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n6:19918372 n7:0 n9:10.1155%2F2009%2F595126 n10:0
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introduction
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namely, inflammation leading to haemostasis and clot formation, fibroplasia and neovascularization, formation of granulation tissue, reepithelialization, and finally the formation of new extracellular matrix and tissue remodeling [>>2<<]. Inflammation is closely associated with the release of inflammatory mediators including Reactive Oxygen Species (ROS), Reactive Nitrogen Species (RNS), along with their derivatives.
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Chitosan and alginate are well known for accelerating the healing of wounds in humans [>>3<<, 4]. Chitosan (CS), a natural cationic polymer, is biologically renewable, biodegradable, biocompatible, nonantigenic, nontoxic, and biofunctional, and it can accelerate the wound healing process enhancing the functions of inflammatory
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polymer, is biologically renewable, biodegradable, biocompatible, nonantigenic, nontoxic, and biofunctional, and it can accelerate the wound healing process enhancing the functions of inflammatory cells, macrophages, and fibroblasts [>>3<<, 5, 6]. Alginate, an anionic polymer, also is biocompatible, hydrophilic, and biodegradable under normal physiological conditions.
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polymer, is biologically renewable, biodegradable, biocompatible, nonantigenic, nontoxic, and biofunctional, and it can accelerate the wound healing process enhancing the functions of inflammatory cells, macrophages, and fibroblasts [3, >>5<<, 6]. Alginate, an anionic polymer, also is biocompatible, hydrophilic, and biodegradable under normal physiological conditions.
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is biologically renewable, biodegradable, biocompatible, nonantigenic, nontoxic, and biofunctional, and it can accelerate the wound healing process enhancing the functions of inflammatory cells, macrophages, and fibroblasts [3, 5, >>6<<]. Alginate, an anionic polymer, also is biocompatible, hydrophilic, and biodegradable under normal physiological conditions.
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Curcumin (diferuloylmethane) is an orange-yellow component of turmeric (Curcuma longa), a spice often found in curry powder [>>8<<]. It has been shown to exhibit numerous activities. Various preclinical cell culture and animal studies suggest that curcumin has potential because of its pharmacological properties including anti-inflammatory [9, 10], antimicrobial [11],
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Various preclinical cell culture and animal studies suggest that curcumin has potential because of its pharmacological properties including anti-inflammatory [>>9<<, 10], antimicrobial [11], antiviral [12, 13], anticancer [14], antioxidant [15–17], chemosensitizer [18, 19], radiosensitizer [20, 21], and wound healing activities [22–24].
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Various preclinical cell culture and animal studies suggest that curcumin has potential because of its pharmacological properties including anti-inflammatory [9, >>10<<], antimicrobial [11], antiviral [12, 13], anticancer [14], antioxidant [15–17], chemosensitizer [18, 19], radiosensitizer [20, 21], and wound healing activities [22–24].
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Various preclinical cell culture and animal studies suggest that curcumin has potential because of its pharmacological properties including anti-inflammatory [9, 10], antimicrobial [11], antiviral [>>12<<, 13], anticancer [14], antioxidant [15–17], chemosensitizer [18, 19], radiosensitizer [20, 21], and wound healing activities [22–24].
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Various preclinical cell culture and animal studies suggest that curcumin has potential because of its pharmacological properties including anti-inflammatory [9, 10], antimicrobial [11], antiviral [12, >>13<<], anticancer [14], antioxidant [15–17], chemosensitizer [18, 19], radiosensitizer [20, 21], and wound healing activities [22–24].
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Various preclinical cell culture and animal studies suggest that curcumin has potential because of its pharmacological properties including anti-inflammatory [9, 10], antimicrobial [11], antiviral [12, 13], anticancer [>>14<<], antioxidant [15–17], chemosensitizer [18, 19], radiosensitizer [20, 21], and wound healing activities [22–24].
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Various preclinical cell culture and animal studies suggest that curcumin has potential because of its pharmacological properties including anti-inflammatory [9, 10], antimicrobial [11], antiviral [12, 13], anticancer [14], antioxidant [>>15<<–17], chemosensitizer [18, 19], radiosensitizer [20, 21], and wound healing activities [22–24].
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culture and animal studies suggest that curcumin has potential because of its pharmacological properties including anti-inflammatory [9, 10], antimicrobial [11], antiviral [12, 13], anticancer [14], antioxidant [15–17], chemosensitizer [>>18<<, 19], radiosensitizer [20, 21], and wound healing activities [22–24].
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and animal studies suggest that curcumin has potential because of its pharmacological properties including anti-inflammatory [9, 10], antimicrobial [11], antiviral [12, 13], anticancer [14], antioxidant [15–17], chemosensitizer [18, >>19<<], radiosensitizer [20, 21], and wound healing activities [22–24].
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suggest that curcumin has potential because of its pharmacological properties including anti-inflammatory [9, 10], antimicrobial [11], antiviral [12, 13], anticancer [14], antioxidant [15–17], chemosensitizer [18, 19], radiosensitizer [>>20<<, 21], and wound healing activities [22–24].
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that curcumin has potential because of its pharmacological properties including anti-inflammatory [9, 10], antimicrobial [11], antiviral [12, 13], anticancer [14], antioxidant [15–17], chemosensitizer [18, 19], radiosensitizer [20, >>21<<], and wound healing activities [22–24].
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of its pharmacological properties including anti-inflammatory [9, 10], antimicrobial [11], antiviral [12, 13], anticancer [14], antioxidant [15–17], chemosensitizer [18, 19], radiosensitizer [20, 21], and wound healing activities [>>22<<–24]. Topical applications of curcumin with its properties of anti-inflammatory antioxidant (free radical scavenging activity), induction of detoxification enzymes, and providing protection against degenerative disease in patients have
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(free radical scavenging activity), induction of detoxification enzymes, and providing protection against degenerative disease in patients have shown to improve significantly wound healing and protect tissues from oxidative damage [>>24<<].
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results and discussion
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This may be reasonably expected to be homogeneous throughout the sample, leading to a more regular pore size and fibrillar structure [>>6<<].
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