569 . _:b415170857 . . . . . . . _:b415170533 . . _:b415169766 . . . . . _:b415170812 . . _:b415170705 . . . . _:b415169938 . . _:b415170311 . _:b415169957 . _:b415169911 . . . . _:b415170199 . . . _:b415170448 . _:b415170450 . _:b415169743 . . . _:b415169892 . . _:b415169689 . _:b415170068 . _:b415170162 . . . _:b415169761 . . _:b415170001 . _:b415170628 . . . . . . _:b415169984 . _:b415170164 . _:b415170154 . . . _:b415169779 . _:b415170626 . _:b415170575 . _:b415170482 . _:b415170848 . . . . . _:b415170509 . _:b6141890 . _:b415170223 . _:b415170412 . . . . . . _:b415169833 . _:b415170306 . _:b415170130 . _:b415169919 . _:b415170747 . _:b415170065 . _:b415169859 . _:b415170553 . . _:b415169787 . _:b415169768 . _:b415170780 . . . . _:b415170534 . _:b415170608 . _:b415170167 . . _:b415170188 . _:b415169937 . . . _:b415170168 . _:b415170779 . _:b415170568 . _:b415170160 . _:b415169910 . _:b415170171 . _:b415170801 . _:b415170406 . _:b415170821 . _:b415169774 . _:b415169705 . . _:b415170820 . _:b415170823 . . _:b415170822 . . . _:b415170817 . _:b415170816 . . _:b415170819 . . . _:b415170818 . _:b415170398 . _:b6141894 "TMAs were stained with a polyclonal Sox2 antibody (Chemicon) at 1:5000 dilution following Dako antigen retrieval>>38<<. After staining, we scanned the TMAs with the ZEISS MIRAX Scanner (Zeiss, Oberkochen, Germany) and then used the AxioVision Software to measure the grey scale value." . _:b415170829 . _:b415170828 . _:b415170831 . . _:b415170830 . . _:b415170825 . _:b415169751 . _:b415169944 . _:b415170467 . . _:b415170824 . _:b415170053 "3"^^ . _:b415170827 . _:b415170571 . _:b415170478 . _:b415170052 "3"^^ . _:b415170826 . _:b415170058 . _:b415170055 "3"^^ . _:b415170837 . _:b415170443 . _:b415170423 . . _:b415170054 "3"^^ . _:b415170836 . _:b415170500 . . _:b415170049 "3"^^ . . _:b415170839 . _:b415170048 "3"^^ . _:b415170838 . . _:b415170051 "3"^^ . _:b415170833 . _:b415170050 "3"^^ . _:b415170832 . _:b415170893 . _:b415170061 "3"^^ . _:b415170835 . _:b415170053 . _:b415170060 "3"^^ . _:b415170834 . . _:b415170063 "3"^^ . _:b415170845 . _:b415170062 "3"^^ . _:b415169893 . _:b415170844 . . _:b415170057 "3"^^ . _:b415170847 . _:b415169969 . _:b415170056 "3"^^ . _:b415170846 . _:b415170172 . _:b415170059 "3"^^ . _:b415170841 . _:b415170497 . _:b415170058 "3"^^ . _:b415170840 . _:b415170069 "3"^^ . _:b415170843 . _:b415169913 . _:b415170068 "3"^^ . _:b415170842 . . _:b415170215 . _:b415170455 . _:b415170071 "3"^^ . _:b415170853 . _:b415170319 . _:b415170070 "3"^^ . _:b415170852 . . _:b415170065 "3"^^ . _:b415170855 . _:b415170017 . . _:b415170064 "3"^^ . _:b415170854 . _:b415170067 "3"^^ . _:b415170849 . . _:b415170066 "3"^^ . . _:b415170848 . . _:b415170077 "3"^^ . _:b415170851 . _:b415170076 "3"^^ . _:b415170850 . _:b415170079 "3"^^ . _:b415170861 . . . _:b415170078 "3"^^ . _:b415170860 . _:b415170558 . . _:b415170073 "3"^^ . _:b415170863 . _:b415170072 "3"^^ . _:b415170862 . . . _:b415170075 "3"^^ . _:b415170857 . _:b415169886 . . _:b415170856 . _:b415170074 "3"^^ . _:b415170350 . _:b415170760 . _:b415170085 "3"^^ . _:b415170859 . _:b415169851 . _:b415170084 "3"^^ . _:b415170858 . _:b415170087 "3"^^ . _:b415170869 . . _:b415170364 . . _:b415170469 . _:b415170086 "3"^^ . _:b415170868 . _:b415170846 . _:b415170781 . _:b415170081 "3"^^ . _:b415170871 . . _:b415170080 "3"^^ . _:b415170870 . . . _:b415170865 . _:b415170083 "3"^^ . . . _:b415170864 . _:b415170082 "3"^^ . _:b415170276 . _:b415170454 . . _:b415170867 . _:b415170477 . _:b415170093 "3"^^ . _:b415170526 . _:b415170092 "3"^^ . _:b415170866 . _:b6141881 "1 Data were analyzed using GISTIC.>>1<<,9 Copy number estimates were obtained using a tangent normalization, in which tumor signal intensities are divided by signal intensities from the linear combination of normal samples that are most similar to the tumor (manuscript" . _:b415170601 . _:b415170095 "3"^^ . _:b415170877 . . _:b415170094 "3"^^ . _:b415170876 . _:b415170013 . _:b415170879 . _:b415170089 "3"^^ . . _:b415170088 "3"^^ . _:b415170878 . _:b415170376 . _:b415170091 "3"^^ . _:b415170873 . _:b415170612 . _:b415170090 "3"^^ . _:b415170872 . _:b415170489 . _:b415170101 "3"^^ . _:b415170875 . _:b415170456 . . _:b415170100 "3"^^ . _:b415170874 . _:b415170445 . _:b415170103 "3"^^ . _:b415170885 . _:b415170674 . _:b415170884 . _:b415170102 "3"^^ . . _:b415170097 "3"^^ . _:b415170887 . _:b415170545 . _:b415170096 "3"^^ . _:b415170886 . _:b415170099 "3"^^ . _:b415170881 . . _:b415170098 "3"^^ . _:b415170880 . _:b415170109 "3"^^ . _:b415170883 . _:b415170108 "3"^^ . _:b415170882 . _:b415170179 . _:b415170111 "3"^^ . _:b415170893 . . _:b415170110 "3"^^ . _:b415170892 . . . _:b415170105 "3"^^ . _:b415170895 . _:b6141882 . _:b415170104 "3"^^ . _:b415170894 . _:b415170107 "3"^^ . _:b415170889 . _:b415170106 "3"^^ . _:b415170888 . . _:b415170117 "3"^^ . _:b415170891 . . _:b415170116 "3"^^ . _:b415170890 . _:b415170119 "3"^^ . _:b415170901 . _:b415169924 . _:b415170317 . _:b415170118 "3"^^ . _:b415170900 . . _:b415170002 . _:b415170032 . _:b415170113 "3"^^ . _:b415170903 . _:b415170112 "3"^^ . _:b415170902 . . _:b415170750 . _:b415170115 "3"^^ . _:b415170897 . _:b415170648 . . . _:b415170114 "3"^^ . _:b415170896 . . _:b415170125 "3"^^ . _:b415170899 . _:b415170124 "3"^^ . _:b415170898 . _:b415169988 . . _:b415170127 "3"^^ . _:b415170909 . _:b415170126 "3"^^ . _:b415170908 . _:b415170121 "3"^^ . . _:b415170120 "3"^^ . _:b415170910 . _:b415170023 . _:b415170123 "3"^^ . _:b415170905 . _:b415170122 "3"^^ . _:b415170904 . . _:b415170133 "3"^^ . _:b415170907 . . . _:b415170906 . _:b415170132 "3"^^ . _:b415170135 "3"^^ . _:b415170134 "3"^^ . _:b415170129 "3"^^ . _:b415170128 "3"^^ . _:b415170334 . _:b415170131 "3"^^ . _:b415170130 "3"^^ . _:b415170141 "3"^^ . _:b415170230 . _:b415170140 "3"^^ . _:b415170143 "3"^^ . _:b415170142 "3"^^ . . _:b415170137 "3"^^ . _:b415170474 . _:b415170136 "3"^^ . . _:b415170139 "3"^^ . . _:b415170138 "3"^^ . _:b415170799 . _:b415170149 "3"^^ . _:b415170148 "3"^^ . _:b415170819 . _:b415170151 "3"^^ . _:b415170150 "3"^^ . _:b415170536 . . _:b415170145 "3"^^ . _:b415169760 . _:b415170144 "3"^^ . _:b415170147 "3"^^ . _:b415170715 . _:b415170146 "3"^^ . . . _:b415170157 "3"^^ . . . _:b415170156 "3"^^ . _:b415170159 "3"^^ . . _:b415170717 . _:b415170158 "3"^^ . _:b415170153 "3"^^ . _:b415170152 "3"^^ . _:b415170155 "3"^^ . _:b415170154 "3"^^ . _:b415170809 . . _:b415170165 "3"^^ . . _:b415170164 "3"^^ . _:b415170595 . . _:b415170167 "3"^^ . _:b415170166 "3"^^ . . _:b415170161 "3"^^ . _:b415170692 . _:b415170160 "3"^^ . . _:b415170163 "3"^^ . _:b415170162 "3"^^ . . _:b415170173 "3"^^ . _:b415170172 "3"^^ . . _:b415170175 "3"^^ . . . _:b415170174 "3"^^ . _:b415170281 . _:b415170169 "3"^^ . . . _:b415170168 "3"^^ . . . _:b415170171 "3"^^ . . _:b415170170 "3"^^ . _:b415170205 . _:b415170181 "3"^^ . _:b415170773 . _:b415170180 "3"^^ . _:b415170183 "3"^^ . _:b415170756 . _:b415170182 "3"^^ . _:b415170177 "3"^^ . _:b415169723 . . _:b415170118 . _:b415170176 "3"^^ . _:b415169855 . . _:b415170179 "3"^^ . _:b415170178 "3"^^ . . _:b415170189 "3"^^ . . _:b415170188 "3"^^ . _:b415170059 . _:b415170191 "3"^^ . _:b415170872 . _:b415170190 "3"^^ . . _:b415170185 "3"^^ . . . _:b415170184 "3"^^ . _:b415169915 . _:b415170267 . _:b415170187 "3"^^ . . _:b415170294 . . _:b415170186 "3"^^ . . _:b415170197 "3"^^ . _:b415170196 "3"^^ . _:b415170199 "3"^^ . _:b415170198 "3"^^ . _:b415170202 . . _:b415170193 "3"^^ . _:b415170192 "3"^^ . _:b415170519 . _:b415170195 "3"^^ . _:b415170774 . _:b415170194 "3"^^ . _:b415170718 . _:b415169734 . _:b415170205 "3"^^ . . _:b415170708 . _:b415170204 "3"^^ . _:b415170207 "3"^^ . _:b415170433 . _:b415170206 "3"^^ . _:b415170657 . . _:b415170201 "3"^^ . . _:b415170200 "3"^^ . _:b415170203 "3"^^ . _:b415169976 . _:b415170202 "3"^^ . _:b415170213 "2"^^ . _:b415170212 "2"^^ . _:b415170737 . _:b415170308 . _:b415170365 . _:b415170215 "2"^^ . _:b415169840 . _:b415170108 . . _:b415170320 . _:b415170214 "2"^^ . _:b415170236 . _:b415170209 "3"^^ . . _:b415170208 "3"^^ . _:b415170211 "2"^^ . _:b415170210 "2"^^ . . _:b415170221 "2"^^ . _:b415169829 . _:b415170220 "2"^^ . . . _:b415170223 "2"^^ . _:b415170222 "2"^^ . _:b415169845 . _:b415170219 . . _:b415170217 "2"^^ . _:b415170216 "2"^^ . . _:b415170219 "2"^^ . _:b415170190 . _:b415170218 "2"^^ . . _:b415170229 "2"^^ . _:b415170228 "2"^^ . _:b415170524 . _:b415170592 . _:b415170231 "2"^^ . . _:b415170230 "2"^^ . _:b415170054 . _:b6141886 "Analysis was performed with RIGER (RNAi Gene Enrichment Ranking)>>16<<,17 to compare the effects of each construct on the four 3q26.33-amplified lines to the construct\u2019s effects in control cell lines to determine an enrichment score for each construct." . . _:b415170225 "2"^^ . . _:b415170224 "2"^^ . _:b415170290 . . _:b415170142 . _:b415170227 "2"^^ . _:b415170752 . _:b415170573 . _:b415170098 . . _:b415170226 "2"^^ . . _:b415170237 "2"^^ . _:b415170530 . _:b415170236 "2"^^ . _:b415170324 . _:b415170239 "2"^^ . _:b415170177 . . _:b415170831 . _:b415170238 "2"^^ . _:b415170233 "2"^^ . _:b415170490 . _:b415170232 "2"^^ . _:b415170235 "2"^^ . _:b415170221 . _:b415170431 . _:b415170234 "2"^^ . _:b415170076 . . _:b415170245 "2"^^ . _:b415170637 . _:b415170244 "2"^^ . . _:b415170247 "2"^^ . _:b415170638 . . . _:b415170246 "2"^^ . _:b415170241 "2"^^ . . _:b415170090 . _:b415170240 "2"^^ . . _:b415170243 "2"^^ . _:b415170242 "2"^^ . . _:b415170253 "2"^^ . _:b415169955 . . . _:b415170252 "2"^^ . . . _:b415170255 "2"^^ . _:b415170543 . _:b415170254 "2"^^ . . _:b415170249 "2"^^ . _:b415170248 "2"^^ . _:b415170251 "2"^^ . . . _:b415170250 "2"^^ . . _:b415170261 "2"^^ . . _:b415170260 "2"^^ . _:b415170060 . _:b415170263 "2"^^ . _:b415170262 "2"^^ . _:b415170257 "2"^^ . _:b415170582 . _:b415170256 "2"^^ . _:b415170510 . _:b415170259 "2"^^ . _:b415170258 "2"^^ . _:b415170269 "2"^^ . . _:b415169782 . _:b415170268 "2"^^ . _:b415170446 . . _:b415170271 "2"^^ . _:b415170270 "2"^^ . . . _:b415170359 . _:b415170265 "2"^^ . . _:b415169828 . _:b415170264 "2"^^ . _:b415169991 . . . _:b415170267 "2"^^ . _:b415170266 "2"^^ . . _:b415170277 "2"^^ . _:b415169788 . _:b415170276 "2"^^ . _:b415170665 . . _:b415170214 . . _:b415170314 . _:b415170279 "2"^^ . . _:b415170278 "2"^^ . _:b415170273 "2"^^ . . _:b415170272 "2"^^ . _:b415170275 "2"^^ . . _:b415170274 "2"^^ . _:b415170285 "2"^^ . . . _:b415170284 "2"^^ . _:b415170287 "2"^^ . _:b415169745 . _:b415169974 . _:b415170570 . _:b415170286 "2"^^ . _:b415169799 . _:b415170281 "2"^^ . _:b415170775 . _:b415170280 "2"^^ . _:b415170283 "2"^^ . _:b415170217 . . _:b415170282 "2"^^ . _:b415169850 . _:b415170293 "2"^^ . . _:b415170292 "2"^^ . _:b415170295 "2"^^ . _:b415170565 . . _:b415170294 "2"^^ . _:b415170564 . _:b415170419 . _:b415170300 . _:b415170289 "2"^^ . _:b415170567 . _:b415170346 . _:b415170288 "2"^^ . _:b415170566 . _:b415170529 . _:b415170291 "2"^^ . _:b415170561 . _:b415170290 "2"^^ . _:b415170158 . _:b415170560 . _:b415170301 "2"^^ . _:b415170563 . _:b415170300 "2"^^ . . _:b415170562 . . _:b415170303 "2"^^ . _:b415170573 . _:b415170048 . _:b415170302 "2"^^ . _:b415170572 . . _:b415170297 "2"^^ . _:b415170575 . _:b415170296 "2"^^ . . _:b415170574 . . _:b415170299 "2"^^ . _:b415170569 . _:b415170556 . . _:b415170298 "2"^^ . _:b415170568 . _:b415170695 . _:b415170309 "2"^^ . _:b415170571 . _:b415170251 . _:b415170308 "2"^^ . . _:b415170570 . _:b415170439 . _:b415170311 "2"^^ . _:b415170581 . _:b415170310 "2"^^ . _:b415170580 . _:b415170305 "2"^^ . . _:b415170583 . _:b415169699 . _:b415170304 "2"^^ . . _:b415170582 . _:b415170307 "2"^^ . _:b415170577 . _:b415170306 "2"^^ . _:b415170576 . _:b415170317 "2"^^ . _:b415170579 . _:b415170316 "2"^^ . _:b415170578 . _:b415169739 . _:b415169865 . . _:b415170414 . _:b415170319 "2"^^ . _:b415170589 . . _:b415170318 "2"^^ . _:b415170588 . . _:b415170313 "2"^^ . _:b415170591 . _:b415170579 . _:b415170312 "2"^^ . _:b415170590 . . _:b415170315 "2"^^ . _:b415170585 . _:b415170314 "2"^^ . _:b415170584 . _:b415170325 "2"^^ . _:b415170587 . _:b415170324 "2"^^ . _:b415170586 . _:b415170327 "2"^^ . _:b415170597 . _:b415170326 "2"^^ . _:b415170596 . _:b415170134 . _:b415170321 "2"^^ . . _:b415170599 . _:b415170732 . . _:b415170320 "2"^^ . . _:b415170598 . _:b415170323 "2"^^ . _:b415170593 . _:b415170322 "2"^^ . _:b415170592 . _:b415170333 "2"^^ . . _:b415170595 . _:b415170115 . _:b415170332 "2"^^ . _:b415170594 . _:b415169839 . _:b415170335 "2"^^ . _:b415170027 . _:b415170605 . . _:b415170334 "2"^^ . _:b415170604 . _:b415170329 "2"^^ . _:b415170607 . _:b415170328 "2"^^ . _:b415170606 . _:b415170331 "2"^^ . _:b415170601 . _:b415170330 "2"^^ . _:b415170600 . _:b415170341 "2"^^ . . _:b415170603 . _:b415170340 "2"^^ . _:b415170602 . _:b415170343 "2"^^ . _:b415170613 . _:b415170452 . _:b415170342 "2"^^ . _:b415170612 . . _:b415170337 "2"^^ . _:b415170615 . . _:b415170336 "2"^^ . _:b415170614 . _:b415170339 "2"^^ . _:b415169926 . _:b415170609 . _:b415170338 "2"^^ . _:b415170608 . _:b415170147 . _:b415170349 "2"^^ . _:b415170611 . _:b415169815 . _:b415170348 "2"^^ . _:b415170610 . . _:b415170351 "2"^^ . _:b415170621 . _:b415170350 "2"^^ . _:b415170825 . _:b415170620 . _:b415170345 "2"^^ . _:b415170623 . _:b415170196 . _:b415170344 "2"^^ . _:b415170622 . _:b415170347 "2"^^ . _:b415170617 . . _:b415170346 "2"^^ . _:b415170616 . _:b415170047 . _:b415170357 "2"^^ . _:b415170619 . _:b415170356 "2"^^ . _:b415170618 . _:b415170634 . _:b415170359 "2"^^ . _:b415170629 . _:b415170358 "2"^^ . _:b415170628 . _:b415169736 . _:b415170074 . _:b415170353 "2"^^ . _:b415170631 . _:b415170352 "2"^^ . _:b415170630 . _:b415170052 . _:b415170355 "2"^^ . _:b415170625 . _:b415170354 "2"^^ . . _:b415170624 . _:b415170365 "2"^^ . _:b415170627 . _:b415170364 "2"^^ . _:b415170626 . _:b415170367 "2"^^ . _:b415170637 . _:b415170494 . _:b415170366 "2"^^ . _:b415170566 . _:b415170636 . . _:b415170361 "2"^^ . _:b415170639 . _:b415170525 . _:b415170360 "2"^^ . _:b415170638 . . . _:b415170363 "2"^^ . _:b415170633 . _:b415170621 . _:b415170362 "2"^^ . _:b415170632 . . _:b415170373 "2"^^ . _:b415170635 . _:b415170473 . . _:b415170372 "2"^^ . _:b415170634 . _:b415170375 "2"^^ . _:b415170645 . _:b415170374 "2"^^ . _:b415170644 . _:b415170369 "2"^^ . _:b415170647 . _:b415170272 . . _:b415170368 "2"^^ . _:b415170646 . _:b415170371 "2"^^ . _:b415170641 . . _:b415170370 "2"^^ . _:b415170640 . . _:b415169713 . _:b415170381 "2"^^ . _:b415170574 . _:b415170643 . . _:b415170380 "2"^^ . _:b415170642 . _:b415170227 . _:b415170383 "2"^^ . . _:b415170653 . . _:b415170211 . _:b415170382 "2"^^ . _:b415170652 . _:b415170377 "2"^^ . _:b415170655 . _:b415170143 . _:b415170376 "2"^^ . . _:b415170654 . _:b415170379 "2"^^ . _:b415170649 . . _:b415170378 "2"^^ . _:b415170765 . _:b415170488 . _:b415170648 . _:b415170389 "2"^^ . _:b415170651 . _:b415170388 "2"^^ . . _:b415170650 . _:b415169867 . _:b415170391 "2"^^ . _:b415170661 . . _:b415170390 "2"^^ . _:b415170660 . _:b415170611 . _:b415170385 "2"^^ . _:b415170663 . . _:b415170384 "2"^^ . _:b415170662 . . _:b415170387 "2"^^ . _:b415170657 . _:b415170386 "2"^^ . _:b415170656 . . . _:b415170397 "2"^^ . _:b415170659 . _:b415170396 "2"^^ . _:b415170658 . . _:b415170399 "2"^^ . . _:b415170669 . _:b415170173 . _:b415170398 "2"^^ . _:b415170668 . _:b415170393 "2"^^ . _:b415170671 . _:b415170392 "2"^^ . _:b415170670 . _:b415170395 "2"^^ . _:b415170156 . _:b415170665 . _:b415170394 "2"^^ . _:b415170664 . _:b415170447 . . _:b415170405 "2"^^ . _:b415170667 . _:b415170404 "2"^^ . _:b415170666 . _:b415170407 "2"^^ . _:b415169706 . _:b415170677 . _:b415170406 "2"^^ . _:b415169940 . _:b415170676 . _:b415170513 . _:b415170401 "2"^^ . _:b415170684 . _:b415170679 . _:b415170210 . _:b415170400 "2"^^ . _:b415170678 . _:b415170403 "2"^^ . _:b415170673 . _:b415169832 . _:b415170402 "2"^^ . _:b415170672 . _:b415170341 . _:b415170413 "2"^^ . _:b415170712 . _:b415170675 . . _:b415170412 "2"^^ . . _:b415170674 . . _:b415170415 "2"^^ . _:b415170685 . _:b415170414 "2"^^ . _:b415170684 . _:b415170563 . . _:b415170409 "2"^^ . _:b415170687 . _:b415170679 . . . _:b415170408 "2"^^ . . _:b415169690 . _:b415170686 . _:b415170193 . _:b415170836 . _:b415170411 "2"^^ . . _:b415170681 . . _:b415170410 "2"^^ . . _:b415170680 . _:b415170421 "2"^^ . _:b415170683 . . . _:b415170420 "2"^^ . _:b415170682 . . _:b415170313 . _:b415170423 "2"^^ . . _:b415170693 . _:b415169905 . _:b415169735 . _:b415170422 "2"^^ . _:b415170692 . . . _:b415170417 "2"^^ . _:b415170630 . _:b415170695 . _:b415170416 "2"^^ . _:b415170694 . _:b415170419 "2"^^ . _:b415170689 . _:b415170418 "2"^^ . _:b415170688 . _:b415169965 . _:b415170429 "2"^^ . _:b415170691 . _:b415170428 "2"^^ . _:b415170690 . _:b415169966 . _:b415170431 "2"^^ . . _:b415170701 . . _:b415169732 . _:b415170430 "2"^^ . _:b415170700 . . _:b415170425 "2"^^ . _:b415170703 . _:b415170007 . _:b415170424 "2"^^ . . . _:b415170702 . _:b415170224 . _:b415170427 "2"^^ . _:b415170697 . . _:b415170426 "2"^^ . _:b415170696 . _:b415170437 "2"^^ . _:b415170699 . _:b415170436 "2"^^ . _:b415170698 . _:b415170439 "2"^^ . _:b415170709 . _:b415170438 "2"^^ . _:b415170708 . _:b415170433 "2"^^ . _:b415169986 . _:b415170711 . _:b415170432 "2"^^ . _:b415170710 . _:b415170435 "2"^^ . _:b415170705 . . _:b415170434 "2"^^ . _:b415170704 . _:b415170445 "2"^^ . _:b415170440 . _:b415170707 . _:b415170444 "2"^^ . _:b415170011 . _:b415170706 . _:b415170465 . _:b415170447 "2"^^ . _:b415170717 . _:b415170446 "2"^^ . _:b415170716 . . _:b415170441 "2"^^ . _:b415170719 . _:b415170440 "2"^^ . _:b415170718 . _:b415170443 "2"^^ . _:b415170713 . . _:b415170442 "2"^^ . _:b415170712 . _:b415170805 . _:b415170453 "2"^^ . _:b415170715 . _:b415170452 "2"^^ . _:b415170714 . _:b415170455 "2"^^ . . _:b415170725 . _:b415169752 . _:b415170127 . _:b415170454 "2"^^ . _:b415170724 . _:b415170449 "2"^^ . _:b415170910 . _:b415170727 . _:b415170448 "2"^^ . . _:b415170726 . . . _:b415170451 "2"^^ . . _:b415170721 . _:b6141883 "of amplifications. Only amplifications exceeding log2 copy number ratio of 0.848 above diploid for amplifications or of 0.737 below diploid for deletions were included as has been standard in copy-number analyses with SNP arrays.>>1<< This copy-number threshold for amplifications is lower than what is conventionally used to score FISH as done below." . . _:b415170450 "2"^^ . _:b415170720 . _:b415170461 "2"^^ . _:b415170723 . . _:b415170460 "2"^^ . _:b415170722 . _:b415170463 "2"^^ . _:b415170733 . . _:b415170462 "2"^^ . _:b415170732 . _:b415170457 "2"^^ . _:b415170735 . _:b415170456 "2"^^ . _:b415170734 . _:b415170150 . _:b415170163 . _:b415170459 "2"^^ . _:b415170729 . _:b415170458 "2"^^ . _:b415170759 . _:b415170728 . _:b415170469 "2"^^ . _:b415170731 . . _:b415170468 "2"^^ . _:b415170730 . _:b415170471 "2"^^ . _:b415170741 . _:b415170470 "2"^^ . _:b415170740 . _:b415170465 "2"^^ . _:b415170743 . _:b415170464 "2"^^ . _:b415170850 . _:b415170280 . _:b415170742 . . _:b415170429 . . _:b415170467 "2"^^ . _:b415170737 . _:b415170591 . _:b415170466 "2"^^ . _:b415170736 . _:b415170477 "2"^^ . _:b415170739 . _:b415170476 "2"^^ . _:b415169696 . _:b415170738 . . _:b415170479 "2"^^ . _:b415170019 . _:b415170749 . _:b415170478 "2"^^ . . . _:b415170748 . _:b415170473 "2"^^ . _:b415170751 . . . _:b415170472 "2"^^ . _:b415170750 . . _:b415169724 . _:b415170475 "2"^^ . . . _:b415170745 . . . _:b415170474 "2"^^ . . _:b415170744 . _:b415170485 "2"^^ . _:b415170747 . _:b415170039 . _:b415170484 "2"^^ . _:b415170746 . . _:b415170487 "2"^^ . . _:b415170699 . _:b415170757 . _:b415170486 "2"^^ . _:b415170756 . _:b415170481 "2"^^ . _:b415170312 . _:b415170759 . _:b415170480 "2"^^ . . _:b415170758 . . _:b415170483 "2"^^ . . _:b415170753 . _:b415170512 . _:b415170482 "2"^^ . _:b415170752 . . _:b415170493 "2"^^ . _:b415169712 . _:b415170755 . _:b415170849 . _:b415170492 "2"^^ . _:b415170754 . . _:b415170495 "2"^^ . _:b415170765 . _:b415170494 "2"^^ . _:b415170764 . . _:b415170489 "2"^^ . _:b415170767 . . _:b415170123 . _:b415169824 . _:b415170488 "2"^^ . _:b415170766 . . _:b415170348 . _:b415170491 "2"^^ . _:b415170761 . _:b415170490 "2"^^ . _:b415170760 . _:b415170501 "2"^^ . _:b415170763 . . _:b415170500 "2"^^ . _:b415170762 . _:b415170503 "2"^^ . _:b415170773 . _:b415170502 "2"^^ . _:b415170772 . . _:b415170497 "2"^^ . _:b415170775 . _:b415170496 "2"^^ . . _:b415170774 . _:b415170499 "2"^^ . _:b415170769 . _:b415170498 "2"^^ . _:b415170768 . _:b415170509 "2"^^ . _:b415170771 . _:b415170253 . _:b415170792 . _:b415170508 "2"^^ . _:b415170136 . _:b415170137 . _:b415170770 . _:b415170138 . _:b415170139 . _:b415170511 "2"^^ . _:b415170140 . _:b415170141 . _:b415170781 . _:b415170142 . _:b415170143 . _:b415170510 "2"^^ . . _:b415170128 . _:b415170129 . _:b415170780 . _:b415170130 . _:b415170131 . _:b415170505 "2"^^ . _:b415170132 . _:b415170133 . _:b415170783 . . _:b415170134 . . _:b415170180 . _:b415170135 . _:b415170504 "2"^^ . _:b415170120 . _:b415170121 . _:b415170782 . _:b415170122 . _:b415170123 . _:b415170507 "2"^^ . _:b415170124 . _:b415170125 . _:b415170777 . _:b415170126 . _:b415170127 . _:b415170506 "2"^^ . _:b415170112 . _:b415170776 . _:b415170113 . _:b415170114 . _:b415170115 . _:b415169767 . _:b415170517 "2"^^ . _:b415170116 . _:b415170779 . _:b415170117 . _:b415170118 . _:b415170119 . _:b415170516 "2"^^ . _:b415170168 . _:b415170778 . _:b415170169 . _:b415170170 . _:b415170171 . _:b415170519 "2"^^ . _:b415170172 . _:b415170789 . _:b415170173 . _:b415170174 . _:b415170175 . _:b415170518 "2"^^ . _:b415170160 . _:b415170788 . _:b415170161 . _:b415170162 . _:b415170163 . _:b415170183 . _:b415170513 "2"^^ . _:b415170164 . _:b415170791 . _:b415170165 . _:b415170166 . _:b415170167 . _:b415170512 "2"^^ . _:b415170152 . _:b415170790 . _:b415170153 . _:b415170154 . _:b415170155 . _:b415170515 "2"^^ . _:b415170156 . _:b415170785 . _:b415170157 . . _:b415170158 . _:b415170159 . _:b415170514 "2"^^ . _:b415170144 . _:b415170784 . _:b415170145 . _:b415169954 . _:b415170146 . _:b415170147 . _:b415170525 "2"^^ . _:b415170148 . _:b415170787 . _:b415170149 . _:b415170150 . _:b415170151 . _:b415170524 "2"^^ . _:b415170701 . _:b415170072 . _:b415170786 . _:b415170073 . _:b415170074 . . _:b415170075 . . _:b415170076 . _:b415170527 "2"^^ . _:b415170797 . _:b415170077 . _:b415170078 . _:b415170079 . _:b415170526 "2"^^ . _:b415169780 . _:b415170064 . _:b415170796 . _:b415170065 . _:b415170066 . _:b415170067 . _:b415170521 "2"^^ . _:b415170068 . _:b415170799 . _:b415170069 . _:b415170070 . _:b415170397 . _:b415170071 . _:b415170520 "2"^^ . _:b415170056 . _:b415170798 . _:b415170057 . _:b415170058 . . _:b415170059 . . _:b415170060 . _:b415170523 "2"^^ . _:b415170793 . _:b415170061 . _:b415170062 . _:b415170063 . _:b415170522 "2"^^ . _:b415170048 . _:b415170792 . _:b415170049 . _:b415170169 . _:b415170050 . _:b415170051 . _:b415170533 "2"^^ . _:b415170052 . _:b415170795 . _:b415170053 . _:b415170054 . _:b415170055 . _:b415170823 . _:b415170580 . _:b415170104 . _:b415170532 "2"^^ . _:b415170794 . _:b415170105 . _:b415169890 . _:b415170106 . _:b415170107 . _:b415169773 . _:b415170803 . _:b415170108 . _:b415170535 "2"^^ . _:b415170805 . _:b415170109 . _:b415170110 . _:b415170642 . _:b415170111 . _:b415170323 . _:b415170096 . _:b415170534 "2"^^ . _:b415170804 . _:b415170097 . _:b415170098 . _:b415170099 . _:b415170529 "2"^^ . _:b415170100 . _:b415170807 . _:b415170101 . _:b415170102 . _:b415170103 . _:b415170528 "2"^^ . _:b415170088 . _:b415170806 . _:b415170089 . _:b415170361 . _:b415170090 . _:b415170091 . _:b415170531 "2"^^ . _:b415170092 . _:b415170801 . _:b415170093 . . _:b415170094 . . _:b415170095 . _:b415170530 "2"^^ . _:b415170080 . _:b415170800 . _:b415170081 . _:b415170082 . _:b415170083 . _:b415170541 "2"^^ . _:b415170084 . _:b415170803 . _:b415170085 . _:b415170086 . _:b415170087 . . _:b415170264 . _:b415170540 "2"^^ . _:b415170802 . _:b415170265 . _:b415170266 . _:b415170267 . _:b415170543 "2"^^ . . _:b415170268 . _:b415170813 . _:b415170269 . _:b415169702 . _:b415170270 . _:b415170271 . . _:b415170542 "2"^^ . _:b415170256 . _:b415170812 . . _:b415170257 . _:b415170258 . _:b415170259 . _:b415170537 "2"^^ . _:b415170260 . _:b415170815 . _:b415170043 . _:b415170261 . _:b415170262 . _:b415170263 . . . _:b415170248 . _:b415170536 "2"^^ . _:b415170814 . _:b415170249 . . _:b415170250 . _:b415170251 . _:b415170539 "2"^^ . _:b415170252 . _:b415170809 . _:b415170253 . _:b415170254 . _:b415170255 . . _:b415170538 "2"^^ . _:b415170240 . _:b415170808 . . _:b415170241 . _:b415170028 . _:b415170242 . _:b415170243 . _:b415170776 . _:b415170244 . _:b415170549 "2"^^ . _:b415170811 . _:b415170245 . _:b415170246 . . _:b415170247 . . . _:b415170296 . _:b415170548 "2"^^ . _:b415170810 . _:b415170297 . _:b415170298 . . _:b415170299 . _:b415170085 . _:b415170551 "2"^^ . _:b415170300 . _:b415170301 . _:b415170302 . _:b415170303 . _:b415170550 "2"^^ . _:b415170288 . _:b415170289 . _:b415170290 . . _:b415170291 . _:b415170545 "2"^^ . _:b415170292 . _:b415170293 . _:b415170294 . . _:b415170295 . _:b415170544 "2"^^ . _:b415170280 . _:b415170281 . . _:b415170282 . _:b415170283 . . _:b415170547 "2"^^ . _:b415170284 . _:b415170285 . _:b415170010 . _:b415170286 . _:b415169895 . _:b415170287 . . _:b415170546 "2"^^ . . _:b415170272 . _:b415170273 . _:b415170274 . _:b415170275 . _:b415170557 "2"^^ . _:b415170276 . _:b415170277 . . _:b415170278 . _:b415170333 . _:b415170279 . _:b415170556 "2"^^ . _:b415170200 . _:b415170201 . _:b415170789 . _:b415170202 . _:b415170498 . _:b415170203 . _:b415170822 . _:b415170559 "2"^^ . _:b415170204 . _:b415170205 . _:b415170206 . . _:b415170207 . _:b415170558 "2"^^ . _:b415170192 . _:b415170193 . _:b415170194 . _:b415170839 . _:b415170195 . _:b415170553 "2"^^ . _:b415170196 . _:b415170197 . _:b415170198 . _:b415170199 . _:b415170552 "2"^^ . _:b415170184 . _:b415170185 . _:b415170186 . _:b415170187 . _:b415170555 "2"^^ . _:b415170188 . _:b415170189 . _:b415170190 . _:b415170191 . _:b415170554 "2"^^ . _:b415170176 . _:b415170177 . _:b415169874 . _:b415170178 . . _:b415170179 . _:b415170180 . _:b415170181 . _:b415170182 . _:b415170183 . _:b415170232 . _:b415170233 . _:b415169756 . _:b415170234 . _:b415170235 . _:b415170236 . . _:b415170237 . _:b415170238 . _:b415170239 . _:b415170224 . _:b415170225 . _:b415170226 . _:b415170227 . _:b415169872 . . _:b415170228 . _:b415170516 . . _:b415170229 . _:b415170230 . _:b415170231 . _:b415170216 . . _:b415170217 . _:b415170218 . _:b415170219 . . _:b415170220 . _:b415170221 . _:b415170222 . _:b415170223 . _:b415170208 . _:b415170209 . . _:b415170210 . . _:b415170211 . _:b415170212 . _:b415170213 . _:b415170214 . _:b415170888 . _:b415170215 . _:b415170392 . _:b415170393 . . _:b415170394 . _:b415170395 . _:b415170396 . _:b415170397 . _:b415170398 . _:b415170399 . _:b415170384 . _:b415170385 . . _:b415170386 . . _:b415170387 . _:b415170388 . _:b415170389 . _:b415170390 . _:b415170391 . _:b415170376 . . _:b415170377 . _:b415170378 . _:b415170417 . _:b415170379 . _:b415170685 . _:b415170380 . _:b415170174 . _:b415170381 . _:b415170382 . _:b415170383 . _:b415170368 . . _:b415170369 . . _:b415170370 . _:b415170371 . _:b415170372 . . _:b415170373 . . _:b415170374 . _:b415170375 . _:b415170424 . _:b415170425 . _:b415170426 . _:b415170427 . _:b415170428 . _:b415170429 . _:b415170430 . _:b6141892 . . _:b415170431 . _:b415170416 . _:b415170417 . . _:b415170807 . _:b415170418 . _:b415170419 . _:b415170420 . _:b415170421 . _:b415170422 . _:b415170423 . _:b415170408 . _:b415170409 . _:b415170797 . _:b415170410 . _:b415170411 . . _:b415170412 . _:b415170432 . _:b415170413 . _:b415170414 . _:b415170415 . _:b415170400 . _:b415170254 . _:b415170401 . _:b415170245 . _:b415170402 . _:b415170403 . _:b415170404 . _:b415170405 . _:b415170406 . . _:b415170407 . _:b415170034 . _:b415170328 . _:b415170329 . _:b415170330 . _:b415170682 . _:b415170331 . _:b415170332 . _:b415170333 . _:b415169789 . _:b415170334 . _:b415170335 . _:b415170263 . _:b415170320 . _:b415170321 . . _:b415170322 . _:b415170323 . _:b415170869 . _:b415170324 . _:b415170325 . _:b415170326 . _:b415170327 . . _:b415170312 . _:b415170313 . _:b415170314 . _:b415170315 . . _:b415170316 . _:b415170317 . _:b415170318 . . _:b415170319 . . _:b415170304 . _:b415170305 . _:b415170306 . _:b415170307 . _:b415170149 . _:b415170308 . _:b415170309 . _:b415170310 . _:b415170311 . _:b415170360 . _:b415170587 . _:b415170361 . _:b415170727 . _:b415170362 . _:b415170363 . _:b415170364 . _:b415170365 . _:b415170366 . _:b415169775 . _:b415170367 . _:b415170352 . _:b415170353 . _:b415170354 . _:b415170355 . _:b415170356 . _:b415170357 . . _:b415170358 . _:b415170359 . . . _:b415170496 . _:b415170344 . _:b415170345 . _:b415170578 . _:b415170877 . _:b415170346 . _:b415170347 . . _:b415170348 . _:b415170349 . _:b415170350 . _:b415170351 . _:b415170336 . _:b415170337 . _:b415170609 . _:b415170338 . _:b415170209 . _:b415170339 . _:b415170340 . _:b415170341 . . _:b415170342 . _:b415170343 . _:b415170520 . _:b415170521 . _:b415170522 . _:b415170523 . _:b415170906 . _:b415170524 . _:b415170854 . _:b415170525 . _:b415170526 . _:b415170527 . _:b415170512 . _:b415170513 . _:b415170514 . _:b415170515 . _:b415170516 . _:b415170517 . _:b415170518 . _:b415170519 . . _:b415170504 . . _:b415170505 . _:b415170506 . _:b415170507 . _:b415170508 . _:b415170509 . _:b415170510 . _:b415170511 . _:b415170581 . _:b415170496 . _:b415170497 . . _:b415170498 . _:b415170499 . _:b415170500 . _:b415170501 . _:b415170502 . _:b415170503 . _:b415170552 . . _:b415170553 . . _:b415170554 . _:b415170555 . _:b415170556 . _:b415170557 . _:b415170558 . _:b415170559 . . _:b415170544 . . _:b415170545 . _:b415170546 . _:b415170547 . _:b415169757 . _:b415170548 . _:b415170549 . _:b415170550 . _:b415170551 . _:b415170536 . _:b415170537 . _:b415170538 . . _:b415170539 . _:b415170540 . _:b415170541 . _:b415170894 . _:b415170542 . _:b415170543 . _:b415170528 . _:b415170274 . _:b415170529 . _:b415170530 . _:b415170531 . _:b415170532 . _:b415170533 . _:b415170534 . _:b415170535 . _:b415170456 . . . _:b415170457 . _:b415170458 . _:b415169929 . _:b415170459 . _:b415170460 . _:b415170461 . _:b415170462 . _:b415170463 . _:b415170448 . _:b415169916 . _:b415170449 . _:b415170450 . _:b415170451 . _:b415170452 . _:b415170453 . _:b415170719 . _:b415170454 . _:b415170455 . _:b415170440 . _:b415169861 . _:b415170441 . _:b415170442 . _:b415170443 . _:b415170444 . _:b415170445 . _:b415170286 . _:b415170446 . _:b415170447 . _:b415170735 . _:b415170432 . _:b415170433 . _:b415170434 . _:b415170435 . _:b415170436 . _:b415170437 . _:b415170832 . _:b415170438 . _:b415170439 . _:b415170488 . _:b415170489 . . _:b415170490 . _:b415170491 . _:b415170492 . _:b415170493 . _:b415170494 . _:b415170495 . _:b415170480 . _:b415170481 . . _:b415170482 . _:b415170483 . _:b415170484 . _:b415170485 . _:b415170486 . _:b415170487 . _:b415170472 . _:b415170473 . _:b415170474 . _:b415170475 . _:b415170523 . _:b415170476 . _:b415170477 . _:b415170478 . _:b415170479 . _:b415170464 . _:b415170465 . _:b415170466 . _:b415170467 . _:b415170468 . _:b415170469 . _:b415170470 . _:b415170471 . _:b415170871 . . . . . _:b415170710 . . . . _:b415170396 . . _:b415170388 . . _:b415169808 . _:b415170259 . _:b415170238 . _:b415170390 . . _:b415169950 . . _:b415170020 . _:b415169821 . _:b415169729 . _:b415170080 . _:b415170104 . . . _:b415170144 . . . . _:b415170240 . _:b415169894 . _:b415169752 . _:b415170057 . _:b415169753 . _:b415169754 . _:b415169755 . _:b415169756 . _:b415169757 . _:b415169758 . _:b415169759 . _:b415169744 . _:b415169745 . _:b415170624 . _:b415169746 . _:b415169747 . _:b415169748 . _:b415169749 . _:b415169750 . _:b415169751 . _:b415169736 . _:b415169737 . _:b415170677 . _:b415169738 . _:b415169739 . . _:b415169740 . . _:b415169741 . _:b415169742 . _:b415169743 . _:b415169728 . _:b415169729 . _:b415169730 . _:b415169731 . _:b415169732 . . _:b415169733 . _:b415169734 . _:b415169735 . _:b415169882 . _:b415169784 . _:b415170786 . _:b415169785 . _:b415169786 . _:b415169787 . _:b415169788 . _:b415169789 . _:b415170050 . _:b415169790 . _:b415169791 . _:b415169776 . . _:b415169777 . _:b415169778 . _:b415170507 . _:b415169779 . _:b415169780 . _:b415169781 . _:b415169782 . . _:b415169783 . . _:b415169768 . _:b415169769 . _:b415169770 . _:b415169771 . _:b415169772 . _:b415169773 . _:b415169774 . _:b415169775 . _:b415169760 . _:b415169761 . . _:b415169762 . _:b415170493 . _:b415169763 . _:b415169764 . _:b415169765 . _:b415169766 . _:b415169767 . _:b415169688 . _:b415169689 . _:b415169690 . _:b415169691 . _:b415169692 . . _:b415169693 . _:b415169694 . _:b415169695 . _:b415169680 . _:b415169681 . _:b415169682 . _:b415169683 . _:b415169684 . _:b415169685 . _:b415169686 . _:b415169687 . _:b415169869 . . _:b415169678 . _:b415169679 . . _:b415170289 . _:b415169720 . _:b415169721 . _:b415169722 . _:b415169723 . _:b415169724 . _:b415169725 . . _:b415169971 . _:b415169726 . _:b415169727 . _:b415169712 . _:b415169713 . . _:b415169714 . . _:b415169715 . _:b415169716 . _:b415170672 . _:b415169717 . _:b415169718 . . _:b415169719 . _:b415169704 . _:b415169705 . _:b415170394 . _:b415170026 . _:b415169706 . _:b415170318 . _:b415169707 . _:b415169708 . _:b415170321 . _:b415170521 . . _:b415169709 . _:b415169710 . _:b415169711 . _:b415169696 . _:b415169697 . _:b415169698 . _:b415169699 . _:b415169700 . _:b415170097 . _:b415169701 . _:b415169702 . _:b415169703 . _:b415169880 . _:b415169881 . _:b415169882 . _:b415169883 . _:b415169884 . _:b415169684 . _:b415169885 . _:b415169886 . _:b415169887 . _:b415169872 . _:b415169873 . _:b415169874 . _:b415169875 . _:b415169876 . _:b415169877 . _:b415169878 . _:b415169879 . _:b415169864 . _:b415169865 . _:b415169680 "36"^^ . _:b415169866 . _:b415169867 . _:b415169868 . _:b415169869 . _:b415169870 . _:b415169871 . _:b415169856 . _:b415169857 . . _:b415169858 . _:b415169859 . _:b415169802 . _:b415169860 . _:b415169861 . _:b415169862 . _:b415169863 . . _:b415169912 . _:b415169682 "26"^^ . _:b415170698 . _:b415169679 "39"^^ . _:b415169913 . _:b415169914 . _:b415169683 "25"^^ . _:b415169915 . _:b415169681 "26"^^ . _:b415169916 . _:b415169917 . _:b415169918 . _:b415169726 . _:b415169919 . _:b415169904 . _:b415169905 . . _:b415169906 . . _:b415169907 . _:b415169908 . _:b415169909 . _:b415170470 . _:b415169910 . _:b415169911 . _:b415169896 . . _:b415169897 . . _:b415169898 . _:b415169899 . _:b415169678 "46"^^ . _:b415169900 . _:b415169901 . _:b415169902 . _:b415169684 "25"^^ . _:b415169903 . _:b415169687 "21"^^ . _:b415170548 . _:b415169888 . . _:b415169889 . _:b415169685 "24"^^ . _:b415169890 . _:b415169686 "21"^^ . _:b415169891 . . _:b415169892 . _:b415169689 "18"^^ . _:b415169893 . . _:b415169894 . _:b415169836 . _:b415169895 . _:b415169812 . _:b415169816 . _:b415169688 "19"^^ . _:b415169817 . _:b415169818 . _:b415169819 . _:b415169691 "18"^^ . _:b415169820 . _:b415169821 . _:b415169822 . . _:b415170661 . _:b415169823 . _:b415169690 "18"^^ . _:b415169808 . . _:b415169809 . _:b415169810 . _:b415169811 . _:b415169812 . _:b415169813 . . _:b415169814 . . _:b415169815 . _:b415170739 . _:b415169800 . _:b415169692 "18"^^ . _:b415169801 . _:b415169802 . _:b415169693 "17"^^ . _:b415169803 . _:b415169804 . _:b415169805 . _:b415169806 . _:b415169694 "17"^^ . _:b415169807 . _:b415169792 . _:b415169793 . _:b415169731 . _:b415169794 . . _:b415169795 . _:b415169695 "17"^^ . _:b415169796 . _:b415170503 . _:b415169797 . _:b415169696 "16"^^ . _:b415169798 . _:b415169914 . _:b415169799 . _:b415170030 . _:b415169848 . _:b415170741 . _:b415169849 . _:b415169697 "16"^^ . _:b415169850 . _:b415169851 . _:b415169852 . _:b415169853 . _:b415169698 "16"^^ . _:b415169854 . _:b415169855 . _:b415169840 . _:b415169841 . _:b415169699 "16"^^ . _:b415169842 . _:b415169770 . _:b415169843 . . _:b415169844 . _:b415169700 "15"^^ . _:b415169845 . _:b415169846 . . _:b415169847 . _:b415169832 . _:b415169701 "15"^^ . _:b415169833 . _:b415169834 . . _:b415169835 . _:b415169702 "14"^^ . _:b415169836 . _:b415169837 . _:b415169838 . _:b415169839 . _:b415169703 "14"^^ . _:b415169824 . _:b415169825 . _:b415169826 . _:b415169827 . . . _:b415169828 . _:b415169704 "14"^^ . _:b415169829 . _:b415169711 "12"^^ . _:b415169830 . _:b415169831 . . _:b415170008 . _:b415169705 "14"^^ . _:b415170009 . _:b415169710 "12"^^ . _:b415170010 . _:b415170011 . _:b415170012 . . _:b415170013 . _:b415169709 "12"^^ . _:b415170014 . _:b415170015 . _:b415170000 . _:b415170001 . _:b415170393 . _:b415170002 . _:b415169708 "12"^^ . _:b415170003 . _:b415170004 . _:b415170604 . . _:b415170005 . _:b415170410 . _:b415170006 . _:b415169707 "12"^^ . _:b415170515 . _:b415170007 . _:b415169992 . _:b415169993 . _:b415169706 "12"^^ . _:b415169994 . _:b415169995 . _:b415169996 . . _:b415169997 . _:b415169998 . _:b415169999 . _:b415169984 . _:b415169985 . _:b415170537 . _:b415169986 . _:b415169987 . _:b415169988 . . _:b415169989 . _:b415169719 "11"^^ . . _:b415169990 . _:b415169991 . _:b415170040 . _:b415170041 . _:b415169718 "12"^^ . _:b415170042 . _:b415170043 . _:b415170044 . _:b415170045 . _:b415169717 "12"^^ . _:b415170046 . _:b415170047 . _:b415170032 . _:b415170033 . . _:b415169716 "12"^^ . _:b415170034 . _:b415170035 . _:b415170036 . _:b415170037 . _:b415169715 "12"^^ . _:b415170038 . _:b415170039 . _:b415170024 . _:b415170025 . _:b415169714 "12"^^ . _:b415170026 . _:b415170126 . _:b415170027 . _:b415170028 . _:b415170029 . . _:b415170030 . _:b415169713 "12"^^ . _:b415170031 . _:b415170016 . _:b415170522 . _:b415170017 . _:b415169712 "12"^^ . _:b415170018 . _:b415170019 . _:b415170856 . _:b415169727 "10"^^ . _:b415170020 . _:b415170021 . _:b415170022 . _:b415170023 . _:b415169726 "10"^^ . _:b415169944 . _:b415169945 . _:b415169946 . _:b415169947 . _:b415169948 . _:b415169725 "11"^^ . _:b415169949 . _:b415169950 . . _:b415169951 . _:b415169936 . _:b415169724 "11"^^ . _:b415169937 . _:b415169938 . _:b415169939 . _:b415169940 . _:b415169723 "11"^^ . _:b415169941 . _:b415169942 . . _:b415169943 . _:b415169928 . _:b415169722 "11"^^ . _:b415169769 . _:b415169929 . _:b415169930 . _:b415170613 . _:b415169931 . _:b415169932 . _:b415170824 . _:b415169721 "11"^^ . _:b415169933 . _:b415169934 . _:b415169935 . . . _:b415169920 . _:b415169720 "11"^^ . _:b415169921 . _:b415169922 . _:b415169923 . _:b415169735 "10"^^ . _:b415169924 . . _:b415169925 . _:b415170231 . _:b415169926 . . _:b415169927 . _:b415169734 "10"^^ . _:b415169976 . _:b415169977 . _:b415169978 . _:b415169979 . _:b415170042 . _:b415169980 . _:b415169733 "10"^^ . _:b415169981 . _:b415169982 . _:b415170753 . _:b415169983 . _:b415169732 "10"^^ . _:b415169968 . _:b415169969 . _:b415170000 . _:b415169970 . _:b415169971 . _:b415169731 "10"^^ . _:b415169972 . . _:b415169973 . _:b415169974 . _:b415169975 . . _:b415169960 . _:b415169730 "10"^^ . _:b415169961 . _:b415169962 . _:b415169963 . _:b415170527 . _:b415169964 . _:b415169729 "10"^^ . _:b415170817 . _:b415169965 . . _:b415169966 . _:b415169967 . _:b415170892 . _:b415169728 "10"^^ . _:b415169952 . . _:b415169953 . _:b415169954 . _:b415169955 . _:b415169956 . . _:b415169957 . _:b415169958 . _:b415169742 "9"^^ . _:b415169959 . . _:b415169743 "9"^^ . _:b415169740 "9"^^ . _:b415170100 . . _:b415169741 "9"^^ . _:b415169738 "9"^^ . _:b415170656 . . . _:b415169739 "9"^^ . _:b415169737 "10"^^ . _:b415169949 . _:b415170166 . _:b415169736 "10"^^ . _:b415169750 "9"^^ . . _:b415169751 "9"^^ . _:b415169748 "9"^^ . . _:b415169749 "9"^^ . _:b415170690 . _:b415169746 "9"^^ . . . _:b415169747 "9"^^ . _:b415169744 "9"^^ . . _:b415169745 "9"^^ . . . _:b415169758 "8"^^ . _:b415169961 . _:b415170322 . _:b415169759 "8"^^ . . _:b415169756 "8"^^ . _:b415169757 "8"^^ . . . . _:b415169754 "9"^^ . _:b415169755 "9"^^ . _:b415169752 "9"^^ . _:b415169753 "9"^^ . . _:b415169704 . _:b415169766 "8"^^ . . _:b415169767 "8"^^ . _:b415169764 "8"^^ . . . _:b415169765 "8"^^ . _:b415170424 . _:b415170724 . . . _:b415169762 "8"^^ . . _:b415169763 "8"^^ . _:b415169683 . . _:b415169760 "8"^^ . _:b415170212 . . _:b415169761 "8"^^ . _:b415169774 "8"^^ . . . . _:b415169775 "8"^^ . _:b415170255 . _:b415170114 . _:b415169772 "8"^^ . . _:b415169773 "8"^^ . _:b415170182 . _:b415169770 "8"^^ . _:b415169771 "8"^^ . _:b415169768 "8"^^ . _:b415169755 . _:b415169769 "8"^^ . _:b415170771 . . _:b415169782 "7"^^ . . _:b415169727 . _:b415169783 "7"^^ . _:b415169771 . _:b415169780 "7"^^ . _:b415170744 . _:b415169781 "7"^^ . _:b415169778 "7"^^ . _:b415169779 "7"^^ . _:b415169776 "7"^^ . . . _:b415169777 "7"^^ . . _:b415169790 "7"^^ . . _:b415170728 . _:b415169791 "7"^^ . _:b415170337 . _:b415169788 "7"^^ . . _:b415170808 . _:b415170024 . _:b415169789 "7"^^ . . . _:b415169786 "7"^^ . . _:b415169787 "7"^^ . . _:b415169784 "7"^^ . _:b415170014 . _:b415169785 "7"^^ . _:b415169798 "6"^^ . . _:b415169799 "6"^^ . _:b415169730 . . _:b415169796 "6"^^ . _:b415169762 . _:b415169797 "6"^^ . _:b415169714 . _:b415169794 "6"^^ . . _:b415169795 "6"^^ . . _:b415169792 "7"^^ . . _:b415170645 . . _:b415169793 "7"^^ . _:b415170363 . _:b415169806 "6"^^ . _:b415170902 . _:b415169807 "6"^^ . . _:b415169804 "6"^^ . . _:b415169805 "6"^^ . _:b415170800 . . _:b415169802 "6"^^ . _:b415170659 . _:b415169803 "6"^^ . _:b415169800 "6"^^ . _:b415169801 "6"^^ . . _:b415169814 "6"^^ . _:b415169815 "6"^^ . _:b415169875 . _:b415169812 "6"^^ . . _:b415169813 "6"^^ . _:b415170716 . . _:b415169810 "6"^^ . _:b415170619 . _:b415169811 "6"^^ . _:b415169814 . _:b415169808 "6"^^ . . _:b415169809 "6"^^ . _:b415169798 . _:b415169820 "6"^^ . . _:b415169823 "5"^^ . _:b415169821 "6"^^ . _:b415169822 "5"^^ . . _:b415169818 "6"^^ . _:b415169819 "6"^^ . _:b415169816 "6"^^ . _:b415169817 "6"^^ . _:b415170232 . _:b415169829 "5"^^ . _:b415169828 "5"^^ . _:b415170102 . _:b415170250 . _:b415170903 . _:b415169831 "5"^^ . _:b415169830 "5"^^ . _:b415169825 "5"^^ . _:b415170044 . . _:b415169824 "5"^^ . _:b415170094 . _:b415169827 "5"^^ . _:b415169837 . _:b415169826 "5"^^ . _:b415169837 "5"^^ . _:b415170878 . _:b415170181 . _:b415169836 "5"^^ . _:b415169839 "5"^^ . . _:b415170301 . . _:b415169838 "5"^^ . _:b415170155 . . _:b415169833 "5"^^ . . _:b415169832 "5"^^ . _:b415169835 "5"^^ . . _:b415169834 "5"^^ . _:b415170226 . _:b415169845 "5"^^ . _:b415170342 . _:b415170237 . _:b415170890 . _:b415169844 "5"^^ . _:b415170409 . _:b415169847 "5"^^ . _:b415169908 . _:b415170472 . _:b415169846 "5"^^ . _:b415169841 "5"^^ . . _:b415169840 "5"^^ . _:b415169843 "5"^^ . _:b415169842 "5"^^ . _:b415169853 "5"^^ . _:b415169852 "5"^^ . _:b415169855 "5"^^ . . _:b415169854 "5"^^ . _:b415170898 . _:b415169849 "5"^^ . _:b415170748 . _:b415169848 "5"^^ . _:b415169851 "5"^^ . . _:b415169850 "5"^^ . _:b415169861 "5"^^ . . _:b415170121 . _:b415169860 "5"^^ . _:b415170763 . _:b415169863 "5"^^ . _:b415169862 "5"^^ . _:b415169857 "5"^^ . _:b415170855 . _:b415169975 . _:b415169856 "5"^^ . _:b415169859 "5"^^ . _:b415169858 "5"^^ . _:b415169747 . _:b415169869 "5"^^ . _:b415169868 "5"^^ . _:b415169871 "5"^^ . . _:b415169870 "5"^^ . _:b415170605 . _:b415169680 . _:b415169865 "5"^^ . . _:b415169864 "5"^^ . _:b415169867 "5"^^ . _:b415169866 "5"^^ . _:b415169816 . . . _:b415169877 "4"^^ . _:b415169876 "5"^^ . . _:b415169879 "4"^^ . _:b415170460 . _:b415170700 . _:b415170653 . _:b415169878 "4"^^ . _:b415169781 . . _:b415170079 . _:b415169873 "5"^^ . _:b415169872 "5"^^ . _:b415170257 . _:b415169875 "5"^^ . . _:b415169874 "5"^^ . . _:b415169885 "4"^^ . . _:b415169884 "4"^^ . _:b6141879 . _:b415169887 "4"^^ . _:b415170355 . . . . _:b415170835 . _:b415169886 "4"^^ . _:b415169881 "4"^^ . _:b415170479 . _:b415169880 "4"^^ . _:b415169883 "4"^^ . . _:b415169882 "4"^^ . _:b415169893 "4"^^ . _:b415169892 "4"^^ . _:b415169895 "4"^^ . . _:b415170064 . _:b415169894 "4"^^ . . _:b415170564 . _:b415169889 "4"^^ . _:b415169888 "4"^^ . _:b415169891 "4"^^ . _:b6141885 "AALE cells were generated as previously described.>>18<< HCC95, NCI-H1355, NCI-H2009 and NCI-H1437 were provided by J.D.M. NCI-H520 cells were purchased from ATCC." . _:b415169890 "4"^^ . . _:b415169901 "4"^^ . . _:b415169900 "4"^^ . _:b415169903 "4"^^ . _:b415169902 "4"^^ . _:b415169790 . _:b415169897 "4"^^ . _:b415169896 "4"^^ . _:b415169899 "4"^^ . _:b415170680 . _:b415169898 "4"^^ . _:b415169909 "4"^^ . _:b415169908 "4"^^ . _:b415170847 . _:b415170546 . _:b415169911 "4"^^ . _:b415170499 . _:b415170585 . _:b415169910 "4"^^ . _:b415169905 "4"^^ . _:b415169936 . _:b415169904 "4"^^ . . _:b415170820 . _:b415170073 . _:b415169907 "4"^^ . . _:b415169906 "4"^^ . . _:b415169701 . _:b415169917 "4"^^ . . _:b415169916 "4"^^ . . _:b415169919 "4"^^ . _:b415169918 "4"^^ . _:b415169913 "4"^^ . _:b415169912 "4"^^ . _:b415170157 . _:b415169915 "4"^^ . _:b415169914 "4"^^ . _:b415170899 . _:b415169925 "4"^^ . . _:b415169924 "4"^^ . _:b415169927 "4"^^ . . _:b415169926 "4"^^ . . _:b415170132 . . _:b415169921 "4"^^ . _:b415169920 "4"^^ . _:b415169923 "4"^^ . _:b415169759 . _:b415169922 "4"^^ . . _:b415169933 "4"^^ . _:b415169943 . . _:b415169932 "4"^^ . . . _:b415170018 . . _:b415169935 "4"^^ . . _:b415169934 "4"^^ . . _:b415169929 "4"^^ . _:b415169928 "4"^^ . _:b415169931 "4"^^ . _:b415169930 "4"^^ . . _:b415169941 "4"^^ . . _:b415169758 . _:b415169940 "4"^^ . _:b415169943 "4"^^ . _:b415170107 . . _:b415169942 "4"^^ . _:b415169932 . . _:b415169937 "4"^^ . _:b415169906 . . _:b415169936 "4"^^ . . _:b415169939 "4"^^ . . . . _:b415169938 "4"^^ . . _:b415169949 "4"^^ . _:b415169948 "4"^^ . _:b415170275 . . _:b415169951 "4"^^ . . _:b415169950 "4"^^ . _:b415169945 "4"^^ . _:b415169944 "4"^^ . . _:b415169947 "4"^^ . _:b415170484 . _:b415169946 "4"^^ . . . _:b415169957 "4"^^ . _:b415169956 "4"^^ . _:b415169902 . _:b415169841 . _:b415169959 "4"^^ . _:b415169958 "4"^^ . _:b415169953 "4"^^ . _:b415169952 "4"^^ . _:b415169955 "4"^^ . _:b415170131 . _:b415170379 . . _:b415169954 "4"^^ . _:b415169965 "4"^^ . _:b415169964 "4"^^ . _:b415169764 . _:b415169967 "4"^^ . _:b415170883 . . . _:b415169966 "4"^^ . _:b415169961 "4"^^ . _:b415169960 "4"^^ . _:b415170770 . . _:b415169963 "4"^^ . _:b415169970 . . _:b415169962 "4"^^ . _:b415169973 "4"^^ . _:b415170784 . _:b415169972 "4"^^ . _:b415170629 . _:b415169975 "4"^^ . _:b415169974 "4"^^ . _:b415170599 . _:b415169969 "4"^^ . . . _:b415169968 "4"^^ . _:b415169971 "4"^^ . _:b415169970 "4"^^ . _:b415169981 "4"^^ . _:b415170764 . _:b415169980 "4"^^ . . _:b415169983 "4"^^ . _:b415170461 . _:b415170644 . _:b415169982 "4"^^ . . _:b415169977 "4"^^ . . _:b415169976 "4"^^ . _:b415170304 . _:b415169979 "4"^^ . . . _:b415169978 "4"^^ . . _:b415170795 . _:b415169989 "4"^^ . . _:b415169988 "4"^^ . . _:b415169991 "3"^^ . _:b415169990 "3"^^ . _:b415170434 . _:b415170650 . _:b415169985 "4"^^ . . _:b415170137 . . _:b415169984 "4"^^ . _:b415169987 "4"^^ . _:b415169986 "4"^^ . _:b415169997 "3"^^ . _:b415169996 "3"^^ . _:b415169999 "3"^^ . _:b415170646 . _:b415169998 "3"^^ . . _:b415169993 "3"^^ . _:b415170829 . _:b415169992 "3"^^ . _:b415169995 "3"^^ . _:b415169994 "3"^^ . _:b415170005 "3"^^ . _:b415170731 . _:b415170084 . _:b415170004 "3"^^ . _:b415170007 "3"^^ . _:b415170437 . _:b415170778 . _:b415170560 . _:b415170006 "3"^^ . . _:b415170001 "3"^^ . _:b415170767 . _:b415170000 "3"^^ . _:b415170213 . _:b415170726 . _:b415170003 "3"^^ . . . _:b415170002 "3"^^ . _:b415170561 . _:b415170013 "3"^^ . . _:b415170012 "3"^^ . _:b415170015 "3"^^ . _:b415170014 "3"^^ . . _:b415170009 "3"^^ . _:b415170015 . _:b415169948 . . _:b415170008 "3"^^ . _:b415170011 "3"^^ . _:b415170010 "3"^^ . _:b415170021 "3"^^ . . _:b415170020 "3"^^ . . . _:b415170023 "3"^^ . _:b415170022 "3"^^ . _:b415170428 . _:b415170017 "3"^^ . . _:b415170016 "3"^^ . . . _:b415170019 "3"^^ . . . _:b415170018 "3"^^ . _:b415169968 . _:b415170029 "3"^^ . . _:b415170028 "3"^^ . _:b415170031 "3"^^ . _:b415170030 "3"^^ . _:b415170225 . _:b415170025 "3"^^ . . _:b415170430 . _:b415170024 "3"^^ . . _:b415170027 "3"^^ . _:b415170284 . . . _:b415170026 "3"^^ . . _:b415170037 "3"^^ . . _:b415169827 . _:b415170036 "3"^^ . _:b415169980 . . _:b415170039 "3"^^ . . _:b415170246 . _:b415170038 "3"^^ . _:b415170648 . _:b415170649 . . _:b415170033 "3"^^ . _:b415170650 . _:b415170651 . _:b415170652 . _:b415170653 . _:b415170654 . _:b415170032 "3"^^ . . _:b415170655 . _:b415170640 . _:b415170641 . . _:b415170035 "3"^^ . _:b415170642 . _:b415170643 . _:b415170644 . _:b415170645 . _:b415170646 . _:b415170034 "3"^^ . . _:b415170647 . _:b415170632 . _:b415170633 . _:b415170634 . _:b415170045 "3"^^ . _:b415170635 . _:b415170636 . _:b415170637 . _:b415170638 . _:b415170044 "3"^^ . _:b415170639 . _:b415170624 . _:b415170420 . _:b415170625 . _:b415170626 . _:b415170047 "3"^^ . _:b415170627 . _:b415170628 . _:b415170629 . _:b415170630 . _:b415170046 "3"^^ . _:b415170631 . _:b415170680 . _:b415170742 . _:b415170681 . _:b415170682 . _:b415170041 "3"^^ . _:b415170683 . _:b415169693 . _:b415170684 . _:b415170685 . _:b415170686 . _:b415170040 "3"^^ . _:b415170687 . _:b415170672 . _:b415170091 . _:b415170673 . _:b415170674 . _:b415170043 "3"^^ . . _:b415170675 . . _:b415170676 . _:b415170220 . _:b415170677 . _:b415170678 . _:b415170042 "3"^^ . _:b415170679 . . _:b415170664 . _:b415170665 . _:b415170666 . _:b415170667 . _:b415170668 . _:b415170669 . _:b415170670 . _:b415170671 . _:b415170865 . _:b415170656 . _:b415170657 . _:b415170658 . _:b415170659 . _:b415170660 . _:b415170661 . _:b415170662 . _:b415170663 . _:b415170584 . _:b415170585 . _:b415170586 . _:b415170587 . _:b415170588 . _:b415170589 . _:b415170590 . _:b415170591 . _:b415170576 . _:b415170577 . _:b415170370 . _:b415170578 . _:b415170579 . _:b415170580 . _:b415170581 . _:b415170582 . _:b415170583 . _:b415170568 . _:b415170569 . _:b415170570 . _:b415170571 . _:b415170572 . _:b415170573 . . _:b415170574 . _:b415170575 . _:b415170560 . _:b415170451 . _:b415170561 . _:b415170562 . _:b415170563 . _:b415170247 . _:b415170907 . _:b415170564 . _:b415170565 . _:b415170566 . _:b415170567 . _:b415170616 . _:b415170617 . _:b415170758 . . _:b415170618 . _:b415170619 . _:b415170620 . _:b415170197 . _:b415170621 . _:b415170622 . _:b415170623 . _:b415170866 . _:b415169870 . _:b415170608 . _:b415169977 . _:b415170609 . _:b415170269 . _:b415170610 . _:b415170675 . _:b415170611 . _:b415170612 . . _:b415170613 . . _:b415170614 . _:b415170615 . . _:b415170600 . _:b415170601 . _:b415170602 . _:b415170615 . _:b415170603 . _:b415170604 . _:b415170605 . _:b415170606 . _:b415170607 . _:b415170592 . _:b415170593 . _:b415170594 . _:b415170595 . . _:b415170596 . . . _:b415170597 . _:b415170598 . _:b415170599 . _:b415170776 . _:b415170777 . . _:b415170778 . _:b415169996 . _:b415170779 . _:b415170331 . _:b415170780 . _:b415170781 . _:b415170782 . _:b415170783 . . _:b415170768 . _:b415170769 . . _:b415170770 . _:b415170771 . _:b415170520 . _:b415170772 . _:b415170773 . _:b415170774 . _:b415170775 . _:b415170760 . _:b415170761 . . _:b415170762 . _:b415170062 . _:b415170763 . _:b415170764 . _:b415170765 . _:b415170766 . _:b415170767 . _:b415170271 . _:b415170752 . _:b415170753 . _:b415170713 . _:b415170754 . _:b415170755 . _:b415170756 . _:b415170757 . _:b415170758 . _:b415170833 . _:b415170759 . _:b415170078 . _:b415170808 . _:b415170809 . _:b415170485 . _:b415170810 . _:b415170811 . _:b415170812 . _:b415170813 . _:b415170814 . _:b415170815 . _:b415170800 . _:b415170801 . _:b415170802 . _:b415170803 . _:b415170804 . _:b415170805 . _:b415169685 . _:b415170806 . _:b415170807 . _:b415170792 . _:b415170793 . _:b415170794 . _:b415170795 . _:b415170796 . _:b415170797 . _:b415170798 . _:b415170799 . _:b415170784 . _:b415170785 . _:b415169946 . _:b415170786 . _:b415170787 . _:b415170788 . _:b415170789 . _:b415170790 . _:b415170791 . _:b415170712 . _:b415170713 . _:b415170714 . _:b415170715 . _:b415170716 . . _:b415170717 . _:b415170718 . _:b415170719 . _:b415170704 . _:b415170705 . _:b415169825 . _:b415169899 . _:b415170706 . _:b415170707 . _:b415170708 . _:b415170709 . _:b415170710 . _:b415170711 . _:b415170696 . _:b415170697 . _:b415170698 . _:b415170699 . _:b415170700 . _:b415170701 . _:b415170702 . _:b415170703 . _:b415170794 . _:b415170688 . _:b415170689 . _:b415170690 . _:b415170691 . _:b415170692 . . _:b415170693 . _:b415170694 . _:b415170695 . _:b415170744 . _:b415170745 . _:b415170746 . _:b415170747 . _:b415170748 . _:b415170749 . _:b415170750 . _:b415170751 . _:b415170736 . _:b415170737 . . _:b415170738 . _:b415170739 . . _:b415170740 . _:b415170741 . _:b415170742 . _:b415170743 . _:b415170728 . _:b415170729 . _:b415170730 . . _:b415170731 . _:b415170732 . _:b415170733 . _:b415170734 . _:b415169935 . _:b415170735 . _:b415170720 . _:b415170721 . _:b415170722 . . _:b415170723 . _:b415170724 . _:b415170725 . _:b415170726 . _:b415170727 . _:b415170904 . _:b415170260 . _:b415170905 . _:b415170906 . _:b415170907 . . _:b415170908 . _:b415170909 . _:b415170910 . _:b415170896 . _:b415170897 . _:b415170898 . _:b415170899 . _:b415170900 . _:b415170901 . _:b415170902 . _:b415170903 . _:b415170888 . _:b415170889 . _:b415170890 . _:b415170891 . _:b415169738 . _:b415170892 . _:b415170893 . _:b415170894 . _:b415170895 . _:b415170880 . _:b415170881 . _:b415170882 . _:b415170883 . _:b415170884 . _:b415170885 . _:b415170886 . _:b415170887 . . _:b415170387 . . . . _:b415170244 . _:b415170136 . . _:b415170840 . _:b415170841 . . _:b415170842 . _:b415170658 . _:b415170843 . _:b415170844 . _:b415170845 . _:b415170846 . _:b415170649 . _:b415170847 . _:b415170832 . _:b415170833 . _:b415170834 . _:b415170835 . _:b415170836 . _:b415170837 . _:b415170838 . _:b415170839 . _:b415170824 . _:b415170825 . _:b415170826 . _:b415170827 . _:b415169763 . _:b415170828 . _:b415170829 . _:b415170830 . _:b415170831 . . _:b415170816 . _:b415170817 . _:b415170818 . _:b415170819 . _:b415170820 . _:b415170821 . _:b415170822 . _:b415170823 . _:b415170152 . _:b415170872 . _:b415170873 . _:b415170874 . . _:b415170875 . _:b415170876 . _:b415170877 . _:b415170125 . _:b415170878 . _:b415170879 . _:b415170864 . _:b415170676 . _:b415170865 . _:b415170866 . _:b415170867 . _:b415170868 . _:b415170869 . _:b415170870 . . _:b415170871 . _:b415170856 . _:b415170857 . _:b415170576 . _:b415170798 . _:b415170858 . _:b415170859 . _:b415170860 . _:b415170886 . . _:b415170861 . _:b415170862 . _:b415170863 . . _:b415170848 . _:b415170849 . . _:b415170850 . . _:b415170851 . _:b415170358 . _:b415170852 . . _:b415170853 . . _:b415170854 . _:b415170855 . _:b415169947 . . . . _:b415170252 . _:b415170070 . _:b6141886 . . _:b6141880 "DNA was genotyped using the Sty I chip of the 500K Human Mapping Arrays (Affymetrix Inc).>>1<< Data were analyzed using GISTIC." . . _:b415169990 . _:b415170755 . . . . . . . . _:b415170654 . . _:b415169912 . _:b415170730 . _:b415169691 . _:b415170777 . . . _:b415170834 . . _:b415170554 . . _:b415170583 . . . . _:b415170185 . _:b415170338 . . _:b415170565 "2"^^ . _:b415170564 "2"^^ . _:b415170567 "2"^^ . _:b415170566 "2"^^ . _:b415169721 . _:b415170561 "2"^^ . _:b415170248 . _:b415170560 "2"^^ . _:b415170563 "2"^^ . . _:b415169718 . . _:b415170562 "2"^^ . _:b415170559 . _:b415170640 . . _:b415170573 "2"^^ . _:b415170633 . _:b415170572 "2"^^ . _:b415170575 "2"^^ . . . _:b415170574 "2"^^ . _:b415170589 . _:b415170557 . _:b415170569 "2"^^ . _:b415170056 . _:b415170069 . _:b415170568 "2"^^ . . . _:b415170571 "2"^^ . _:b415170570 "2"^^ . _:b415170581 "2"^^ . _:b415170049 . _:b415170385 . _:b415170580 "2"^^ . _:b415170583 "2"^^ . . _:b415170582 "2"^^ . _:b415169987 . _:b415170577 "2"^^ . _:b415170576 "2"^^ . _:b415170579 "2"^^ . . _:b415170578 "2"^^ . _:b415170589 "2"^^ . _:b415169967 . _:b415170175 . "PMC0" . _:b415170588 "2"^^ . _:b415169776 . _:b415170591 "2"^^ . _:b415170590 "2"^^ . _:b415170585 "2"^^ . _:b415170584 "2"^^ . _:b415170531 . _:b415170025 . _:b415170587 "2"^^ . _:b415170814 . _:b415170586 "2"^^ . _:b415170597 "2"^^ . . _:b415170596 "2"^^ . _:b415170421 . _:b415170599 "2"^^ . _:b415169900 . _:b415170598 "2"^^ . _:b415170170 . _:b415170593 "2"^^ . _:b415170592 "2"^^ . _:b415169848 . . _:b415170595 "2"^^ . . _:b415170909 . _:b415170594 "2"^^ . . _:b415170605 "2"^^ . _:b415170604 "2"^^ . _:b415169978 . _:b415170607 "2"^^ . . _:b415170345 . _:b415170606 "2"^^ . . . . _:b415170601 "2"^^ . _:b415170600 "2"^^ . . _:b415170603 "2"^^ . _:b415169884 . _:b415170602 "2"^^ . _:b415170466 . _:b415170613 "2"^^ . _:b415170071 . _:b415170612 "2"^^ . _:b415170615 "2"^^ . _:b415170614 "2"^^ . _:b415170483 . _:b415170609 "2"^^ . . . _:b415170608 "2"^^ . _:b415170611 "2"^^ . _:b415170610 "2"^^ . _:b415170621 "2"^^ . . _:b415169907 . . _:b415170092 . _:b415170620 "2"^^ . . _:b415170623 "2"^^ . _:b415170622 "2"^^ . _:b415170885 . . _:b415170617 "2"^^ . _:b415170788 . _:b415170616 "2"^^ . . _:b415170619 "2"^^ . _:b415170618 "2"^^ . _:b415170629 "2"^^ . _:b415170628 "2"^^ . _:b415170631 "2"^^ . _:b415170630 "2"^^ . . . _:b415170625 "2"^^ . _:b415170378 . _:b415170436 . _:b415170624 "2"^^ . _:b415170769 . _:b415170627 "2"^^ . . _:b415170626 "2"^^ . _:b415169856 . _:b415170353 . _:b415170637 "2"^^ . _:b415170636 "2"^^ . _:b415170826 . _:b415170120 . _:b415170639 "2"^^ . _:b415169964 . _:b415170638 "2"^^ . _:b415170895 . _:b415170633 "2"^^ . . _:b415170403 . _:b415170632 "2"^^ . _:b415170635 "2"^^ . . _:b415170634 "2"^^ . _:b415170645 "2"^^ . _:b415170644 "2"^^ . _:b415170647 "2"^^ . _:b415169688 . _:b415170395 . _:b415170646 "2"^^ . _:b415170641 "2"^^ . _:b415169918 . . _:b415170640 "2"^^ . . . _:b415170643 "2"^^ . _:b415170105 . _:b415170602 . _:b415170642 "2"^^ . _:b415170653 "2"^^ . _:b415170652 "2"^^ . _:b415170655 "2"^^ . _:b415169778 . _:b415169703 . _:b415170654 "2"^^ . _:b415170649 "2"^^ . _:b415170648 "2"^^ . _:b415170258 . _:b415169951 . _:b415170651 "2"^^ . . _:b415170650 "2"^^ . _:b415169896 . . _:b415170661 "2"^^ . _:b415170660 "2"^^ . _:b415170749 . _:b415169725 . _:b415170663 "2"^^ . _:b415170662 "2"^^ . _:b415170657 "2"^^ . _:b415170008 . _:b415170656 "2"^^ . . . _:b415170659 "2"^^ . . _:b415170351 . _:b415170658 "2"^^ . _:b415170669 "2"^^ . _:b415170662 . _:b415170706 . _:b415170668 "2"^^ . _:b415169904 . _:b415170671 "2"^^ . _:b415170550 . _:b415170670 "2"^^ . _:b415170665 "2"^^ . _:b415170664 "2"^^ . _:b415170517 . . _:b415170667 "2"^^ . _:b415170541 . _:b415169952 . _:b415170666 "2"^^ . . _:b415170371 . _:b415170677 "2"^^ . . _:b415170852 . _:b415170676 "2"^^ . . _:b415169793 . . . _:b415170679 "2"^^ . _:b415169849 . . _:b415170678 "2"^^ . _:b415170673 "2"^^ . _:b415170672 "2"^^ . _:b415170675 "2"^^ . . _:b415170674 "2"^^ . . _:b415170685 "2"^^ . . . . _:b415170684 "2"^^ . . _:b415170687 "2"^^ . _:b415169830 . _:b415170686 "2"^^ . _:b415170681 "2"^^ . . _:b415170544 . . _:b415170680 "2"^^ . . _:b415170683 "2"^^ . _:b415170682 "2"^^ . . _:b415170693 "2"^^ . _:b415170692 "2"^^ . _:b415170695 "2"^^ . _:b415170694 "2"^^ . _:b415170689 "2"^^ . . _:b415169998 . _:b415170688 "2"^^ . . _:b415170691 "2"^^ . . _:b415170690 "2"^^ . . _:b415170701 "2"^^ . . _:b415170700 "2"^^ . _:b6141887 . _:b415170652 . _:b415170505 . _:b415170703 "2"^^ . _:b415170702 "2"^^ . _:b415170697 "2"^^ . . _:b415170696 "2"^^ . . . _:b415170699 "2"^^ . _:b415170698 "2"^^ . _:b415170135 . _:b415170709 "2"^^ . _:b415170708 "2"^^ . _:b415169707 . . _:b415170711 "2"^^ . _:b415170736 . _:b415170710 "2"^^ . _:b415170705 "2"^^ . _:b415170704 "2"^^ . _:b415170707 "2"^^ . _:b415170392 . . _:b415170706 "2"^^ . _:b415170717 "2"^^ . _:b415170375 . _:b415169716 . _:b415170716 "2"^^ . _:b415169901 . . _:b415170367 . _:b415170719 "2"^^ . _:b415169909 . _:b415170718 "2"^^ . _:b415170643 . _:b415170713 "2"^^ . _:b415170712 "2"^^ . _:b415170715 "2"^^ . _:b415169753 . _:b415170714 "2"^^ . _:b415170287 . _:b415170725 "2"^^ . _:b415170724 "2"^^ . _:b415170528 . _:b415170727 "2"^^ . _:b415170408 . _:b415170726 "2"^^ . _:b415170721 "2"^^ . _:b415169740 . _:b415170720 "2"^^ . _:b415170083 . _:b415170723 "2"^^ . _:b415170277 . _:b415170722 "2"^^ . _:b415170733 "2"^^ . _:b415169717 . _:b415169879 . _:b415170732 "2"^^ . . . . _:b415170735 "2"^^ . _:b415170864 . _:b415170734 "2"^^ . _:b415170816 . _:b415170729 "2"^^ . _:b415169754 . _:b415170728 "2"^^ . _:b415170696 . _:b415170837 . _:b415170731 "2"^^ . _:b415170730 "2"^^ . _:b415169804 . _:b415170741 "2"^^ . _:b415170740 "2"^^ . . . _:b415170743 "2"^^ . . . _:b415170742 "2"^^ . _:b415170146 . _:b415170737 "2"^^ . . _:b415169877 . _:b415170332 . _:b415170736 "2"^^ . _:b415170739 "2"^^ . _:b415170738 "2"^^ . _:b415170101 . . _:b415170749 "2"^^ . _:b415170723 . . _:b415170748 "2"^^ . . _:b415170751 "2"^^ . _:b415170750 "2"^^ . . _:b415170745 "2"^^ . _:b415170744 "2"^^ . . _:b415170747 "2"^^ . . _:b415170746 "2"^^ . . _:b415170813 . _:b415170757 "2"^^ . . _:b415170309 . _:b415170756 "2"^^ . _:b415170308 . . _:b415170683 . _:b415170407 . _:b415170759 "2"^^ . _:b415170311 . _:b415170758 "2"^^ . _:b415170310 . . _:b415170753 "2"^^ . _:b415170307 . _:b415170305 . _:b415170901 . _:b415170752 "2"^^ . _:b415170304 . . . _:b415170755 "2"^^ . _:b415170307 . _:b415170754 "2"^^ . _:b415170306 . . _:b415170765 "2"^^ . _:b415170317 . . _:b415170764 "2"^^ . _:b415170316 . _:b415170620 . _:b415170767 "2"^^ . _:b415170319 . _:b415170766 "2"^^ . . _:b415170318 . . . _:b415170761 "2"^^ . _:b415170313 . _:b415170586 . _:b415170760 "2"^^ . _:b415170312 . _:b415170763 "2"^^ . _:b415170315 . _:b415170356 . . _:b415170762 "2"^^ . _:b415170314 . _:b415170328 . _:b415170773 "2"^^ . _:b415170325 . _:b415170768 . _:b415170772 "2"^^ . _:b415170324 . _:b415170775 "2"^^ . _:b415170327 . _:b415170774 "2"^^ . _:b415170326 . _:b415170769 "2"^^ . _:b415170321 . _:b415170768 "2"^^ . _:b415170320 . _:b415169741 . _:b415170771 "2"^^ . _:b415170323 . . _:b415170770 "2"^^ . _:b415170322 . _:b415170781 "2"^^ . _:b415170333 . . _:b415170780 "2"^^ . _:b415170332 . _:b415170783 "2"^^ . _:b415170335 . _:b415170782 "2"^^ . _:b415170334 . _:b415170777 "2"^^ . _:b415170329 . _:b415170776 "2"^^ . _:b415170328 . _:b415170366 . _:b415170779 "2"^^ . _:b415170331 . _:b415170778 "2"^^ . _:b415169715 . _:b415170330 . _:b415170789 "2"^^ . _:b415170459 . _:b415170341 . _:b415170192 . _:b415170788 "2"^^ . _:b415170340 . . _:b415170791 "2"^^ . . _:b415170031 . _:b415170343 . _:b415170790 "2"^^ . _:b415170342 . . . _:b415170785 "2"^^ . _:b415170337 . . _:b415170784 "2"^^ . . _:b415170336 . _:b415170787 "2"^^ . _:b415170339 . _:b415170786 "2"^^ . _:b415170338 . . _:b415170539 . _:b415170797 "2"^^ . _:b415170349 . _:b415170425 . _:b415170796 "2"^^ . _:b415170757 . _:b415170348 . _:b415169822 . _:b415170045 . _:b415170799 "2"^^ . _:b415170351 . _:b415170400 . _:b415170798 "2"^^ . _:b415170350 . _:b415170793 "2"^^ . _:b415170345 . _:b415170792 "2"^^ . _:b415170344 . . _:b415170795 "2"^^ . _:b415170347 . _:b415170794 "2"^^ . _:b415170346 . _:b415170805 "2"^^ . . _:b415170357 . _:b415170339 . _:b415170804 "2"^^ . _:b415170356 . . . _:b415170807 "2"^^ . . _:b415170359 . _:b415170806 "2"^^ . _:b415170358 . . . _:b415170801 "2"^^ . . _:b415170353 . _:b415170800 "2"^^ . _:b415170415 . _:b415170352 . _:b415170803 "2"^^ . _:b415170355 . _:b415170305 . _:b415170802 "2"^^ . _:b415170354 . _:b415170813 "2"^^ . _:b415170365 . _:b415169871 . _:b415170812 "2"^^ . . . _:b415170364 . _:b415170815 "2"^^ . _:b415170367 . _:b415170216 . _:b415170814 "2"^^ . _:b415170366 . . _:b415170809 "2"^^ . _:b415170361 . _:b415170702 . _:b415170808 "2"^^ . _:b415170360 . _:b415170811 "2"^^ . _:b415170363 . _:b415170810 "2"^^ . _:b415170362 . . _:b415170821 "2"^^ . _:b415170373 . _:b415170820 "2"^^ . _:b415170372 . . _:b415170823 "2"^^ . . _:b415170375 . _:b415170822 "2"^^ . _:b415170374 . . _:b415170817 "2"^^ . _:b415170369 . _:b415170816 "2"^^ . _:b415170368 . _:b415169826 . _:b415170819 "2"^^ . _:b415170371 . _:b415170818 "2"^^ . _:b415170370 . _:b415170829 "2"^^ . _:b415170381 . _:b415170828 "2"^^ . _:b415170380 . _:b415170831 "2"^^ . _:b415170405 . _:b415170383 . . _:b415170830 "2"^^ . _:b415170382 . . . _:b415170825 "2"^^ . _:b415170518 . _:b415170377 . _:b415170824 "2"^^ . _:b415170376 . _:b415170827 "2"^^ . _:b415170379 . _:b415170572 . _:b415170826 "2"^^ . _:b415170378 . _:b415170697 . _:b415169842 . . _:b415170837 "2"^^ . _:b415170389 . _:b415170836 "2"^^ . _:b415170388 . . _:b415170839 "2"^^ . _:b415170391 . _:b415170838 "2"^^ . _:b415170390 . . _:b415170833 "2"^^ . _:b415170385 . _:b415170832 "2"^^ . _:b415170384 . . . _:b415170835 "2"^^ . _:b415170387 . . _:b415170834 "2"^^ . _:b415170386 . . _:b415170845 "2"^^ . _:b415170845 . _:b415170397 . _:b415170462 . _:b415170844 "2"^^ . _:b415169709 . _:b415170396 . . . _:b415170847 "2"^^ . _:b415170399 . . _:b415170846 "2"^^ . _:b415170398 . . _:b415170841 "2"^^ . _:b415170393 . _:b415170840 "2"^^ . _:b415170392 . _:b415169692 . . _:b415170843 "2"^^ . _:b415170395 . . _:b415170842 "2"^^ . _:b415170394 . _:b415170009 . _:b415170853 "2"^^ . _:b415170405 . _:b415170316 . _:b415170852 "2"^^ . . _:b415170404 . _:b415170285 . _:b415170828 . _:b415170855 "2"^^ . _:b415170407 . _:b415170854 "2"^^ . _:b415170406 . . . _:b415170849 "2"^^ . _:b415170401 . . _:b415170535 . _:b415170848 "2"^^ . . _:b415170400 . . _:b415170851 "2"^^ . _:b415170403 . _:b415170876 . _:b415170850 "2"^^ . _:b415170402 . . _:b415170861 "2"^^ . _:b415170413 . . _:b415169959 . _:b415170860 "2"^^ . _:b415170412 . _:b415170357 . . _:b415170863 "2"^^ . _:b415170415 . _:b415170862 "2"^^ . _:b415170414 . _:b415170857 "2"^^ . _:b415170409 . _:b6141883 . _:b415170856 "2"^^ . _:b415170408 . _:b6141880 . _:b415170859 "2"^^ . _:b415170411 . _:b6141881 . _:b415170858 "2"^^ . _:b415170410 . _:b415170869 "2"^^ . _:b415170421 . _:b415170622 . _:b415170868 "2"^^ . _:b415170420 . _:b415170871 "2"^^ . _:b415170423 . _:b415170381 . _:b415170870 "2"^^ . _:b415169809 . _:b415170422 . _:b415170865 "2"^^ . _:b6141879 "methods" . _:b415170417 . _:b415169985 . _:b415170864 "2"^^ . _:b415170416 . _:b415169813 . . . . _:b415170867 "2"^^ . _:b415169972 . _:b415170419 . _:b415170866 "2"^^ . _:b415170418 . _:b415170704 . . _:b415170877 "2"^^ . _:b415170429 . _:b415170876 "2"^^ . _:b415170428 . _:b415170879 "2"^^ . _:b415170431 . _:b415170046 . _:b415169750 . . _:b415170878 "2"^^ . _:b415170430 . _:b415170873 "2"^^ . _:b415170425 . _:b415170872 "2"^^ . _:b415170424 . _:b415170691 . _:b415170875 "2"^^ . _:b415170427 . _:b415170874 "2"^^ . _:b415170426 . _:b415170885 "2"^^ . _:b415170693 . _:b415170437 . _:b415170884 "2"^^ . _:b415170436 . _:b415170887 "2"^^ . _:b415170439 . _:b415170886 "2"^^ . _:b415170438 . . _:b415170782 . _:b415170881 "2"^^ . _:b415170433 . _:b415170508 . _:b415169728 . . _:b415170880 "2"^^ . . _:b415170432 . . _:b415170883 "2"^^ . _:b415170435 . _:b415170882 "2"^^ . _:b415170434 . _:b415170893 "2"^^ . _:b415170445 . _:b415170892 "2"^^ . _:b415170444 . _:b415170895 "2"^^ . . _:b415170447 . _:b415170368 . _:b415170894 "2"^^ . _:b415170446 . _:b415170880 . _:b415170889 "2"^^ . _:b415170441 . . _:b415170888 "2"^^ . _:b415170440 . . _:b6141889 . . _:b415170891 "2"^^ . _:b415170443 . _:b415170890 "2"^^ . _:b415170442 . _:b415170901 "2"^^ . _:b415170453 . _:b415169888 . _:b415170900 "2"^^ . _:b415169883 . _:b415170452 . _:b415170903 "2"^^ . . _:b415170455 . _:b415170631 . _:b415170902 "2"^^ . _:b415170454 . _:b415170897 "2"^^ . _:b415170635 . _:b415170449 . _:b415170896 "2"^^ . _:b415170448 . . _:b415170899 "2"^^ . _:b415170451 . _:b415169994 . _:b415170898 "2"^^ . _:b415170450 . _:b415170909 "2"^^ . _:b415170461 . _:b415169993 . _:b415170908 "2"^^ . _:b415170460 . _:b415170463 . _:b415170910 "2"^^ . _:b415170462 . _:b415170905 "2"^^ . _:b415170457 . . _:b415170904 "2"^^ . . _:b415170456 . _:b415169748 . _:b415170309 . _:b415170907 "2"^^ . _:b415170459 . _:b415170380 . _:b415170906 "2"^^ . _:b415170458 . . . _:b415170469 . . _:b415170468 . . _:b415170471 . . _:b415170470 . _:b415170465 . _:b415169854 . _:b415170464 . _:b415170467 . _:b415170577 . _:b415170466 . _:b415170477 . _:b415170476 . _:b415170268 . _:b415170486 . _:b415170479 . _:b6141893 "The analysis utilized nine gene sets that were previously defined to be over-expressed in ES cells and performed as previously described.>>29<<" . _:b415170478 . _:b415170473 . . _:b415170472 . _:b415170194 . _:b415170475 . _:b415170474 . . . _:b415170485 . _:b415170811 . _:b415170484 . _:b415170487 . _:b415170486 . . . . . _:b415170481 . _:b415170480 . . _:b415170483 . _:b415170037 . _:b415170897 . _:b415170482 . _:b415170493 . . . _:b415170908 . _:b415170853 . _:b415170492 . . _:b415170495 . _:b415170494 . . . _:b415170489 . . _:b415170488 . . . "10.1038%2Fng.465" . _:b415170491 . _:b415170490 . _:b415170501 . . _:b415170500 . _:b415170503 . _:b415170889 . _:b415169772 . _:b415170502 . . . _:b415170497 . . _:b415170496 . . _:b415170499 . _:b415170655 . _:b415170498 . _:b415170204 . _:b415170441 . _:b415170509 . . _:b415170075 . _:b415170508 . _:b415170738 . _:b415170511 . _:b415170510 . _:b415170505 . . _:b415170504 . . _:b415170507 . . . _:b415170506 . _:b415169784 . _:b415170354 . _:b415170517 . . _:b415170516 . _:b415169807 . _:b415170519 . _:b415169876 . _:b415170518 . _:b415170513 . . _:b415170512 . . _:b415170515 . . _:b415170514 . _:b415170714 . . _:b415170525 . _:b415170524 . _:b415170527 . _:b415170526 . _:b415170206 . _:b415170521 . . _:b415170520 . _:b415170523 . _:b415170522 . _:b6141891 . _:b415170533 . _:b415170532 . _:b415170535 . _:b415170534 . _:b415170529 . _:b415170022 . _:b415170528 . _:b415170531 . _:b415170530 . . . _:b415170722 . . _:b415170541 . _:b415170112 . _:b415170540 . _:b415170543 . . . _:b415170542 . _:b415170537 . _:b415170291 . _:b415170536 . . _:b415170539 . _:b415170538 . . _:b415170549 . _:b415170548 . _:b415170551 . _:b415170550 . _:b415170545 . . _:b415170664 . _:b415170544 . _:b415170547 . . _:b415170088 . _:b415170546 . . _:b415170557 . . _:b415170556 . _:b415170687 . _:b415170559 . _:b415170600 . . _:b415170558 . . . _:b415170033 . _:b415170553 . _:b415170547 . _:b415170905 . _:b415170552 . _:b415170555 . _:b415170711 . _:b415170554 . _:b415170053 . _:b415170052 . . _:b415170055 . _:b415170054 . _:b415170256 . _:b415170772 . _:b415170049 . _:b415170103 . _:b415169962 . . _:b415170048 . . . _:b415170051 . _:b415170050 . . _:b415170061 . . _:b415170060 . _:b415170063 . . _:b415170062 . _:b415170195 . . _:b415170057 . _:b415170492 . _:b415170056 . _:b415169700 . _:b415170059 . _:b415170058 . _:b415170815 . _:b415170069 . _:b415170068 . . _:b415170262 . _:b415170071 . _:b415170298 . . _:b415170070 . . _:b415170065 . _:b415170064 . _:b415170067 . _:b415170066 . . _:b415170330 . . _:b415170077 . _:b415170076 . _:b415170079 . . _:b415170078 . _:b415170073 . _:b415170270 . _:b415170273 . _:b415170072 . _:b415170075 . . _:b415170074 . . _:b415170085 . . . _:b415170084 . _:b415170729 . _:b415170087 . _:b415170086 . . _:b415170081 . . _:b415170080 . . _:b415170083 . . . . _:b415170082 . _:b415170235 . . _:b415170093 . . _:b415170092 . _:b415170095 . . . _:b415170094 . _:b415170089 . _:b415170021 . . _:b415170088 . _:b415170241 . _:b415170091 . _:b415170090 . . _:b415169843 . _:b415170101 . _:b415170100 . . _:b415170103 . _:b415170207 . . _:b415170102 . _:b415170785 . _:b415170097 . _:b415170096 . _:b415170099 . _:b415170098 . _:b415170109 . _:b415169744 . _:b415170840 . _:b415170108 . . . _:b415170111 . . _:b415170110 . _:b415169860 . _:b415169942 . _:b415170105 . . _:b415170344 . . _:b415170104 . . _:b415170107 . . . _:b415170106 . _:b415170117 . _:b415170116 . _:b415169722 . _:b415170119 . _:b415170896 . . _:b415170118 . . _:b415170113 . _:b415170112 . _:b415170115 . _:b415170114 . . . _:b415170125 . . _:b415170124 . . _:b415170127 . _:b415170126 . _:b415170418 . _:b415170121 . _:b415170261 . _:b415170120 . _:b415170123 . _:b415170862 . _:b415170122 . _:b415170593 . _:b415170278 . _:b415170133 . _:b415169719 . _:b415169746 . _:b415170838 . _:b415170132 . _:b415170135 . _:b415170134 . . _:b415170129 . . _:b415170128 . _:b415170131 . _:b415170201 . _:b415170130 . _:b415170141 . _:b415169885 . . _:b415170140 . _:b415170703 . _:b415170143 . _:b415170610 . . _:b415170142 . _:b415170137 . _:b415169844 . _:b415170136 . _:b415170343 . _:b415170139 . . . _:b415170138 . _:b415170532 . _:b415170149 . . _:b415169679 . . _:b415170148 . . _:b415170151 . . . _:b415170150 . . . . _:b415170145 . _:b415170144 . . . _:b415169866 . _:b415170292 . _:b415170147 . . _:b415170146 . . . _:b415170157 . . . _:b415170156 . _:b415170159 . _:b415169853 . _:b415170158 . . _:b415170153 . . _:b415170152 . . . . _:b415170155 . _:b415169852 . _:b415170203 . _:b415170154 . _:b415170352 . _:b415170165 . . _:b415170164 . . _:b415170167 . _:b415170858 . _:b415170166 . _:b415170117 . _:b415170161 . _:b415170160 . . _:b415170163 . . . _:b415170162 . _:b415170745 . . . _:b415170173 . . _:b415170426 . _:b415170172 . _:b415169681 . _:b415170175 . _:b415170174 . . . _:b415170169 . _:b415170168 . _:b415170171 . _:b415170170 . . _:b415170625 . _:b415170181 . . _:b415170180 . _:b415169873 . _:b415170183 . _:b415170182 . _:b415170177 . _:b415170176 . . _:b415170796 . _:b415170179 . _:b415170860 . _:b415169917 . _:b415170178 . _:b415170189 . _:b415170623 . _:b415170188 . _:b415170681 . . _:b415170191 . _:b415170233 . _:b415170190 . _:b415170185 . _:b415170184 . _:b415170187 . _:b6141879 _:b6141880 . _:b415170186 . _:b6141879 _:b6141881 . _:b6141879 _:b6141882 . _:b6141879 _:b6141883 . _:b6141879 _:b6141884 . _:b415170197 . _:b415169891 . _:b6141879 _:b6141885 . _:b6141879 _:b6141886 . _:b6141879 _:b6141887 . _:b415170196 . _:b415170567 . _:b415170199 . . _:b415170198 . . _:b415170598 . _:b415170193 . _:b415169791 . . _:b415170192 . _:b415170195 . _:b415169939 . _:b415170194 . _:b415170205 . _:b415170204 . _:b415170207 . _:b415169792 . _:b415170206 . _:b415170201 . _:b415170422 . _:b415170200 . _:b415170203 . _:b415170202 . _:b415170213 . _:b415170212 . . _:b415170743 . _:b415170215 . _:b415170214 . . . _:b415170081 . _:b415170209 . _:b415170208 . . _:b415170211 . _:b415170210 . . _:b415170221 . _:b415170220 . _:b415170040 . _:b415170223 . _:b415170140 . _:b415170222 . _:b415170217 . _:b415169878 . _:b6141879 _:b6141888 . _:b415170216 . _:b6141879 _:b6141889 . _:b6141879 _:b6141890 . . _:b6141879 _:b6141891 . _:b6141879 _:b6141892 . _:b415170219 . _:b6141879 _:b6141893 . . _:b6141879 _:b6141894 . _:b415170218 . . . _:b415170229 . _:b415170607 . _:b415170228 . _:b415169997 . _:b415170231 . . _:b415170230 . _:b415170663 . . _:b415170225 . . _:b415170224 . _:b415170227 . _:b6141889 "33 We applied RMA and quantile normalization>>34<< and the matchprobes package in the Bioconductor framework35 to create one single data set." . _:b415170310 . _:b415170226 . _:b415169858 . _:b415170237 . . _:b415170236 . _:b415169958 . _:b415170239 . _:b415170238 . _:b415170678 . _:b415170233 . _:b415170232 . . _:b415170235 . . _:b415170234 . . _:b415170245 . _:b415170244 . . _:b415170247 . . _:b415170614 . _:b415170246 . _:b415170241 . _:b415170867 . . _:b415170240 . _:b415170243 . _:b415170242 . . _:b415170253 . . _:b415170252 . . _:b415170255 . . _:b415170254 . _:b415170249 . _:b415170248 . . _:b415170842 . _:b415170251 . _:b415170707 . _:b415170250 . _:b415170487 . _:b415170261 . . _:b415170260 . _:b415170263 . _:b415170262 . . _:b415170257 . _:b415170256 . _:b415170259 . . _:b415170086 . _:b415170258 . _:b415170269 . _:b415170129 . _:b415170471 . . . _:b415170268 . . . _:b415170271 . _:b415170270 . _:b415170265 . _:b415170264 . _:b415170804 . _:b415170267 . _:b415170266 . _:b415170386 . _:b415170616 . _:b415170229 . _:b415170277 . _:b415169777 . _:b415169698 . _:b415169697 . _:b415170276 . . _:b415170279 . _:b415170278 . _:b6141885 . . _:b415170273 . _:b415170272 . _:b415170275 . . _:b415170481 . _:b415170274 . _:b415170285 . . . _:b415170284 . _:b415170806 . _:b415169960 . _:b415170287 . . _:b415170286 . _:b415170281 . . _:b415170326 . _:b415170280 . . _:b415170283 . _:b415170325 . _:b415170282 . _:b415169765 . _:b415170063 . _:b415170293 . . . _:b415170292 . . _:b415170295 . _:b415170294 . . _:b415170289 . . _:b415170288 . _:b415170694 . . _:b415170291 . . _:b415170290 . . _:b415170301 . . _:b415170300 . _:b415169963 . _:b415170303 . . _:b415170302 . _:b415170297 . _:b415170296 . _:b415170851 . _:b415170427 . _:b415170299 . . _:b415170298 . _:b415169797 . _:b415170208 . _:b415169796 . _:b415169799 . _:b415170067 . _:b415169798 . _:b415170827 . _:b415169793 . . _:b415169792 . _:b415169795 . _:b415169794 . _:b415169805 . . _:b415169804 . _:b415169807 . _:b415169806 . _:b415169686 . _:b415169801 . _:b415169800 . _:b415169819 . _:b415169803 . _:b415169802 . _:b415170453 . . _:b415169813 . _:b415169812 . _:b415169815 . . . _:b415169814 . _:b415170843 . _:b415169809 . _:b415169808 . _:b415169811 . _:b415169810 . _:b415170457 . _:b415169821 . _:b415169847 . _:b415169820 . . _:b415169783 . _:b415169823 . _:b415170087 . . _:b415169822 . . _:b415169817 . _:b415169816 . _:b415169819 . _:b415170159 . _:b415170004 . _:b415169818 . _:b415169829 . _:b415170401 . _:b415169828 . _:b415169982 . _:b415169831 . . _:b415169830 . _:b415170234 . _:b415169825 . _:b415170746 . _:b415169824 . _:b415169868 . _:b415170315 . . _:b415169827 . _:b415170133 . _:b415170721 . . _:b415169826 . _:b415169923 . . _:b415169837 . _:b415169836 . . . _:b415169785 . _:b415169839 . . . _:b415169838 . . _:b415169897 . _:b415169820 . _:b415170830 . _:b415169833 . _:b415169832 . _:b415170106 . _:b415169817 . _:b415169835 . _:b415169834 . _:b6141894 . _:b415170491 . _:b415170480 . _:b415169845 . . _:b415169844 . . _:b415169847 . _:b415169846 . _:b415169841 . _:b415169840 . _:b415170222 . _:b415169843 . . _:b415169823 . _:b415169842 . . _:b415169853 . _:b415169852 . _:b415170632 . _:b415169855 . _:b415169854 . _:b415169931 . _:b415169849 . _:b415169848 . _:b6141884 . _:b415169851 . _:b415169806 . . _:b415169850 . _:b415170003 . _:b415169861 . _:b415169860 . _:b415169863 . _:b415169862 . . _:b415169857 . _:b415169856 . _:b415169859 . . _:b415169858 . _:b415170552 . _:b415169805 . _:b415170562 . _:b415169869 . _:b415169868 . _:b415169945 . _:b415169871 . _:b415169870 . _:b415170012 . _:b415169865 . _:b415170360 . _:b415170617 . _:b415169864 . _:b415170884 . _:b415169867 . _:b415169866 . _:b415169877 . _:b415169876 . . _:b415169879 . _:b415169878 . _:b415170881 . _:b415169873 . _:b415170761 . _:b415169872 . _:b415170036 . _:b415170293 . _:b415169875 . _:b415170900 . _:b415169874 . _:b415169885 . _:b415169884 . _:b415169887 . _:b415169886 . . . _:b415170096 . _:b415169881 . _:b415170153 . _:b415169880 . _:b415170340 . _:b415169883 . _:b415169882 . _:b415169941 . _:b415169928 . _:b415169893 . _:b415169925 . _:b415169892 . . _:b415169895 . . _:b415169930 . _:b415169894 . _:b415169889 . . . _:b415170038 . _:b415169888 . _:b415170686 . _:b415170740 . _:b415169891 . . _:b415169890 . _:b415169901 . . . . _:b415169800 . _:b415169900 . . . . _:b415169903 . _:b415169902 . _:b415169897 . _:b415169896 . _:b415170555 . _:b415169899 . . _:b415170584 . . _:b415169898 . _:b415170438 . _:b415170594 . _:b415169909 . _:b415170413 . . _:b415170282 . . . _:b415169908 . _:b415169911 . _:b415169910 . . _:b415169905 . _:b415170242 . _:b415169904 . . _:b415169907 . _:b415169710 . . _:b415169906 . _:b415170787 . _:b415170464 . . _:b415169917 . _:b6141887 "Analysis was performed with RIGER (RNAi Gene Enrichment Ranking)16,>>17<< to compare the effects of each construct on the four 3q26.33-amplified lines to the construct\u2019s effects in control cell lines to determine an enrichment score for each construct." . _:b415169916 . . _:b415169919 . _:b415170514 . _:b415169918 . . _:b415169913 . _:b415169912 . _:b415170151 . _:b415169922 . _:b415169915 . _:b415169914 . _:b415170113 . _:b415169834 . _:b415169831 . _:b415169925 . _:b415169887 . _:b415170176 . . _:b415169927 . _:b415169924 . _:b415169927 . _:b415170303 . . _:b415169926 . _:b415169921 . _:b415170502 . _:b415169920 . _:b415169923 . . _:b415169922 . . _:b415170389 . _:b415169933 . _:b415169932 . . _:b415169935 . . _:b415169934 . _:b415169682 . . . _:b415169929 . . . _:b415169928 . _:b415169931 . _:b415169930 . . _:b415170882 . _:b415169941 . _:b415169940 . _:b415170802 . _:b415169943 . . _:b415169942 . . _:b415169937 . . _:b415170647 . . _:b415169936 . . _:b415169939 . . . _:b415169794 . . _:b415169938 . _:b415169733 . _:b415169949 . _:b415169948 . _:b415169951 . _:b415169678 . _:b415169950 . . _:b415169945 . _:b415170904 . . _:b415169944 . _:b415169947 . . . _:b415169946 . . _:b415169957 . _:b415170178 . _:b415169956 . . _:b415170873 . . _:b415170072 . _:b415169959 . . . _:b415169958 . _:b415170187 . _:b415169953 . _:b415169952 . _:b415169955 . _:b415169810 . _:b415169954 . . . _:b415169965 . . _:b415170670 . _:b415169964 . _:b415170618 . _:b415169967 . _:b415170124 . _:b415170666 . _:b415169966 . _:b415169961 . _:b415169960 . . . _:b415169963 . _:b415169962 . _:b415169881 . _:b415170859 . _:b415169973 . _:b415169999 . _:b415169972 . _:b415169975 . _:b415169974 . . _:b415169969 . _:b6141884 "CTD-2348H10) and reference (clone RP11-286G5) were obtained from the BACPAC Resource Center (Oakland, CA) and also from Invitrogen (Carlsbad, CA). Tissue hybridization, washing, and color detection were performed as described previously.>>32<< The samples were analyzed under a 60x oil immersion objective using an Olympus BX-51 fluorescence microscope, and the CytoVision FISH imaging and capturing software (Applied Imaging, San Jose, CA)." . _:b415169968 . _:b415169971 . . _:b415170302 . _:b6141879 . _:b415169970 . _:b415169981 . _:b415170148 . . _:b415169980 . _:b415169983 . . _:b415169982 . . _:b6141884 . _:b415169977 . . . . _:b415170416 . _:b6141885 . _:b415169976 . _:b415170870 . _:b6141886 . . _:b415169979 . . _:b6141887 . _:b415170095 . _:b415169978 . _:b6141880 . _:b415169989 . . _:b6141881 . _:b415169988 . . _:b6141882 . _:b415169991 . _:b415170099 . _:b415169981 . _:b6141883 . . _:b415169990 . _:b6141892 . _:b415169985 . _:b6141893 . _:b415169984 . _:b6141894 . _:b415169987 . _:b415170266 . _:b415169986 . . . _:b6141888 . _:b415169997 . _:b6141889 . _:b415169996 . _:b6141890 . _:b415170435 . _:b415169999 . _:b6141891 . _:b415169998 . . _:b415169993 . _:b415170671 . . _:b415169992 . _:b415169995 . . _:b415169994 . _:b415170538 . . _:b415170005 . _:b415170004 . _:b415170458 . _:b415170007 . . _:b415170006 . . _:b415170066 . _:b415170001 . . _:b415170184 . _:b415170000 . _:b415170673 . _:b415170003 . . . _:b415170002 . . . . _:b415170013 . _:b415169687 . _:b415170362 . _:b415170012 . _:b415170015 . _:b415170014 . _:b415170128 . _:b415170009 . _:b415170495 . _:b415170627 . _:b415170008 . _:b415170011 . _:b415170299 . _:b415170010 . _:b415170725 . _:b415170021 . _:b415170668 . _:b415170020 . _:b415170023 . _:b415169742 . . _:b415169711 . _:b415170022 . _:b415170821 . . _:b415170335 . . _:b415170017 . _:b415170016 . _:b415170019 . . . _:b415170018 . _:b415170442 . _:b415170029 . _:b415170111 . _:b415170028 . . _:b415170031 . . . _:b415170061 . _:b415170030 . _:b415170025 . . _:b415170024 .